Authors:
Hirst, CE
Buzza, MS
Sutton, VR
Trapani, JA
Loveland, KL
Bird, PI
Citation: Ce. Hirst et al., Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction, MOL HUM REP, 7(12), 2001, pp. 1133-1142
Authors:
Ruefli, AA
Davis, JE
Sutton, VR
Trapani, JA
Smyth, MJ
Johnstone, RW
Citation: Aa. Ruefli et al., Dissecting the apoptotic mechanisms of chemotherapeutic drugs and lymphocytes to design effective anticancer therapies, DRUG DEV R, 52(4), 2001, pp. 549-557
Authors:
Briggs, LJ
Johnstone, RW
Elliot, RM
Xiao, CY
Dawson, M
Trapani, JA
Jans, DA
Citation: Lj. Briggs et al., Novel properties of the protein kinase CK2-site-regulated nuclear-localization sequence of the interferon-induced nuclear factor IFI 16, BIOCHEM J, 353, 2001, pp. 69-77
Authors:
Haynes, NM
Snook, MB
Trapani, JA
Cerruti, L
Jane, SM
Smyth, MJ
Darcy, PK
Citation: Nm. Haynes et al., Redirecting mouse CTL against colon carcinoma: Superior signaling efficacyof single-chain variable domain chimeras containing TCR-zeta vs Fc epsilonRI-gamma, J IMMUNOL, 166(1), 2001, pp. 182-187
Citation: Je. Davis et al., Granzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity, EUR J IMMUN, 31(1), 2001, pp. 39-47
Authors:
Davis, JE
Sutton, VR
Smyth, MJ
Trapani, JA
Citation: Je. Davis et al., Dependence of granzyme B-mediated cell death on a pathway regulated by Bcl-2 or its viral homolog, BHRF1, CELL DEAT D, 7(10), 2000, pp. 973-983
Authors:
Chen, Q
Jackson, H
Cebon, J
Gibbs, P
Davis, ID
Trapani, JA
Citation: Q. Chen et al., A direct comparison of cytolytic T-lymphocyte responses to Melan-A peptides in vitro: differential immunogenicity of Melan-A(27-35) and Melan-A(26-35) (vol 10, pg 21, 2000), MELANOMA RE, 10(2), 2000, pp. 193-193
Authors:
Chen, Q
Jackson, H
Cebon, J
Gibbs, P
Davis, ID
Trapani, JA
Citation: Q. Chen et al., A direct comparison of cytolytic T-lymphocyte responses to Melan-A peptides in vitro: differential immunogenicity of Melan-A(27-35) and Melan-A(26-35), MELANOMA RE, 10(1), 2000, pp. 16-25
Authors:
Trapani, JA
Davis, J
Sutton, VR
Smyth, MJ
Citation: Ja. Trapani et al., Proapoptotic functions of cytotoxic lymphocyte granule constituents in vitro and in vivo, CURR OP IM, 12(3), 2000, pp. 323-329
Authors:
Johnstone, RW
Wei, W
Greenway, A
Trapani, JA
Citation: Rw. Johnstone et al., Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16, ONCOGENE, 19(52), 2000, pp. 6033-6042
Authors:
Wei, S
Gilvary, DL
Corliss, BC
Sebti, S
Sun, JZ
Straus, DB
Leibson, PJ
Trapani, JA
Hamilton, AD
Weber, MJ
Djeu, JY
Citation: S. Wei et al., Direct tumor lysis by NK cells uses a Ras-independent mitogen-activated protein kinase signal pathway, J IMMUNOL, 165(7), 2000, pp. 3811-3819
Authors:
Darcy, PK
Haynes, NM
Snook, MB
Trapani, JA
Cerruti, L
Jane, SM
Smyth, MJ
Citation: Pk. Darcy et al., Redirected perforin-dependent lysis of colon carcinoma by ex vivo genetically engineered CTL, J IMMUNOL, 164(7), 2000, pp. 3705-3712
Authors:
Sutton, VR
Davis, JE
Cancilla, M
Johnstone, RW
Ruefli, AA
Sedelies, K
Browne, KA
Trapani, JA
Citation: Vr. Sutton et al., Initiation of apoptosis by granzyme B requires direct cleavage of Bid, butnot direct granzyme B-mediated caspase activation, J EXP MED, 192(10), 2000, pp. 1403-1413
Authors:
Browne, KA
Johnstone, RW
Jans, DA
Trapani, JA
Citation: Ka. Browne et al., Filamin (280-kDa actin-binding protein) is a caspase substrate and is alsocleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis, J BIOL CHEM, 275(50), 2000, pp. 39262-39266
Citation: Ej. Blink et al., Perforin-dependent nuclear targeting of granzymes: A central role in the nuclear events of granule-exocytosis-mediated apoptosis?, IMM CELL B, 77(3), 1999, pp. 206-215
Authors:
Edwards, KM
Davis, JE
Browne, KA
Sutton, VR
Trapani, JA
Citation: Km. Edwards et al., Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction. (vol 77, pg 76, 1999), IMM CELL B, 77(3), 1999, pp. 287-287
Authors:
Edwards, KM
Davis, JE
Browne, KA
Sutton, VR
Trapani, JA
Citation: Km. Edwards et al., Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction, IMM CELL B, 77(1), 1999, pp. 76-89
Citation: Nm. Haynes et al., Fas-ligand-mediated lysis of erbB-2-expressing tumour cells by redirected cytotoxic T lymphocytes, CANCER IMMU, 47(5), 1999, pp. 278-286
Citation: Rw. Johnstone et Ja. Trapani, Transcription and growth regulatory functions of the HIN-200 family of proteins, MOL CELL B, 19(9), 1999, pp. 5833-5838
Authors:
Browne, KA
Blink, E
Sutton, VR
Froelich, CJ
Jans, DA
Trapani, JA
Citation: Ka. Browne et al., Cytosolic delivery of granzyme B by bacterial toxins: Evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin, MOL CELL B, 19(12), 1999, pp. 8604-8615