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Results: 1-24 |
Results: 24
GR89,696: A potent kappa-opioid agonist with subtype selectivity in rhesusmonkeys
Authors: Butelman, ER Ko, MCH Traynor, JR Vivian, JA Kreek, MJ Woods, JH
Citation: Er. Butelman et al., GR89,696: A potent kappa-opioid agonist with subtype selectivity in rhesusmonkeys, J PHARM EXP, 298(3), 2001, pp. 1049-1059
Stimulation of guanosine-5 '-O-(3-[S-35]thio)triphosphate binding in digitonin-permeabilized C6 rat glioma cells: Evidence for an organized association of mu-opioid receptors and G protein
Authors: Alt, A McFadyen, IJ Fan, CD Woods, JH Traynor, JR
Citation: A. Alt et al., Stimulation of guanosine-5 '-O-(3-[S-35]thio)triphosphate binding in digitonin-permeabilized C6 rat glioma cells: Evidence for an organized association of mu-opioid receptors and G protein, J PHARM EXP, 298(1), 2001, pp. 116-121
Modifications of the cyclic mu receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]NH2 (Et): effects on opioid receptor binding and activation
Authors: McFadyen, IJ Ho, JC Mosberg, HI Traynor, JR
Citation: Ij. Mcfadyen et al., Modifications of the cyclic mu receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]NH2 (Et): effects on opioid receptor binding and activation, J PEPT RES, 55(3), 2000, pp. 255-261
Enantiomeric (-)-(1R,5R,9R) and (+)-(1S,5S,9S) heterocyclic N-substituted-normetazocines: Synthesis of potent and selective antinociceptives and opioid antagonists through N-substituent modification
Authors: May, EL Aceto, MD Bowman, ER Traynor, JR Woods, JH Jacobson, AE Harris, LS
Citation: El. May et al., Enantiomeric (-)-(1R,5R,9R) and (+)-(1S,5S,9S) heterocyclic N-substituted-normetazocines: Synthesis of potent and selective antinociceptives and opioid antagonists through N-substituent modification, MED CHEM RE, 10(3), 2000, pp. 178-185
N-cyclohexylethyl-N-noroxymorphindole: A mu-opioid preferring analogue of naltrindole
Authors: Coop, A Jacobson, AE Aceto, MD Harris, LS Traynor, JR Woods, JH Rice, KC
Citation: A. Coop et al., N-cyclohexylethyl-N-noroxymorphindole: A mu-opioid preferring analogue of naltrindole, BIOORG MED, 10(21), 2000, pp. 2449-2451
Characterization of ZFOR1, a putative delta-opioid receptor from the teleost zebrafish (Danio rerio)
Authors: Rodriguez, RE Barrallo, A Garcia-Malvar, F McFadyen, IJ Gonzalez-Sarmiento, R Traynor, JR
Citation: Re. Rodriguez et al., Characterization of ZFOR1, a putative delta-opioid receptor from the teleost zebrafish (Danio rerio), NEUROSCI L, 288(3), 2000, pp. 207-210
The steroid 17 alpha-acetoxy-6-dimethylaminomethyl-21-fluoro-3-ethoxy-pregna-3,5-dien-20-one (SC17599) is a selective mu-opioid agonist: Implicationsfor the mu-opioid pharmacophore
Authors: McFadyen, IJ Houshyar, H Liu-Chen, LY Woods, JH Traynor, JR
Citation: Ij. Mcfadyen et al., The steroid 17 alpha-acetoxy-6-dimethylaminomethyl-21-fluoro-3-ethoxy-pregna-3,5-dien-20-one (SC17599) is a selective mu-opioid agonist: Implicationsfor the mu-opioid pharmacophore, MOLEC PHARM, 58(4), 2000, pp. 669-676
Tetrapeptide derivatives of [D-Pen(2), D-Pen(5)]-enkephalin (DPDPE) lacking an N-terminal tyrosine residue are agonists at the mu-opioid receptor
Authors: Mcfadyen, IJ Sobczyk-Kojiro, K Schaefer, MJ Ho, JC Omnaas, JR Mosberg, HI Traynor, JR
Citation: Ij. Mcfadyen et al., Tetrapeptide derivatives of [D-Pen(2), D-Pen(5)]-enkephalin (DPDPE) lacking an N-terminal tyrosine residue are agonists at the mu-opioid receptor, J PHARM EXP, 295(3), 2000, pp. 960-966
Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: Comparison with clocinnamox, beta-funaltrexamine, and beta-chlornaltrexamine
Authors: Broadbear, JH Sumpter, TL Burke, TF Husbands, SM Lewis, JW Woods, JH Traynor, JR
Citation: Jh. Broadbear et al., Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: Comparison with clocinnamox, beta-funaltrexamine, and beta-chlornaltrexamine, J PHARM EXP, 294(3), 2000, pp. 933-940
BU48: A novel buprenorphine analog that exhibits delta-opioid-mediated convulsions but not delta-opioid-mediated antinociception in mice
Authors: Broom, DC Guo, L Coop, A Husbands, SM Lewis, JW Woods, JH Traynor, JR
Citation: Dc. Broom et al., BU48: A novel buprenorphine analog that exhibits delta-opioid-mediated convulsions but not delta-opioid-mediated antinociception in mice, J PHARM EXP, 294(3), 2000, pp. 1195-1200
An immortalized myocyte cell line, HL-1, expresses a functional delta-opioid receptor
Authors: Neilan, CL Kenyon, E Kovach, MA Bowden, K Claycomb, WC Traynor, JR Bolling, SF
Citation: Cl. Neilan et al., An immortalized myocyte cell line, HL-1, expresses a functional delta-opioid receptor, J MOL CEL C, 32(12), 2000, pp. 2187-2193
Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5,9-dimethyl-2 '-hydroxy-6,7-benzomorphan homologues
Authors: May, EL Jacobson, AE Mattson, MV Traynor, JR Woods, JH Harris, LS Bowman, ER Aceto, MD
Citation: El. May et al., Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5,9-dimethyl-2 '-hydroxy-6,7-benzomorphan homologues, J MED CHEM, 43(26), 2000, pp. 5030-5036
3-deoxyclocinnamox: The first high-affinity, nonpeptide mu-opioid antagonist lacking a phenolic hydroxyl group
Authors: Derrick, I Neilan, CL Andes, J Husbands, SM Woods, JH Traynor, JR Lewis, JW
Citation: I. Derrick et al., 3-deoxyclocinnamox: The first high-affinity, nonpeptide mu-opioid antagonist lacking a phenolic hydroxyl group, J MED CHEM, 43(17), 2000, pp. 3348-3350
Structural determinants of opioid activity in the orvinols and related structures. Ethers of 7,8-cyclopenta-fused analogs of buprenorphine
Authors: Coop, A Berzetei-Gurske, I Burnside, J Toll, L Traynor, JR Husbands, SM Lewis, JW
Citation: A. Coop et al., Structural determinants of opioid activity in the orvinols and related structures. Ethers of 7,8-cyclopenta-fused analogs of buprenorphine, HELV CHIM A, 83(4), 2000, pp. 687-693
Cinnamoyl derivatives of 7 alpha-amino- and 7 alpha-(aminomethyl)-N-(cyclopropylmethyl)-6,14-endo-ethanotetrahydronororipavines are high-potency opioid antagonists
Authors: Derrick, I Husbands, SM Broadbear, J Traynor, JR Woods, JH Lewis, JW
Citation: I. Derrick et al., Cinnamoyl derivatives of 7 alpha-amino- and 7 alpha-(aminomethyl)-N-(cyclopropylmethyl)-6,14-endo-ethanotetrahydronororipavines are high-potency opioid antagonists, HELV CHIM A, 83(12), 2000, pp. 3122-3130
Activation of G protein by opioid receptors: role of receptor number and G-protein concentration
Authors: Remmers, AE Clark, MJ Alt, A Medzihradsky, F Woods, JH Traynor, JR
Citation: Ae. Remmers et al., Activation of G protein by opioid receptors: role of receptor number and G-protein concentration, EUR J PHARM, 396(2-3), 2000, pp. 67-75
Antinociceptive and other behavioral effects of the steroid SC17599 are mediated by the mu-opioid receptor
Authors: Houshyar, H Mc Fadyen, IJ Woods, JH Traynor, JR
Citation: H. Houshyar et al., Antinociceptive and other behavioral effects of the steroid SC17599 are mediated by the mu-opioid receptor, EUR J PHARM, 395(2), 2000, pp. 121-128
Ring-constrained orvinols as analogs of buprenorphine: Differences in opioid activity related to configuration of C-20 hydroxyl group
Authors: Traynor, JR Guo, L Coop, A Lewis, JW Woods, JH
Citation: Jr. Traynor et al., Ring-constrained orvinols as analogs of buprenorphine: Differences in opioid activity related to configuration of C-20 hydroxyl group, J PHARM EXP, 291(3), 1999, pp. 1093-1099
kappa-opioid receptor effects of butorphanol in rhesus monkeys
Authors: Vivian, JA Deyoung, MB Sumpter, TL Traynor, JR Lewis, JW Woods, JH
Citation: Ja. Vivian et al., kappa-opioid receptor effects of butorphanol in rhesus monkeys, J PHARM EXP, 290(1), 1999, pp. 259-265
mu-Opioid receptor specific antagonist cyprodime: characterization by in vitro radioligand and [S-35]GTP gamma S binding assays
Authors: Marki, A Monory, K Otvos, F Toth, G Krassnig, R Schmidhammer, H Traynor, JR Roques, BP Maldonado, R Borsodi, A
Citation: A. Marki et al., mu-Opioid receptor specific antagonist cyprodime: characterization by in vitro radioligand and [S-35]GTP gamma S binding assays, EUR J PHARM, 383(2), 1999, pp. 209-214
Differential binding properties of oripavines at cloned mu- and delta-opioid receptors
Authors: Lee, KO Akil, H Woods, JH Traynor, JR
Citation: Ko. Lee et al., Differential binding properties of oripavines at cloned mu- and delta-opioid receptors, EUR J PHARM, 378(3), 1999, pp. 323-330
Constitutive activity of the delta-opioid receptor expressed in C6 glioma cells: identification of non-peptide delta-inverse agonists
Authors: Neilan, CL Akil, H Woods, JH Traynor, JR
Citation: Cl. Neilan et al., Constitutive activity of the delta-opioid receptor expressed in C6 glioma cells: identification of non-peptide delta-inverse agonists, BR J PHARM, 128(3), 1999, pp. 556-562
The effects of the phyllolitorin analogue [desTrp(3),Leu(8)]phyllolitorin on scratching induced by bombesin and related peptides in rats
Authors: Johnson, MD Ko, MC Choo, KS Traynor, JR Mosberg, HI Naughton, NN Woods, JH
Citation: Md. Johnson et al., The effects of the phyllolitorin analogue [desTrp(3),Leu(8)]phyllolitorin on scratching induced by bombesin and related peptides in rats, BRAIN RES, 839(1), 1999, pp. 194-198
Synthesis and biological evaluation of 14-alkoxymorphinans. 16. 14-O-alkylderivatives of the mu opioid receptor antagonist cyprodime
Authors: Schmidhammer, H Krassnig, R Greiner, E Traynor, JR
Citation: H. Schmidhammer et al., Synthesis and biological evaluation of 14-alkoxymorphinans. 16. 14-O-alkylderivatives of the mu opioid receptor antagonist cyprodime, HETEROCYCLE, 49, 1998, pp. 489-497
Risultati: 1-24 |