AAAAAA

   
Results: 1-25 | 26-38
Results: 1-25/38
GILAV,EMANUEL HONORARY ISSUE OF CHIRALITY
Authors: TRAGER WF
Citation: Wf. Trager, GILAV,EMANUEL HONORARY ISSUE OF CHIRALITY, Chirality, 10(5), 1998, pp. 371-372
OXIDATION OF ACETAMINOPHEN TO ITS TOXIC QUINONE IMINE AND NONTOXIC CATECHOL METABOLITES BY BACULOVIRUS-EXPRESSED AND PURIFIED HUMAN CYTOCHROMES P450 2E1 AND 2A6
Authors: CHEN WQ KOENIGS LL THOMPSON SJ PETER RM PETTIE AE TRAGER WF NELSON SD
Citation: Wq. Chen et al., OXIDATION OF ACETAMINOPHEN TO ITS TOXIC QUINONE IMINE AND NONTOXIC CATECHOL METABOLITES BY BACULOVIRUS-EXPRESSED AND PURIFIED HUMAN CYTOCHROMES P450 2E1 AND 2A6, Chemical research in toxicology, 11(4), 1998, pp. 295-301
SELECTIVELY DEUTERATED WARFARIN - SUBSTRATE PROBE FOR THE MECHANISM OF AROMATIC HYDROXYLATION CATALYZED BY CYTOCHROME-P450
Authors: DARBYSHIRE JF IYER KR GROGAN J KORZEKWA KR TRAGER WF
Citation: Jf. Darbyshire et al., SELECTIVELY DEUTERATED WARFARIN - SUBSTRATE PROBE FOR THE MECHANISM OF AROMATIC HYDROXYLATION CATALYZED BY CYTOCHROME-P450, The FASEB journal, 12(5), 1998, pp. 5567-5567
(R)-(-MENTHOFURAN IS A POTENT, MECHANISM-BASED INACTIVATOR OF HUMAN LIVER CYTOCHROME-P450 2A6())
Authors: KHOJASTEHBAKHT SC KOENIGS LL PETER RM TRAGER WF NELSON SD
Citation: Sc. Khojastehbakht et al., (R)-(-MENTHOFURAN IS A POTENT, MECHANISM-BASED INACTIVATOR OF HUMAN LIVER CYTOCHROME-P450 2A6()), Drug metabolism and disposition, 26(7), 1998, pp. 701-704
MECHANISM-BASED INACTIVATION OF CYTOCHROME-P450 2B1 BY 8-METHOXYPSORALEN AND SEVERAL OTHER FURANOCOUMARINS
Authors: KOENIGS LL TRAGER WF
Citation: Ll. Koenigs et Wf. Trager, MECHANISM-BASED INACTIVATION OF CYTOCHROME-P450 2B1 BY 8-METHOXYPSORALEN AND SEVERAL OTHER FURANOCOUMARINS, Biochemistry, 37(38), 1998, pp. 13184-13193
MECHANISM-BASED INACTIVATION OF P450 2A6 BY FURANOCOUMARINS
Authors: KOENIGS LL TRAGER WF
Citation: Ll. Koenigs et Wf. Trager, MECHANISM-BASED INACTIVATION OF P450 2A6 BY FURANOCOUMARINS, Biochemistry, 37(28), 1998, pp. 10047-10061
GENETIC ASSOCIATION BETWEEN SENSITIVITY TO WARFARIN AND EXPRESSION OFCYP2C9-ASTERISK-3
Authors: STEWARD DJ HAINING RL HENNE KR DAVIS G RUSHMORE TH TRAGER WF RETTIE AE
Citation: Dj. Steward et al., GENETIC ASSOCIATION BETWEEN SENSITIVITY TO WARFARIN AND EXPRESSION OFCYP2C9-ASTERISK-3, Pharmacogenetics, 7(5), 1997, pp. 361-367
ISOFORM-SELECTIVE MECHANISM-BASED INACTIVATION OF HUMAN P450 2A6 BY 8-METHOXYPSORALEN (8-MOP)
Authors: KOENIGS LL PETER RM THOMPSON SJ RETTIE AE TRAGER WF
Citation: Ll. Koenigs et al., ISOFORM-SELECTIVE MECHANISM-BASED INACTIVATION OF HUMAN P450 2A6 BY 8-METHOXYPSORALEN (8-MOP), The FASEB journal, 11(9), 1997, pp. 185-185
LACK OF EFFECT OF AZELASTINE AND KETOCONAZOLE COADMINISTRATION ON ELECTROCARDIOGRAPHIC PARAMETERS IN HEALTHY-VOLUNTEERS
Authors: MORGANROTH J LYNESS WH PERHACH JL MATHER GG HARR JE TRAGER WF LEVY RH ROSENBERG A
Citation: J. Morganroth et al., LACK OF EFFECT OF AZELASTINE AND KETOCONAZOLE COADMINISTRATION ON ELECTROCARDIOGRAPHIC PARAMETERS IN HEALTHY-VOLUNTEERS, Journal of clinical pharmacology, 37(11), 1997, pp. 1065-1072
MECHANISM-BASED INACTIVATION OF HUMAN LIVER CYTOCHROME-P450 2A6 BY 8-METHOXYPSORALEN
Authors: KOENIGS LL PETER RM THOMPSON SJ RETTIE AE TRAGER WF
Citation: Ll. Koenigs et al., MECHANISM-BASED INACTIVATION OF HUMAN LIVER CYTOCHROME-P450 2A6 BY 8-METHOXYPSORALEN, Drug metabolism and disposition, 25(12), 1997, pp. 1407-1415
INFLUENCE OF STIRIPENTOL ON CYTOCHROME P450-MEDIATED METABOLIC PATHWAYS IN HUMANS - IN-VITRO AND IN-VIVO COMPARISON AND CALCULATION OF IN-VIVO INHIBITION CONSTANTS
Authors: TRAN A REY E PONS G ROUSSEAU M DATHIS P OLIVE G MATHER GG BISHOP FE WURDEN CJ LABROO R TRAGER WF KUNZE KL THUMMEL KE VINCENT JC GILLARDIN JM LEPAGE F LEVY RH
Citation: A. Tran et al., INFLUENCE OF STIRIPENTOL ON CYTOCHROME P450-MEDIATED METABOLIC PATHWAYS IN HUMANS - IN-VITRO AND IN-VIVO COMPARISON AND CALCULATION OF IN-VIVO INHIBITION CONSTANTS, Clinical pharmacology and therapeutics, 62(5), 1997, pp. 490-504
LACK OF HUMAN CYP450 INHIBITION BY TIZANIDINE AND 2 MAJOR METABOLITES
Authors: MATHER GG HARR JH HARGREAVES JA TRAGER WF LEVY RH
Citation: Gg. Mather et al., LACK OF HUMAN CYP450 INHIBITION BY TIZANIDINE AND 2 MAJOR METABOLITES, Clinical pharmacology and therapeutics, 61(2), 1997, pp. 9-9
INTRAMOLECULAR ISOTOPE EFFECTS FOR BENZYLIC HYDROXYLATION OF ISOMERICXYLENES AND 4,4'-DIMETHYLBIPHENYL BY CYTOCHROME-P450 - RELATIONSHIP BETWEEN DISTANCE OF METHYL-GROUPS AND MASKING OF THE INTRINSIC ISOTOPE EFFECT
Authors: IYER KR JONES JP DARBYSHIRE JF TRAGER WF
Citation: Kr. Iyer et al., INTRAMOLECULAR ISOTOPE EFFECTS FOR BENZYLIC HYDROXYLATION OF ISOMERICXYLENES AND 4,4'-DIMETHYLBIPHENYL BY CYTOCHROME-P450 - RELATIONSHIP BETWEEN DISTANCE OF METHYL-GROUPS AND MASKING OF THE INTRINSIC ISOTOPE EFFECT, Biochemistry, 36(23), 1997, pp. 7136-7143
SELECTIVELY DEUTERATED WARFARIN - SUBSTRATE PROBE FOR THE MECHANISM OF AROMATIC HYDROXYLATION CATALYZED BY CYTOCHROME-P450
Authors: DARBYSHIRE JF IYER KR GROGAN J KORZEKWA KR TRAGER WF
Citation: Jf. Darbyshire et al., SELECTIVELY DEUTERATED WARFARIN - SUBSTRATE PROBE FOR THE MECHANISM OF AROMATIC HYDROXYLATION CATALYZED BY CYTOCHROME-P450, Drug metabolism and disposition, 24(9), 1996, pp. 1038-1045
FORMATION OF (R)-8-HYDROXYWARFARIN IN HUMAN LIVER-MICROSOMES - A NEW METABOLIC MARKER FOR THE (S)-MEPHENYTOIN HYDROXYLASE, P4502C19
Authors: WIENKERS LC WURDEN CJ STORCH E KUNZE KL RETTIE AE TRAGER WF
Citation: Lc. Wienkers et al., FORMATION OF (R)-8-HYDROXYWARFARIN IN HUMAN LIVER-MICROSOMES - A NEW METABOLIC MARKER FOR THE (S)-MEPHENYTOIN HYDROXYLASE, P4502C19, Drug metabolism and disposition, 24(5), 1996, pp. 610-614
WARFARIN-FLUCONAZOLE .1. INHIBITION OF THE HUMAN CYTOCHROME-P450-DEPENDENT METABOLISM OF WARFARIN BY FLUCONAZOLE - IN-VITRO STUDIES
Authors: KUNZE KL WIENKERS LC THUMMEL KE TRAGER WF
Citation: Kl. Kunze et al., WARFARIN-FLUCONAZOLE .1. INHIBITION OF THE HUMAN CYTOCHROME-P450-DEPENDENT METABOLISM OF WARFARIN BY FLUCONAZOLE - IN-VITRO STUDIES, Drug metabolism and disposition, 24(4), 1996, pp. 414-421
WARFARIN-FLUCONAZOLE .2. A METABOLICALLY BASED DRUG-INTERACTION - IN-VIVO STUDIES
Authors: BLACK DJ KUNZE KL WIENKERS LC GIDAL BE SEATON TL MCDONNELL ND EVANS JS BAUWENS E TRAGER WF
Citation: Dj. Black et al., WARFARIN-FLUCONAZOLE .2. A METABOLICALLY BASED DRUG-INTERACTION - IN-VIVO STUDIES, Drug metabolism and disposition, 24(4), 1996, pp. 422-428
WARFARIN-FLUCONAZOLE .2. A RATIONAL APPROACH TO MANAGEMENT OF A METABOLICALLY BASED DRUG-INTERACTION
Authors: KUNZE KL TRAGER WF
Citation: Kl. Kunze et Wf. Trager, WARFARIN-FLUCONAZOLE .2. A RATIONAL APPROACH TO MANAGEMENT OF A METABOLICALLY BASED DRUG-INTERACTION, Drug metabolism and disposition, 24(4), 1996, pp. 429-435
3-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP FOR INHIBITORS OF CYTOCHROME P4502C9
Authors: JONES JP HE MX TRAGER WF RETTIE AE
Citation: Jp. Jones et al., 3-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP FOR INHIBITORS OF CYTOCHROME P4502C9, Drug metabolism and disposition, 24(1), 1996, pp. 1-6
MECHANISMS FOR HIGH-DOSE WARFARIN THERAPY
Authors: MAO Z SHEDLOFSKY S GERMAN T WEDLUND PJ TRAGER WF
Citation: Z. Mao et al., MECHANISMS FOR HIGH-DOSE WARFARIN THERAPY, Clinical pharmacology and therapeutics, 59(2), 1996, pp. 80-80
ALLELIC VARIANTS OF HUMAN CYTOCHROME-P450 2C9 - BACULOVIRUS-MEDIATED EXPRESSION, PURIFICATION, STRUCTURAL CHARACTERIZATION, SUBSTRATE STEREOSELECTIVITY, AND PROCHIRAL SELECTIVITY OF THE WILD-TYPE AND I359L MUTANT FORMS
Authors: HAINING RL HUNTER AP VERONESE ME TRAGER WF RETTIE AE
Citation: Rl. Haining et al., ALLELIC VARIANTS OF HUMAN CYTOCHROME-P450 2C9 - BACULOVIRUS-MEDIATED EXPRESSION, PURIFICATION, STRUCTURAL CHARACTERIZATION, SUBSTRATE STEREOSELECTIVITY, AND PROCHIRAL SELECTIVITY OF THE WILD-TYPE AND I359L MUTANT FORMS, Archives of biochemistry and biophysics, 333(2), 1996, pp. 447-458
ISOTOPE EFFECT STUDIES ON THE CYTOCHROME-P450 ENZYMES
Authors: KORZEKWA KR GILLETTE JR TRAGER WF
Citation: Kr. Korzekwa et al., ISOTOPE EFFECT STUDIES ON THE CYTOCHROME-P450 ENZYMES, Drug metabolism reviews, 27(1-2), 1995, pp. 45-59
STEREOSELECTIVITY AND ISOTOPE EFFECTS ASSOCIATED WITH CYTOCHROME P450-CATALYZED OXIDATION OF (S)-NICOTINE - THE POSSIBILITY OF INITIAL HYDROGEN ATOM ABSTRACTION IN THE FORMATION OF THE DELTA-1',5'-NICOTINIUM ION
Authors: CARLSON TJ JONES JP PETERSON L CASTAGNOLI N IYER KR TRAGER WF
Citation: Tj. Carlson et al., STEREOSELECTIVITY AND ISOTOPE EFFECTS ASSOCIATED WITH CYTOCHROME P450-CATALYZED OXIDATION OF (S)-NICOTINE - THE POSSIBILITY OF INITIAL HYDROGEN ATOM ABSTRACTION IN THE FORMATION OF THE DELTA-1',5'-NICOTINIUM ION, Drug metabolism and disposition, 23(7), 1995, pp. 749-756
INHIBITION OF (S)-WARFARIN METABOLISM BY SULFINPYRAZONE AND ITS METABOLITES
Authors: HE MX KUNZE KL TRAGER WF
Citation: Mx. He et al., INHIBITION OF (S)-WARFARIN METABOLISM BY SULFINPYRAZONE AND ITS METABOLITES, Drug metabolism and disposition, 23(6), 1995, pp. 659-663
CATALYTIC ROLE OF CYTOCHROME P4503A4 IN MULTIPLE PATHWAYS OF ALFENTANIL METABOLISM
Authors: LABROO RB THUMMEL KE KUNZE KL PODOLL T TRAGER WF KHARASCH ED
Citation: Rb. Labroo et al., CATALYTIC ROLE OF CYTOCHROME P4503A4 IN MULTIPLE PATHWAYS OF ALFENTANIL METABOLISM, Drug metabolism and disposition, 23(4), 1995, pp. 490-496
Risultati: 1-25 | 26-38