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Results: 1-25 | 26-48 |
Results: 26-48/48
CATALYTIC ROLE OF CYTOCHROME P4503A4 IN MULTIPLE PATHWAYS OF ALFENTANIL METABOLISM
Authors: LABROO RB THUMMEL KE KUNZE KL PODOLL T TRAGER WF KHARASCH ED
Citation: Rb. Labroo et al., CATALYTIC ROLE OF CYTOCHROME P4503A4 IN MULTIPLE PATHWAYS OF ALFENTANIL METABOLISM, Drug metabolism and disposition, 23(4), 1995, pp. 490-496
INTERPATIENT HETEROGENEITY IN EXPRESSION OF CYP3A4 AND CYP3A5 IN SMALL-BOWEL - LACK OF PREDICTION BY THE ERYTHROMYCIN BREATH TEST (VOL 22, PG 947, 1994)
Authors: LOWN KS KOLARS JC THUMMEL KE BARNETT JL KUNZE KL WRIGHTON SA WATKINS PB
Citation: Ks. Lown et al., INTERPATIENT HETEROGENEITY IN EXPRESSION OF CYP3A4 AND CYP3A5 IN SMALL-BOWEL - LACK OF PREDICTION BY THE ERYTHROMYCIN BREATH TEST (VOL 22, PG 947, 1994), Drug metabolism and disposition, 23(3), 1995, pp. 294-294
STEREOSELECTIVE METABOLISM OF ENFLURANE BY HUMAN LIVER CYTOCHROME-P450 2E1
Authors: GARTON KJ YUEN P MEINWALD J THUMMEL KE KHARASCH ED
Citation: Kj. Garton et al., STEREOSELECTIVE METABOLISM OF ENFLURANE BY HUMAN LIVER CYTOCHROME-P450 2E1, Drug metabolism and disposition, 23(12), 1995, pp. 1426-1430
DESIGNING SAFER CHEMICALS - PREDICTING THE RATES OF METABOLISM OF HALOGENATED ALKANES
Authors: YIN HQ ANDERS MW KORZEKWA KR HIGGINS L THUMMEL KE KHARASCH ED JONES JP
Citation: Hq. Yin et al., DESIGNING SAFER CHEMICALS - PREDICTING THE RATES OF METABOLISM OF HALOGENATED ALKANES, Proceedings of the National Academy of Sciences of the United Statesof America, 92(24), 1995, pp. 11076-11080
MECHANISMS OF STIRIPENTOL INTERACTIONS WITH CARBAMAZEPINE AND PHENYTOIN
Authors: MATHER GG BISHOP FE TRAGER WF KUNZE KK THUMMEL KE SHEN DD ROSKOS LK LEPAGE F GILLARDIN JM LEVY RH
Citation: Gg. Mather et al., MECHANISMS OF STIRIPENTOL INTERACTIONS WITH CARBAMAZEPINE AND PHENYTOIN, Epilepsia, 36, 1995, pp. 162-163
METABOLISM OF DAPSONE TO ITS HYDROXYLAMINE BY CYP2E1 IN-VITRO AND IN-VIVO
Authors: MITRA AK THUMMEL KE KALHORN TF KHARASCH ED UNADKAT JD SLATTERY JT
Citation: Ak. Mitra et al., METABOLISM OF DAPSONE TO ITS HYDROXYLAMINE BY CYP2E1 IN-VITRO AND IN-VIVO, Clinical pharmacology and therapeutics, 58(5), 1995, pp. 556-566
THE ERYTHROMYCIN BREATH TEST PREDICTS THE CLEARANCE OF MIDAZOLAM
Authors: LOWN KS THUMMEL KE BENEDICT PE SHEN DD TURGEON DK BERENT S WATKINS PB
Citation: Ks. Lown et al., THE ERYTHROMYCIN BREATH TEST PREDICTS THE CLEARANCE OF MIDAZOLAM, Clinical pharmacology and therapeutics, 57(1), 1995, pp. 16-24
STEREOSELECTIVE ENFLURANE BY HUMAN LIVER CYTOCHROME-P450 2E1
Authors: KHARASCH ED GARTON K MEINWALD J THUMMEL KE
Citation: Ed. Kharasch et al., STEREOSELECTIVE ENFLURANE BY HUMAN LIVER CYTOCHROME-P450 2E1, Anesthesiology, 83(3A), 1995, pp. 335-335
IDENTIFICATION OF THE HUMAN ENZYME RESPONSIBLE FOR HALOTHANE METABOLISM - A POSSIBLE STRATEGY TO PREVENT HALOTHANE HEPATITIS
Authors: KHARASCH ED THUMMEL KE HANKINS D MAUTZ D COX K
Citation: Ed. Kharasch et al., IDENTIFICATION OF THE HUMAN ENZYME RESPONSIBLE FOR HALOTHANE METABOLISM - A POSSIBLE STRATEGY TO PREVENT HALOTHANE HEPATITIS, Anesthesiology, 83(3A), 1995, pp. 344-344
HUMAN KIDNEY METHOXYFLURANE AND SEVOFLURANE METABOLISM - INTRARENAL FLUORIDE PRODUCTION AS A POSSIBLE MECHANISM OF METHOXYFLURANE NEPHROTOXICITY
Authors: KHARASCH ED HANKINS DC THUMMEL KE
Citation: Ed. Kharasch et al., HUMAN KIDNEY METHOXYFLURANE AND SEVOFLURANE METABOLISM - INTRARENAL FLUORIDE PRODUCTION AS A POSSIBLE MECHANISM OF METHOXYFLURANE NEPHROTOXICITY, Anesthesiology, 82(3), 1995, pp. 689-699
PH-DEPENDENT ONE-ELECTRON AND 2-ELECTRON OXIDATION OF ARBETHOXY-2,6-DIMETHYL-4-ETHYL-1,4-DIHYDROPYRIDINE CATALYZED BY HORSERADISH-PEROXIDASE
Authors: SUGIYAMA K CORREIA MA THUMMEL KE NAGATA K DARBYSHIRE JF OSAWA Y GILLETTE JR
Citation: K. Sugiyama et al., PH-DEPENDENT ONE-ELECTRON AND 2-ELECTRON OXIDATION OF ARBETHOXY-2,6-DIMETHYL-4-ETHYL-1,4-DIHYDROPYRIDINE CATALYZED BY HORSERADISH-PEROXIDASE, Chemical research in toxicology, 7(5), 1994, pp. 633-642
INTERPATIENT HETEROGENEITY IN EXPRESSION OF CYP3A4 AND CYP3A5 IN SMALL-BOWEL - LACK OF PREDICTION BY THE ERYTHROMYCIN BREATH TEST
Authors: LOWN KS KOLARS JC THUMMEL KE BARNETT JL KUNZE KL WRIGHTON SA WATKINS PB
Citation: Ks. Lown et al., INTERPATIENT HETEROGENEITY IN EXPRESSION OF CYP3A4 AND CYP3A5 IN SMALL-BOWEL - LACK OF PREDICTION BY THE ERYTHROMYCIN BREATH TEST, Drug metabolism and disposition, 22(6), 1994, pp. 947-955
USE OF MIDAZOLAM AS A HUMAN CYTOCHROME-P450 3A PROBE .1. IN-VITRO IN-VIVO CORRELATION IN LIVER-TRANSPLANT PATIENTS
Authors: THUMMEL KE SHEN DD PODOLL TD KUNZE KL TRAGER WF HARTWELL PS RAISYS VA MARSH CL MCVICAR JP BARR DM PERKINS JD CARITHERS RL
Citation: Ke. Thummel et al., USE OF MIDAZOLAM AS A HUMAN CYTOCHROME-P450 3A PROBE .1. IN-VITRO IN-VIVO CORRELATION IN LIVER-TRANSPLANT PATIENTS, The Journal of pharmacology and experimental therapeutics, 271(1), 1994, pp. 549-556
USE OF MIDAZOLAM AS A HUMAN CYTOCHROME-P450-3A PROBE .2. CHARACTERIZATION OF INTERINDIVIDUAL AND INTRAINDIVIDUAL HEPATIC CYP3A VARIABILITY AFTER LIVER-TRANSPLANTATION
Authors: THUMMEL KE SHEN DD PODOLL TD KUNZE KL TRAGER WF BACCHI CE MARSH CL MCVICAR JP BARR DM PERKINS JD CARITHERS RL
Citation: Ke. Thummel et al., USE OF MIDAZOLAM AS A HUMAN CYTOCHROME-P450-3A PROBE .2. CHARACTERIZATION OF INTERINDIVIDUAL AND INTRAINDIVIDUAL HEPATIC CYP3A VARIABILITY AFTER LIVER-TRANSPLANTATION, The Journal of pharmacology and experimental therapeutics, 271(1), 1994, pp. 557-566
PREFERRED ORIENTATIONS IN THE BINDING OF 4'-HYDROXYACETANILIDE (ACETAMINOPHEN) TO CYTOCHROME-P450 1A1 AND 2B1 ISOFORMS AS DETERMINED BY C-13-NMR AND N-15-NMR RELAXATION STUDIES
Authors: MYERS TG THUMMEL KE KALHORN TF NELSON SD
Citation: Tg. Myers et al., PREFERRED ORIENTATIONS IN THE BINDING OF 4'-HYDROXYACETANILIDE (ACETAMINOPHEN) TO CYTOCHROME-P450 1A1 AND 2B1 ISOFORMS AS DETERMINED BY C-13-NMR AND N-15-NMR RELAXATION STUDIES, Journal of medicinal chemistry, 37(6), 1994, pp. 860-867
HEPATOTOXICITY ASSOCIATED WITH ACETAMINOPHEN USAGE IN PATIENTS RECEIVING MULTIPLE-DRUG THERAPY FOR TUBERCULOSIS
Authors: NOLAN CM SANDBLOM RE THUMMEL KE SLATTERY JT NELSON SD
Citation: Cm. Nolan et al., HEPATOTOXICITY ASSOCIATED WITH ACETAMINOPHEN USAGE IN PATIENTS RECEIVING MULTIPLE-DRUG THERAPY FOR TUBERCULOSIS, Chest, 105(2), 1994, pp. 408-411
CLINICAL ENFLURANE METABOLISM BY CYTOCHROME-P450 2E1
Authors: KHARASCH ED THUMMEL KE MAUTZ D BOSSE S
Citation: Ed. Kharasch et al., CLINICAL ENFLURANE METABOLISM BY CYTOCHROME-P450 2E1, Clinical pharmacology and therapeutics, 55(4), 1994, pp. 434-440
HUMAN LIVER CARBAMAZEPINE METABOLISM - ROLE OF CYP3A4 AND CYP2C8 IN 10,11-EPOXIDE FORMATION
Authors: KERR BM THUMMEL KE WURDEN CJ KLEIN SM KROETZ DL GONZALEZ FJ LEVY RH
Citation: Bm. Kerr et al., HUMAN LIVER CARBAMAZEPINE METABOLISM - ROLE OF CYP3A4 AND CYP2C8 IN 10,11-EPOXIDE FORMATION, Biochemical pharmacology, 47(11), 1994, pp. 1969-1979
INHIBITION AND INDUCTION OF CYTOCHROME P4502E1-CATALYZED OXIDATION BYISONIAZID IN HUMANS
Authors: ZAND R NELSON SD SLATTERY JT THUMMEL KE KALHORN TF ADAMS SP WRIGHT JM
Citation: R. Zand et al., INHIBITION AND INDUCTION OF CYTOCHROME P4502E1-CATALYZED OXIDATION BYISONIAZID IN HUMANS, Clinical pharmacology and therapeutics, 54(2), 1993, pp. 142-149
SINGLE-DOSE DISULFIRAM INHIBITION OF CHLORZOXAZONE METABOLISM - A CLINICAL PROBE FOR P450-2E1
Authors: KHARASCH ED THUMMEL KE MHYRE J LILLIBRIDGE JH
Citation: Ed. Kharasch et al., SINGLE-DOSE DISULFIRAM INHIBITION OF CHLORZOXAZONE METABOLISM - A CLINICAL PROBE FOR P450-2E1, Clinical pharmacology and therapeutics, 53(6), 1993, pp. 643-650
OXIDATION OF ACETAMINOPHEN TO N-ACETYL-P-AMINOBENZOQUINONE IMINE BY HUMAN CYP3A4
Authors: THUMMEL KE LEE CA KUNZE KL NELSON SD SLATTERY JT
Citation: Ke. Thummel et al., OXIDATION OF ACETAMINOPHEN TO N-ACETYL-P-AMINOBENZOQUINONE IMINE BY HUMAN CYP3A4, Biochemical pharmacology, 45(8), 1993, pp. 1563-1569
IDENTIFICATION OF CYTOCHROME-P450 2E1 AS THE PREDOMINANT ENZYME CATALYZING HUMAN LIVER MICROSOMAL DEFLUORINATION OF SEVOFLURANE, ISOFLURANE, AND METHOXYFLURANE
Authors: KHARASCH ED THUMMEL KE
Citation: Ed. Kharasch et Ke. Thummel, IDENTIFICATION OF CYTOCHROME-P450 2E1 AS THE PREDOMINANT ENZYME CATALYZING HUMAN LIVER MICROSOMAL DEFLUORINATION OF SEVOFLURANE, ISOFLURANE, AND METHOXYFLURANE, Anesthesiology, 79(4), 1993, pp. 795-807
HUMAN ALFENTANIL METABOLISM BY CYTOCHROME-P450-3A3 4 - AN EXPLANATIONFOR THE INTERINDIVIDUAL VARIABILITY IN ALFENTANIL CLEARANCE/
Authors: KHARASCH ED THUMMEL KE
Citation: Ed. Kharasch et Ke. Thummel, HUMAN ALFENTANIL METABOLISM BY CYTOCHROME-P450-3A3 4 - AN EXPLANATIONFOR THE INTERINDIVIDUAL VARIABILITY IN ALFENTANIL CLEARANCE/, Anesthesia and analgesia, 76(5), 1993, pp. 1033-1039
Risultati: 1-25 | 26-48 |