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Results: 1-16 |
Results: 16
O-18 KINETIC ISOTOPE EFFECT STUDIES OF THE TYROSINE-HYDROXYLASE REACTION - EVIDENCE OF RATE-LIMITING OXYGEN ACTIVATION
Authors: FRANCISCO WA TIAN GC FITZPATRICK PF KLINMAN JP
Citation: Wa. Francisco et al., O-18 KINETIC ISOTOPE EFFECT STUDIES OF THE TYROSINE-HYDROXYLASE REACTION - EVIDENCE OF RATE-LIMITING OXYGEN ACTIVATION, Journal of the American Chemical Society, 120(17), 1998, pp. 4057-4062
DUAL INHIBITION OF HUMAN TYPE-4 PHOSPHODIESTERASE ISOSTATES BY (R-ASTERISK,R-ASTERISK)-(+ -)-METHYL -METHOXYPHENYL]-3-METHYL-1-PYRROLIDINECARBOXYLATE/
Authors: TIAN GC ROCQUE WJ WISEMAN JS THOMPSON IZ HOLMES WD DOMANICO PL STAFFORD JA FELDMAN PL LUTHER MA
Citation: Gc. Tian et al., DUAL INHIBITION OF HUMAN TYPE-4 PHOSPHODIESTERASE ISOSTATES BY (R-ASTERISK,R-ASTERISK)-(+ -)-METHYL -METHOXYPHENYL]-3-METHYL-1-PYRROLIDINECARBOXYLATE/, Biochemistry, 37(19), 1998, pp. 6894-6904
HUMAN RECOMBINANT PHOSPHODIESTERASE 4B2B BINDS (R)-ROLIPRAM AT A SINGLE-SITE WITH 2 AFFINITIES
Authors: ROCQUE WJ TIAN GC WISEMAN JS HOLMES WD ZAJACTHOMPSON I WILLARD DH PATEL IR WISELY GB CLAY WC KADWELL SH HOFFMAN CR LUTHER MA
Citation: Wj. Rocque et al., HUMAN RECOMBINANT PHOSPHODIESTERASE 4B2B BINDS (R)-ROLIPRAM AT A SINGLE-SITE WITH 2 AFFINITIES, Biochemistry, 36(46), 1997, pp. 14250-14261
IN-VIVO TIME-DEPENDENT INHIBITION OF HUMAN STEROID 5-ALPHA-REDUCTASE BY FINASTERIDE
Authors: TIAN GC
Citation: Gc. Tian, IN-VIVO TIME-DEPENDENT INHIBITION OF HUMAN STEROID 5-ALPHA-REDUCTASE BY FINASTERIDE, Journal of pharmaceutical sciences, 85(1), 1996, pp. 106-111
INHIBITION OF HUMAN STEROID 5-ALPHA REDUCTASES TYPE-I AND TYPE-II BY 6-AZA-STEROIDS - STRUCTURAL DETERMINANTS OF ONE-STEP VS 2-STEP MECHANISM
Authors: MOSS ML KUZMIC P STUART JD TIAN GC PERANTEAU AG FRYE SV KADWELL SH KOST TA OVERTON LK PATEL IR
Citation: Ml. Moss et al., INHIBITION OF HUMAN STEROID 5-ALPHA REDUCTASES TYPE-I AND TYPE-II BY 6-AZA-STEROIDS - STRUCTURAL DETERMINANTS OF ONE-STEP VS 2-STEP MECHANISM, Biochemistry, 35(11), 1996, pp. 3457-3464
AN OXYGEN-ISOTOPE EFFECT ON ACTIVATED BLEOMYCIN
Authors: TIAN GC BURGER RM DRLICA K
Citation: Gc. Tian et al., AN OXYGEN-ISOTOPE EFFECT ON ACTIVATED BLEOMYCIN, The FASEB journal, 9(6), 1995, pp. 1492-1492
STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INHIBITION OF TYPE-1 AND 2 HUMAN5-ALPHA-REDUCTASE AND HUMAN ADRENAL 3-BETA-HYDROXY-DELTA(5)-STEROID DEHYDROGENASE 3-KETO-DELTA(5)-STEROID ISOMERASE BY 6-AZAANDROST-4-EN-3-ONES - OPTIMIZATION OF THE C17 SUBSTITUENT/
Authors: FRYE SV HAFFNER CD MALONEY PR HINER RN DORSEY GF NOE RA UNWALLA RJ BATCHELOR KW BRAMSON HN STUART JD SCHWEIKER SL VANAMOLD J BICKETT DM MOSS ML TIAN GC LEE FW TIPPIN TK JAMES MK GRIZZLE MK LONG JE CROOM DK
Citation: Sv. Frye et al., STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INHIBITION OF TYPE-1 AND 2 HUMAN5-ALPHA-REDUCTASE AND HUMAN ADRENAL 3-BETA-HYDROXY-DELTA(5)-STEROID DEHYDROGENASE 3-KETO-DELTA(5)-STEROID ISOMERASE BY 6-AZAANDROST-4-EN-3-ONES - OPTIMIZATION OF THE C17 SUBSTITUENT/, Journal of medicinal chemistry, 38(14), 1995, pp. 2621-2627
MECHANISM OF TIME-DEPENDENT INHIBITION OF 5-ALPHA-REDUCTASES BY DELTA(1)-4-AZASTEROIDS - TOWARD PERFECTION OF RATES OF TIME-DEPENDENT INHIBITION BY USING LIGAND-BINDING ENERGIES
Authors: TIAN GC MOOK RA MOSS ML FRYE SV
Citation: Gc. Tian et al., MECHANISM OF TIME-DEPENDENT INHIBITION OF 5-ALPHA-REDUCTASES BY DELTA(1)-4-AZASTEROIDS - TOWARD PERFECTION OF RATES OF TIME-DEPENDENT INHIBITION BY USING LIGAND-BINDING ENERGIES, Biochemistry, 34(41), 1995, pp. 13453-13459
CHEMICAL MECHANISM OF THE COVALENT MODIFICATION OF 5-ALPHA-REDUCTASESBY FINASTERIDE AS PROBED BY SECONDARY TRITIUM ISOTOPE EFFECTS
Authors: TIAN GC CHEN SY FACCHINE KL PRAKASH SR
Citation: Gc. Tian et al., CHEMICAL MECHANISM OF THE COVALENT MODIFICATION OF 5-ALPHA-REDUCTASESBY FINASTERIDE AS PROBED BY SECONDARY TRITIUM ISOTOPE EFFECTS, Journal of the American Chemical Society, 117(8), 1995, pp. 2369-2370
OXYGEN-ISOTOPE EFFECT ON ACTIVATED BLEOMYCIN STABILITY
Authors: BURGER RM TIAN GC DRLICA K
Citation: Rm. Burger et al., OXYGEN-ISOTOPE EFFECT ON ACTIVATED BLEOMYCIN STABILITY, Journal of the American Chemical Society, 117(3), 1995, pp. 1167-1168
6-AZASTEROIDS - STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INHIBITION OF TYPE-1 AND TYPE-2 HUMAN 5-ALPHA-REDUCTASE AND HUMAN ADRENAL 3-BETA-HYDROXY-DELTA(5)-STEROID DEHYDROGENASE 3-KETO-DELTA(5)-STEROID ISOMERASE
Authors: FRYE SV HAFFNER CD MALONEY PR MOOK RA DORSEY GF HINER RN CRIBBS CM WHEELER TN RAY JA ANDREWS RC BATCHELOR KW BRAMSON HN STUART JD SCHWEIKER SL VANARNOLD J CROOM S BICKETT DM MOSS ML TIAN GC UNWALLA RJ LEE FW TIPPIN TK JAMES MK GRIZZLE MK LONG JE SCHUSTER SV
Citation: Sv. Frye et al., 6-AZASTEROIDS - STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INHIBITION OF TYPE-1 AND TYPE-2 HUMAN 5-ALPHA-REDUCTASE AND HUMAN ADRENAL 3-BETA-HYDROXY-DELTA(5)-STEROID DEHYDROGENASE 3-KETO-DELTA(5)-STEROID ISOMERASE, Journal of medicinal chemistry, 37(15), 1994, pp. 2352-2360
BUTYLCARBAMOYL)-4-AZA-5-ALPHA-ANDROSTAN-1-EN-3-ONE IS AN ACTIVE-SITE-DIRECTED SLOW TIME-DEPENDENT INHIBITOR OF HUMAN STEROID 5-ALPHA-REDUCTASE-1
Authors: TIAN GC STUART JD MOSS ML DOMANICO PL BRAMSON HN PATEL IR KADWELL SH OVERTON LK KOST TA MOOK RA FRYE SV BATCHELOR KW WISEMAN JS
Citation: Gc. Tian et al., BUTYLCARBAMOYL)-4-AZA-5-ALPHA-ANDROSTAN-1-EN-3-ONE IS AN ACTIVE-SITE-DIRECTED SLOW TIME-DEPENDENT INHIBITOR OF HUMAN STEROID 5-ALPHA-REDUCTASE-1, Biochemistry, 33(8), 1994, pp. 2291-2296
O-18 KINETIC ISOTOPE EFFECTS IN THE DOPAMINE BETA-MONOOXYGENASE REACTION - EVIDENCE FOR A NEW CHEMICAL MECHANISM IN METALLOMONOOXYGENASES (VOL 33 PG 226, 1994)
Authors: TIAN GC BERRY JA KLINMAN JP
Citation: Gc. Tian et al., O-18 KINETIC ISOTOPE EFFECTS IN THE DOPAMINE BETA-MONOOXYGENASE REACTION - EVIDENCE FOR A NEW CHEMICAL MECHANISM IN METALLOMONOOXYGENASES (VOL 33 PG 226, 1994), Biochemistry, 33(48), 1994, pp. 14650-14650
O-18 KINETIC ISOTOPE EFFECTS IN THE DOPAMINE BETA-MONOOXYGENASE REACTION - EVIDENCE FOR A NEW CHEMICAL MECHANISM IN NONHEME METALLOMONOOXYGENASES
Authors: TIAN GC BERRY JA KLINMAN JP
Citation: Gc. Tian et al., O-18 KINETIC ISOTOPE EFFECTS IN THE DOPAMINE BETA-MONOOXYGENASE REACTION - EVIDENCE FOR A NEW CHEMICAL MECHANISM IN NONHEME METALLOMONOOXYGENASES, Biochemistry, 33(1), 1994, pp. 226-234
6-AZASTEROIDS - POTENT DUAL INHIBITORS OF HUMAN TYPE-1 AND 2 STEROID 5-ALPHA-REDUCTASE
Authors: FRYE SV HAFFNER CD MALONEY PR MOOK RA HINER RN BATCHELOR KW BRAMSON HN STUART JD SCHWEIKER SL VANARNOLD J BICKETT DM MOSS ML TIAN GC UNWALLA RJ LEE FW TIPPIN TK JAMES MK GRIZZLE MK LONG JE SCHUSTER SV DORSEY GF
Citation: Sv. Frye et al., 6-AZASTEROIDS - POTENT DUAL INHIBITORS OF HUMAN TYPE-1 AND 2 STEROID 5-ALPHA-REDUCTASE, Journal of medicinal chemistry, 36(26), 1993, pp. 4313-4315
DISCRIMINATION BETWEEN O-16 AND O-18 IN OXYGEN-BINDING TO THE REVERSIBLE OXYGEN CARRIERS HEMOGLOBIN, MYOGLOBIN, HEMERYTHRIN, AND HEMOCYANIN- A NEW PROBE FOR OXYGEN-BINDING AND REDUCTIVE ACTIVATION BY PROTEINS
Authors: TIAN GC KLINMAN JP
Citation: Gc. Tian et Jp. Klinman, DISCRIMINATION BETWEEN O-16 AND O-18 IN OXYGEN-BINDING TO THE REVERSIBLE OXYGEN CARRIERS HEMOGLOBIN, MYOGLOBIN, HEMERYTHRIN, AND HEMOCYANIN- A NEW PROBE FOR OXYGEN-BINDING AND REDUCTIVE ACTIVATION BY PROTEINS, Journal of the American Chemical Society, 115(20), 1993, pp. 8891-8897
Risultati: 1-16 |