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Results: 1-25/27
Authors:
KUMAZAWA E
JIMBO T
OCHI Y
TOHGO A
Citation: E. Kumazawa et al., POTENT AND BROAD ANTITUMOR EFFECTS OF DX-8951F, A WATER-SOLUBLE CAMPTOTHECIN DERIVATIVE, AGAINST VARIOUS HUMAN TUMORS XENOGRAFTED IN NUDE-MICE, Cancer chemotherapy and pharmacology, 42(3), 1998, pp. 210-220
Authors:
IKEHATA F
SATOH J
NATA K
TOHGO A
NAKAZAWA T
KATO I
KOBAYASHI S
AKIYAMA T
TAKASAWA S
TOYOTA T
OKAMOTO H
Citation: F. Ikehata et al., AUTOANTIBODIES AGAINST CD38 (ADP RIBOSYL CYCLASE CYCLIC ADP RIBOSE HYDROLASE) THAT IMPAIR GLUCOSE-INDUCED INSULIN-SECRETION IN NONINSULIN-DEPENDENT DIABETES PATIENTS, The Journal of clinical investigation, 102(2), 1998, pp. 395-401
Authors:
TAKASAWA S
AKIYAMA T
NATA K
KUROKI M
TOHGO A
NOGUCHI N
KOBAYASHI S
KATO I
KATADA T
OKAMOTO H
Citation: S. Takasawa et al., CYCLIC ADP-RIBOSE AND INOSITOL 1,4,5-TRISPHOSPHATE AS ALTERNATE 2ND MESSENGERS FOR INTRACELLULAR CA2-CELLS( MOBILIZATION IN NORMAL AND DIABETIC BETA), The Journal of biological chemistry, 273(5), 1998, pp. 2497-2500
Authors:
YAGUI K
SHIMADA F
MIMURA M
HASHIMOTO N
SUZUKI Y
TOKUYAMA Y
NATA K
TOHGO A
IKEHATA F
TAKASAWA S
OKAMOTO H
MAKINO H
SAITO Y
KANATSUKA A
Citation: K. Yagui et al., A MISSENSE MUTATION IN THE CD38 GENE, A NOVEL FACTOR FOR INSULIN-SECRETION - ASSOCIATION WITH TYPE-II DIABETES-MELLITUS IN JAPANESE SUBJECTS AND EVIDENCE OF ABNORMAL FUNCTION WHEN EXPRESSED IN-VITRO, Diabetologia, 41(9), 1998, pp. 1024-1028
Authors:
TAKIGUCHI S
KUMAZAWA E
SHIMAZOE T
TOHGO A
KONO A
Citation: S. Takiguchi et al., ANTITUMOR EFFECT OF DX-8951, A NOVEL CAMPTOTHECIN ANALOG, ON HUMAN PANCREATIC TUMOR-CELLS AND THEIR CPT-11-RESISTANT VARIANTS CULTURED IN-VITRO AND XENOGRAFTED INTO NUDE-MICE, Japanese journal of cancer research, 88(8), 1997, pp. 760-769
Authors:
KUMAZAWA E
JIMBO T
AKIMOTO T
JOTO N
TOHGO A
Citation: E. Kumazawa et al., ANTITUMOR EFFECT OF DT-5461, A LIPID-A DERIVATIVE, AGAINST HUMAN TUMOR XENOGRAFTS IS MEDIATED BY INTRATUMORAL PRODUCTION OF TUMOR-NECROSIS-FACTOR AND AFFECTED BY HOST IMMUNOSUPPRESSIVE FACTORS IN NUDE-MICE, Cancer investigation, 15(6), 1997, pp. 522-530
Authors:
NATA K
TAKAMURA T
KARASAWA T
KUMAGAI T
HASHIOKA W
TOHGO A
YONEKURA H
TAKASAWA S
NAKAMURA S
OKAMOTO H
Citation: K. Nata et al., HUMAN GENE ENCODING CD38 (ADP-RIBOSYL CYCLASE CYCLIC ADP-RIBOSE HYDROLASE) - ORGANIZATION, NUCLEOTIDE-SEQUENCE AND ALTERNATIVE SPLICING/, Gene, 186(2), 1997, pp. 285-292
Authors:
TOHGO A
MUNAKATA H
TAKASAWA S
NATA K
AKIYAMA T
HAYASHI N
OKAMOTO H
Citation: A. Tohgo et al., LYSINE-129 OF CD38 (ADP-RIBOSYL CYCLASE CYCLIC ADP-RIBOSE HYDROLASE) PARTICIPATES IN THE BINDING OF ATP TO INHIBIT THE CYCLIC ADP-RIBOSE HYDROLASE/, The Journal of biological chemistry, 272(7), 1997, pp. 3879-3882
Authors:
NOGUCHI N
TAKASAWA S
NATA K
TOHGO A
KATO I
IKEHATA F
YONEKURA H
OKAMOTO H
Citation: N. Noguchi et al., CYCLIC ADP-RIBOSE BINDS TO FK506-BINDING PROTEIN-12.6 TO RELEASE CA2+FROM ISLET MICROSOMES, The Journal of biological chemistry, 272(6), 1997, pp. 3133-3136
Authors:
JOTO N
ISHII M
MINAMI M
KUGA H
MITSUI I
TOHGO A
Citation: N. Joto et al., DX-8951F, A WATER-SOLUBLE CAMPTOTHECIN ANALOG, EXHIBITS POTENT ANTITUMOR-ACTIVITY AGAINST A HUMAN LUNG-CANCER CELL-LINE AND ITS SN-38-RESISTANT VARIANT, International journal of cancer, 72(4), 1997, pp. 680-686
Authors:
OKAMOTO H
IKEHATA F
SATOH J
TAKASAWA S
TOHGO A
NATA K
KATO I
TOYOTA T
Citation: H. Okamoto et al., AUTOANTIBODIES AGAINST CD38 (ADP-RIBOSYL CYCLASE CYCLIC ADP-RIBOSE HYDROLASE) IN DIABETIC-PATIENTS, Diabetologia, 40, 1997, pp. 420-420
Authors:
OKAMOTO H
NOGUCHI N
AKIYAMA T
TAKASAWA S
NATA K
TOHGO A
KATO I
IKEHATA F
Citation: H. Okamoto et al., IDENTIFICATION OF CYCLIC ADP-RIBOSE-BINDING PROTEIN IN RYANODINE RECEPTOR OF ISLET MICROSOMES, Diabetes, 46, 1997, pp. 820-820
Authors:
JIMBO T
AKIMOTO T
TOHGO A
Citation: T. Jimbo et al., SYSTEMIC ADMINISTRATION OF A SYNTHETIC LIPID-A DERIVATIVE, DT-5461A, REDUCES TUMOR BLOOD-FLOW THROUGH ENDOGENOUS TNF PRODUCTION IN HEPATIC CANCER MODEL OF VX2 CARCINOMA IN RABBITS, Anticancer research, 16(1), 1996, pp. 359-364
Authors:
KUMAZAWA E
AKIMOTO T
KITA Y
JIMBO T
JOTO N
TOHGO A
Citation: E. Kumazawa et al., INTRATUMORAL PRODUCTION OF TUMOR-NECROSIS-FACTOR AUGMENTED BY ENDOGENOUS INTERFERONS RESULTS IN POTENT ANTITUMOR EFFECTS OF DT-5461, A SYNTHETIC LIPID-A ANALOG, Journal of immunotherapy with emphasis on tumor immunology, 17(3), 1995, pp. 141-150
Authors:
NATA K
SUGIMOTO T
TOHGO A
TAKAMURA T
NOGUCHI N
MATSUOKA A
NUMAKUNAI T
SHIKAMA K
YONEKURA H
TAKASAWA S
OKAMOTO H
Citation: K. Nata et al., THE STRUCTURE OF THE APLYSIA-KURODAI GENE ENCODING ADP-RIBOSYL CYCLASE, A 2ND-MESSENGER ENZYME, Gene, 158(2), 1995, pp. 213-218
Authors:
JIMBO T
AKIMOTO T
TOHGO A
Citation: T. Jimbo et al., EFFECT OF COMBINED ADMINISTRATION OF A SYNTHETIC LOW TOXICITY LIPID-ADERIVATIVE, DT-5461A, AND INDOMETHACIN IN VARIOUS EXPERIMENTAL TUMOR-MODELS OF COLON-26 CARCINOMA IN MICE, Cancer immunology and immunotherapy, 40(1), 1995, pp. 10-16
Authors:
NAKAGAWARA K
MORI M
TAKASAWA S
NATA K
TAKAMURA T
BERLOVA A
TOHGO A
KARASAWA T
YONEKURA H
TAKEUCHI T
OKAMOTO H
Citation: K. Nakagawara et al., ASSIGNMENT OF CD38, THE GENE ENCODING HUMAN-LEUKOCYTE ANTIGEN CD38 (ADP-RIBOSYL CYCLASE CYCLIC ADP-RIBOSE HYDROLASE), TO CHROMOSOME 4P15, Cytogenetics and cell genetics, 69(1-2), 1995, pp. 38-39
Authors:
OKAMOTO H
TAKASAWA S
TOHGO A
Citation: H. Okamoto et al., NEW ASPECTS OF THE PHYSIOLOGICAL SIGNIFICANCE OF NAD, POLY ADP-RIBOSEAND CYCLIC ADP-RIBOSE, Biochimie, 77(5), 1995, pp. 356-363
Authors:
AKIMOTO T
KUMAZAWA E
JIMBO T
JOTO N
TOHGO A
Citation: T. Akimoto et al., DT-5461A, AN ANTITUMOR SYNTHETIC LIPID-A ANALOG, CAUSES SELECTIVE BLOOD-FLOW REDUCTION IN TUMOR-TISSUE, Anticancer research, 15(1), 1995, pp. 105-107
Authors:
TAKASAWA S
ISHIDA A
NATA K
NAKAGAWA K
NOGUCHI N
TOHGO A
KATO I
YONEKURA H
FUJISAWA H
OKAMOTO H
Citation: S. Takasawa et al., REQUIREMENT OF CALMODULIN-DEPENDENT PROTEIN-KINASE-II IN CYCLIC ADP-RIBOSE-MEDIATED INTRACELLULAR CA2+ MOBILIZATION, The Journal of biological chemistry, 270(51), 1995, pp. 30257-30259
Authors:
JOTO N
AKIMOTO T
SOMEYA K
TOHGO A
Citation: N. Joto et al., PRODUCTION OF TUMOR-NECROSIS-FACTOR INDUCED BY SYNTHETIC LOW-TOXICITYLIPID-A ANALOG, DT-5461A, IS MEDIATED BY LPS RECEPTOR-SITES AND TYROSINE KINASE-MAP KINASE SIGNALING PATHWAY IN MURINE MACROPHAGES, Cellular immunology, 160(1), 1995, pp. 1-7
Authors:
AKIMOTO T
KUMAZAWA E
JIMBO T
JOTO N
TOHGO A
Citation: T. Akimoto et al., ANTITUMOR EFFECT OF DT-5461A, A SYNTHETIC LOW-TOXICITY LIPID-A ANALOG, INVOLVES ENDOGENOUS TUMOR-NECROSIS-FACTOR INDUCTION SUBSEQUENT TO MACROPHAGE ACTIVATION, International journal of immunopharmacology, 16(11), 1994, pp. 887-893
Authors:
KOGUMA T
TAKASAWA S
TOHGO A
KARASAWA T
FURUYA Y
YONEKURA H
OKAMOTO H
Citation: T. Koguma et al., CLONING AND CHARACTERIZATION OF CDNA-ENCODING RAT ADP-RIBOSYL CYCLASECYCLIC ADP-RIBOSE HYDROLASE (HOMOLOG TO HUMAN CD38) FROM ISLETS OF LANGERHANS, Biochimica et biophysica acta. Molecular cell research, 1223(1), 1994, pp. 160-162
Authors:
TOHGO A
TAKASAWA S
NOGUCHI N
KOGUMA T
NATA K
SUGIMOTO T
FURUYA Y
YONEKURA H
OKAMOTO H
Citation: A. Tohgo et al., ESSENTIAL CYSTEINE RESIDUES FOR CYCLIC ADP-RIBOSE SYNTHESIS AND HYDROLYSIS BY CD38, The Journal of biological chemistry, 269(46), 1994, pp. 28555-28557
Authors:
TOHGO A
TAKASAWA S
MUNAKATA H
YONEKURA H
HAYASHI N
OKAMOTO H
Citation: A. Tohgo et al., STRUCTURAL DETERMINATION AND CHARACTERIZATION OF A 40 KDA PROTEIN ISOLATED FROM RAT 40-S-RIBOSOMAL-SUBUNIT, FEBS letters, 340(1-2), 1994, pp. 133-138