Citation: Ipm. Tomlinson et M. Ilyas, Molecular pathology of solid tumours: some practical suggestions for translating research into clinical practice, J CL PATH-M, 54(4), 2001, pp. 203-205
Authors:
Woodford-Richens, KL
Rowan, AJ
Gorman, P
Halford, S
Bicknell, DC
Wasan, HS
Roylance, RR
Bodmer, WF
Tomlinson, IPM
Citation: Kl. Woodford-richens et al., SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway, P NAS US, 98(17), 2001, pp. 9719-9723
Authors:
Crabtree, MD
Tomlinson, IPM
Talbot, IC
Phillips, RKS
Citation: Md. Crabtree et al., Variability in the severity of colonic disease in familial adenomatous polyposis results from differences in tumour initiation rather than progression and depends relatively little on patient age, GUT, 49(4), 2001, pp. 540-543
Authors:
Woodford-Richens, KL
Halford, S
Rowan, A
Bevan, S
Aaltonen, LA
Hasan, H
Bicknell, D
Bodmer, WF
Houlston, RS
Tomlinson, IPM
Citation: Kl. Woodford-richens et al., CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers, BR J CANC, 84(10), 2001, pp. 1314-1316
Authors:
Woodford-Richens, KL
Rowan, AJ
Poulsom, R
Bevan, S
Salovaara, R
Aaltonen, LA
Houlston, RS
Wright, NA
Tomlinson, IPM
Citation: Kl. Woodford-richens et al., Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis - Evidence for a distinct genetic pathway and polyp morphologyin SMAD4 mutation carriers, AM J PATH, 159(4), 2001, pp. 1293-1300
Authors:
Zhou, XP
Woodford-Richens, K
Lehtonen, R
Kurose, K
Aldred, M
Hampel, H
Launonen, V
Virta, S
Pilarski, R
Salovaara, R
Bodmer, WF
Conrad, BA
Dunlop, M
Hodgson, SV
Iwama, T
Jarvinen, H
Kellokumpu, I
Kim, JC
Leggett, B
Markie, D
Mecklin, JP
Neale, K
Phillips, R
Piris, J
Rozen, P
Houlston, RS
Aaltonen, LA
Tomlinson, IPM
Eng, C
Citation: Xp. Zhou et al., Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes, AM J HU GEN, 69(4), 2001, pp. 704-711
Authors:
Alam, NA
Bevan, S
Churchman, M
Barclay, E
Barker, K
Jaeger, EEM
Nelson, HM
Healy, E
Pembroke, AC
Friedmann, PS
Dalziel, K
Calonje, E
Anderson, J
August, PJ
Davies, MG
Felix, R
Munro, CS
Murdoch, M
Rendall, J
Kennedy, S
Leigh, IM
Kelsell, DP
Tomlinson, IPM
Houlston, RS
Citation: Na. Alam et al., Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43, AM J HU GEN, 68(5), 2001, pp. 1264-1269
Authors:
Given, HF
Radbourne, R
Oag, H
Merritt, S
Barclay, E
Hanby, AM
Lamlum, H
McGrath, J
Curran, C
Tomlinson, IPM
Citation: Hf. Given et al., The androgen receptor exon 1 trinucleotide repeat does not act as a modifier of the age of presentation in breast cancer, EUR J CANC, 36(4), 2000, pp. 533-534
Authors:
Rowan, AJ
Lamlum, H
Ilyas, M
Wheeler, J
Straub, J
Papadopoulou, A
Bicknell, D
Bodmer, WF
Tomlinson, IPM
Citation: Aj. Rowan et al., APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits", P NAS US, 97(7), 2000, pp. 3352-3357
Authors:
Woodford-Richens, K
Bevan, S
Churchman, M
Dowling, B
Jones, D
Norbury, CG
Hodgson, SV
Desai, D
Neale, K
Phillips, RKS
Young, J
Leggett, B
Dunlop, M
Rozen, P
Eng, C
Markie, D
Rodriguez-Bigas, MA
Sheridan, E
Iwama, T
Eccles, D
Smith, GT
Kim, JC
Kim, KM
Sampson, JR
Evans, G
Tejpar, S
Bodmer, WF
Tomlinson, IPM
Houlston, RS
Citation: K. Woodford-richens et al., Analysis of genetic and phenotypic heterogeneity in juvenile polyposis, GUT, 46(5), 2000, pp. 656-660
Authors:
Hawkins, NJ
Gorman, P
Tomlinson, IPM
Bullpitt, P
Ward, RL
Citation: Nj. Hawkins et al., Colorectal carcinomas arising in the hyperplastic polyposis syndrome progress through the chromosomal instability pathway, AM J PATH, 157(2), 2000, pp. 385-392
Authors:
Sawyer, EJ
Hanby, AM
Ellis, P
Lakhani, SR
Ellis, LO
Boyle, S
Tomlinson, IPM
Citation: Ej. Sawyer et al., Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components, AM J PATH, 156(3), 2000, pp. 1093-1098
Authors:
Ylikorkala, A
Avizienyte, E
Tomlinson, IPM
Tiainen, M
Roth, S
Loukola, A
Hemminki, A
Johansson, M
Sistonen, P
Markie, D
Neale, K
Phillips, R
Zauber, P
Twama, T
Sampson, J
Jarvinen, H
Makela, TP
Aaltonen, LA
Citation: A. Ylikorkala et al., Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer, HUM MOL GEN, 8(1), 1999, pp. 45-51
Authors:
Ilyas, M
Straub, J
Tomlinson, IPM
Bodmer, WF
Citation: M. Ilyas et al., Genetic pathways in colorectal and other cancers (Reprinted from Eur J Cancer, vol 35, pg 335-351, 1999), EUR J CANC, 35(14), 1999, pp. 1986-2002
Authors:
Wheeler, JMD
Beck, NE
Kim, HC
Tomlinson, IPM
Mortensen, NJM
Bodmer, WF
Citation: Jmd. Wheeler et al., Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: The predominant role of hMLH1, P NAS US, 96(18), 1999, pp. 10296-10301
Authors:
Wang, ZJ
Churchman, M
Campbell, IG
Xu, WH
Yan, ZY
McCluggage, WG
Foulkes, WD
Tomlinson, IPM
Citation: Zj. Wang et al., Allele loss and mutation screen at the Peutz-Jeghers (LKB1) locus (19p13.3) in sporadic ovarian tumours, BR J CANC, 80(1-2), 1999, pp. 70-72