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Results: 1-21 |
Results: 21
ANXIOLYTIC AND SIDE-EFFECT PROFILE OF LY354740 - A POTENT, HIGHLY SELECTIVE, ORALLY-ACTIVE AGONIST FOR GROUP-II METABOTROPIC GLUTAMATE RECEPTORS
Authors: HELTON DR TIZZANO JP MONN JA SCHOEPP DD KALLMAN MJ
Citation: Dr. Helton et al., ANXIOLYTIC AND SIDE-EFFECT PROFILE OF LY354740 - A POTENT, HIGHLY SELECTIVE, ORALLY-ACTIVE AGONIST FOR GROUP-II METABOTROPIC GLUTAMATE RECEPTORS, The Journal of pharmacology and experimental therapeutics, 284(2), 1998, pp. 651-660
2-SUBSTITUTED MINO-2-((1SR,2SR)-2-CARBOXYCYCLOPROP-1-YL)GLYCINES AS POTENT AND SELECTIVE ANTAGONISTS OF GROUP-II METABOTROPIC GLUTAMATE RECEPTORS - 2 - EFFECTS OF AROMATIC-SUBSTITUTION, PHARMACOLOGICAL CHARACTERIZATION, AND BIOAVAILABILITY
Authors: ORNSTEIN PL BLEISCH TJ ARNOLD MB KENNEDY JH WRIGHT RA JOHNSON BG TIZZANO JP HELTON DR KALLMAN MJ SCHOEPP DD HERIN M
Citation: Pl. Ornstein et al., 2-SUBSTITUTED MINO-2-((1SR,2SR)-2-CARBOXYCYCLOPROP-1-YL)GLYCINES AS POTENT AND SELECTIVE ANTAGONISTS OF GROUP-II METABOTROPIC GLUTAMATE RECEPTORS - 2 - EFFECTS OF AROMATIC-SUBSTITUTION, PHARMACOLOGICAL CHARACTERIZATION, AND BIOAVAILABILITY, Journal of medicinal chemistry, 41(3), 1998, pp. 358-378
LY354740 - A METABOTROPIC GLUTAMATE-RECEPTOR AGONIST WHICH AMELIORATES SYMPTOMS OF NICOTINE WITHDRAWAL IN RATS
Authors: HELTON DR TIZZANO JP MONN JA SCHOEPP DD KALLMAN MJ
Citation: Dr. Helton et al., LY354740 - A METABOTROPIC GLUTAMATE-RECEPTOR AGONIST WHICH AMELIORATES SYMPTOMS OF NICOTINE WITHDRAWAL IN RATS, Neuropharmacology, 36(11-12), 1997, pp. 1511-1516
DESIGN, SYNTHESIS, AND PHARMACOLOGICAL CHARACTERIZATION OF (-2-AMINOBICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID (LY354740) - A POTENT, SELECTIVE, AND ORALLY-ACTIVE GROUP-2 METABOTROPIC GLUTAMATE-RECEPTOR AGONIST POSSESSING ANTICONVULSANT AND ANXIOLYTIC PROPERTIES())
Authors: MONN JA VALLI MJ MASSEY SM WRIGHT RA SALHOFF CR JOHNSON BG HOWE T ALT CA RHODES GA ROBEY RL GRIFFEY KR TIZZANO JP KALLMAN MJ HELTON DR SCHOEPP DD
Citation: Ja. Monn et al., DESIGN, SYNTHESIS, AND PHARMACOLOGICAL CHARACTERIZATION OF (-2-AMINOBICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID (LY354740) - A POTENT, SELECTIVE, AND ORALLY-ACTIVE GROUP-2 METABOTROPIC GLUTAMATE-RECEPTOR AGONIST POSSESSING ANTICONVULSANT AND ANXIOLYTIC PROPERTIES()), Journal of medicinal chemistry, 40(4), 1997, pp. 528-537
TIME-DEPENDENT EFFECTS OF NICOTINE ADMINISTRATION AND CESSATION ON COGNITIVE PERFORMANCE
Authors: HELTON DR KALLMAN MJ JOHNSON JA TIZZANO JP
Citation: Dr. Helton et al., TIME-DEPENDENT EFFECTS OF NICOTINE ADMINISTRATION AND CESSATION ON COGNITIVE PERFORMANCE, Addiction, 91(1), 1996, pp. 140-140
SELECTIVE PROTECTION AGAINST AMPA-EVOKED AND KAINATE-EVOKED NEUROTOXICITY BY ZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (LY293558) AND ITS RACEMATE (LY215490)
Authors: SCHOEPP DD SALHOFF CR FUSON KS SACAAN AI TIZZANO JP ORNSTEIN PL MAY PC
Citation: Dd. Schoepp et al., SELECTIVE PROTECTION AGAINST AMPA-EVOKED AND KAINATE-EVOKED NEUROTOXICITY BY ZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID (LY293558) AND ITS RACEMATE (LY215490), Journal of neural transmission, 103(8-9), 1996, pp. 905-916
SYNTHESIS OF A SERIES OF ARYL KAINIC ACID ANALOGS AND EVALUATION IN CELLS STABLY EXPRESSING THE KAINATE RECEPTOR HUMGLUR6
Authors: CANTRELL BE ZIMMERMAN DM MONN JA KAMBOJ RK HOO KH TIZZANO JP PULLAR IA FARRELL LN BLEAKMAN D
Citation: Be. Cantrell et al., SYNTHESIS OF A SERIES OF ARYL KAINIC ACID ANALOGS AND EVALUATION IN CELLS STABLY EXPRESSING THE KAINATE RECEPTOR HUMGLUR6, Journal of medicinal chemistry, 39(19), 1996, pp. 3617-3624
SYNTHESIS OF THE 4 ISOMERS OF 4-AMINOPYRROLIDINE-2,4-DICARBOXYLATE - IDENTIFICATION OF A POTENT, HIGHLY SELECTIVE, AND SYSTEMICALLY-ACTIVE AGONIST FOR METABOTROPIC GLUTAMATE RECEPTORS NEGATIVELY COUPLED TO ADENYLATE-CYCLASE
Authors: MONN JA VALLI MJ JOHNSON BG SALHOFF CR WRIGHT RA HOWE T BOND A LODGE D SPANGLE LA PASCHAL JW CAMPBELL JB GRIFFEY K TIZZANO JP SCHOEPP DD
Citation: Ja. Monn et al., SYNTHESIS OF THE 4 ISOMERS OF 4-AMINOPYRROLIDINE-2,4-DICARBOXYLATE - IDENTIFICATION OF A POTENT, HIGHLY SELECTIVE, AND SYSTEMICALLY-ACTIVE AGONIST FOR METABOTROPIC GLUTAMATE RECEPTORS NEGATIVELY COUPLED TO ADENYLATE-CYCLASE, Journal of medicinal chemistry, 39(15), 1996, pp. 2990-3000
REVERSIBLE AND IRREVERSIBLE NEURONAL INJURY-INDUCED BY INTRAHIPPOCAMPAL INFUSION OF THE MGLUR AGONIST 1S,3R-ACPD IN THE RAT
Authors: SCHOEPP DD TIZZANO JP WRIGHT RA FIX AS
Citation: Dd. Schoepp et al., REVERSIBLE AND IRREVERSIBLE NEURONAL INJURY-INDUCED BY INTRAHIPPOCAMPAL INFUSION OF THE MGLUR AGONIST 1S,3R-ACPD IN THE RAT, Neurodegeneration, 4(1), 1995, pp. 71-80
BEHAVIORAL-EFFECTS OF COMPOUNDS ACTING AT SUBTYPES OF METABOTROPIC GLUTAMATE RECEPTORS
Authors: SCHOEPP DD MONN JA TIZZANO JP
Citation: Dd. Schoepp et al., BEHAVIORAL-EFFECTS OF COMPOUNDS ACTING AT SUBTYPES OF METABOTROPIC GLUTAMATE RECEPTORS, Behavioural pharmacology, 6(5-6), 1995, pp. 632-632
INTRACEREBRAL INJECTIONS OF METABOTROPIC GLUTAMATE-RECEPTOR AGONISTS CAN INDUCE OR PROTECT AGAINST LIMBIC SEIZURES IN MICE
Authors: TIZZANO JP GRIFFEY KI VALLI MJ HELTON DR KALLMAN MJ SCHOEPP DD MONN JA
Citation: Jp. Tizzano et al., INTRACEREBRAL INJECTIONS OF METABOTROPIC GLUTAMATE-RECEPTOR AGONISTS CAN INDUCE OR PROTECT AGAINST LIMBIC SEIZURES IN MICE, Behavioural pharmacology, 6(5-6), 1995, pp. 633-634
PROGRESSIVE RETINAL TOXICITY IN NEONATAL RATS TREATED WITH D,L-2-AMINO-3-PHOSPHONOPROPIONATE (D,L-AP3)
Authors: FIX AS HORN JW HALL RL JOHNSON JA TIZZANO JP
Citation: As. Fix et al., PROGRESSIVE RETINAL TOXICITY IN NEONATAL RATS TREATED WITH D,L-2-AMINO-3-PHOSPHONOPROPIONATE (D,L-AP3), Veterinary pathology, 32(5), 1995, pp. 521-531
IN-VITRO AND IN-VIVO ANTAGONISM OF AMPA RECEPTOR ACTIVATION BY ZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
Authors: SCHOEPP DD LODGE D BLEAKMAN D LEANDER JD TIZZANO JP WRIGHT RA PALMER AJ SALHOFF CR ORNSTEIN PL
Citation: Dd. Schoepp et al., IN-VITRO AND IN-VIVO ANTAGONISM OF AMPA RECEPTOR ACTIVATION BY ZOLE-5-YL)ETHYL]DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID, Neuropharmacology, 34(9), 1995, pp. 1159-1168
INDUCTION OR PROTECTION OF LIMBIC SEIZURES IN MICE BY MGLUR SUBTYPE-SELECTIVE AGONISTS
Authors: TIZZANO JP GRIFFEY KI SCHOEPP DD
Citation: Jp. Tizzano et al., INDUCTION OR PROTECTION OF LIMBIC SEIZURES IN MICE BY MGLUR SUBTYPE-SELECTIVE AGONISTS, Neuropharmacology, 34(8), 1995, pp. 1063-1067
BLOCKADE OF THE 2ND-MESSENGER FUNCTIONS OF THE GLUTAMATE METABOTROPICRECEPTOR IS ASSOCIATED WITH DEGENERATIVE CHANGES IN THE RETINA AND BRAIN OF IMMATURE RODENTS
Authors: PRICE MT ROMANO C FIX AS TIZZANO JP OLNEY JW
Citation: Mt. Price et al., BLOCKADE OF THE 2ND-MESSENGER FUNCTIONS OF THE GLUTAMATE METABOTROPICRECEPTOR IS ASSOCIATED WITH DEGENERATIVE CHANGES IN THE RETINA AND BRAIN OF IMMATURE RODENTS, Neuropharmacology, 34(8), 1995, pp. 1069-1079
H-TETRAZOL-5-YL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID, A NOVEL, COMPETITIVE, SYSTEMICALLY ACTIVE NMDA AND AMPA RECEPTOR ANTAGONIST
Authors: ORNSTEIN PL ARNOLD MB ALLEN NK LEANDER JD TIZZANO JP LODGE D SCHOEPP DD
Citation: Pl. Ornstein et al., H-TETRAZOL-5-YL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID, A NOVEL, COMPETITIVE, SYSTEMICALLY ACTIVE NMDA AND AMPA RECEPTOR ANTAGONIST, Journal of medicinal chemistry, 38(25), 1995, pp. 4885-4890
NICOTINE WITHDRAWAL - A BEHAVIORAL-ASSESSMENT USING SCHEDULE-CONTROLLED RESPONDING, LOCOMOTOR-ACTIVITY, AND SENSORIMOTOR REACTIVITY
Authors: HELTON DR MODLIN DL TIZZANO JP RASMUSSEN K
Citation: Dr. Helton et al., NICOTINE WITHDRAWAL - A BEHAVIORAL-ASSESSMENT USING SCHEDULE-CONTROLLED RESPONDING, LOCOMOTOR-ACTIVITY, AND SENSORIMOTOR REACTIVITY, Psychopharmacology, 113(2), 1993, pp. 205-210
INTRACEREBRAL 1S,3R-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID (1S,3R-ACPD) PRODUCES LIMBIC SEIZURES THAT ARE NOT BLOCKED BY IONOTROPIC GLUTAMATE-RECEPTOR ANTAGONISTS
Authors: TIZZANO JP GRIFFEY KI JOHNSON JA FIX AS HELTON DR SCHOEPP DD
Citation: Jp. Tizzano et al., INTRACEREBRAL 1S,3R-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID (1S,3R-ACPD) PRODUCES LIMBIC SEIZURES THAT ARE NOT BLOCKED BY IONOTROPIC GLUTAMATE-RECEPTOR ANTAGONISTS, Neuroscience letters, 162(1-2), 1993, pp. 12-16
SEIZURES AND BRAIN INJURY IN NEONATAL RATS INDUCED BY 1S,3R-ACPD, A METABOTROPIC GLUTAMATE-RECEPTOR AGONIST
Authors: MCDONALD JW FIX AS TIZZANO JP SCHOEPP DD
Citation: Jw. Mcdonald et al., SEIZURES AND BRAIN INJURY IN NEONATAL RATS INDUCED BY 1S,3R-ACPD, A METABOTROPIC GLUTAMATE-RECEPTOR AGONIST, The Journal of neuroscience, 13(10), 1993, pp. 4445-4455
NEONATAL EXPOSURE TO D,L-2-AMINO-3-PHOSPHONOPROPIONATE (D,L-AP3) PRODUCES LESIONS IN THE EYE AND OPTIC-NERVE OF ADULT-RATS
Authors: FIX AS SCHOEPP DD OLNEY JW VESTRE WA GRIFFEY KI JOHNSON JA TIZZANO JP
Citation: As. Fix et al., NEONATAL EXPOSURE TO D,L-2-AMINO-3-PHOSPHONOPROPIONATE (D,L-AP3) PRODUCES LESIONS IN THE EYE AND OPTIC-NERVE OF ADULT-RATS, Developmental brain research, 75(2), 1993, pp. 223-233
DEVELOPMENTAL TOXICITY OF GEMCITABINE, AN ANTIMETABOLITE ONCOLYTIC, ADMINISTERED DURING GESTATION TO CD-1 MICE
Authors: EUDALY JA TIZZANO JP HIGDON GL TODD GC
Citation: Ja. Eudaly et al., DEVELOPMENTAL TOXICITY OF GEMCITABINE, AN ANTIMETABOLITE ONCOLYTIC, ADMINISTERED DURING GESTATION TO CD-1 MICE, Teratology, 48(4), 1993, pp. 365-381
Risultati: 1-21 |