Citation: K. Ogata et H. Umeyama, THE ROLE PLAYED BY ENVIRONMENTAL RESIDUES ON SIDE-CHAIN TORSIONAL ANGLES WITHIN HOMOLOGOUS FAMILIES OF PROTEINS - A NEW METHOD OF SIDE-CHAIN MODELING, Proteins, 31(4), 1998, pp. 355-369
Authors:
MIYATA T
FISCHER F
UMEYAMA H
APPERT A
JAMBOU D
KATO H
Citation: T. Miyata et al., FACTOR-X NICE-I AND NICE-II - 2 NOVEL MISSENSE MUTATIONS (MET-40VAL AND PRO304SER) IN PATIENT WITH COAGULATION-FACTOR-X DEFICIENCY, Thrombosis and haemostasis, 80(4), 1998, pp. 709-710
Authors:
MIYATA T
KOJIMA T
SUZUKI K
UMEYAMA H
YAMAZAKI T
KAMIYA T
TOYODA H
KATO H
Citation: T. Miyata et al., FACTOR-X NAGOYA-1 AND NAGOYA-2 - A CRM- FACTOR-X DEFICIENCY AND A DYSFUNCTIONAL CRM-X DEFICIENCY CHARACTERIZED BY SUBSTITUTION OF ARG306 BYCYS AND OF GLY366 BY SER, RESPECTIVELY( FACTOR), Thrombosis and haemostasis, 79(3), 1998, pp. 486-490
Citation: M. Takedashitaka et H. Umeyama, ELUCIDATION OF THE CAUSE FOR REDUCED ACTIVITY OF ABNORMAL HUMAN PLASMIN CONTAINING AN ALA(55)-THR MUTATION - IMPORTANCE OF HIGHLY CONSERVEDALA(55) IN SERINE PROTEASES, FEBS letters, 425(3), 1998, pp. 448-452
Citation: M. Takedashitaka et H. Umeyama, EFFECT OF EXCEPTIONAL VALINE REPLACEMENT FOR HIGHLY CONSERVED ALANINE-55 ON THE CATALYTIC SITE STRUCTURE OF CHYMOTRYPSIN-LIKE SERINE-PROTEASE, Chemical and Pharmaceutical Bulletin, 46(9), 1998, pp. 1343-1348
Authors:
SUMIKAWA H
SUZUKI E
FUKUHARA K
NAKAJIMA Y
KAMIYA K
UMEYAMA H
Citation: H. Sumikawa et al., DYNAMIC STRUCTURES OF GRANULOCYTE-COLONY-STIMULATING FACTOR PROTEINS STUDIED BY NORMAL-MODE ANALYSIS - 2 DOMAIN-TYPE MOTIONS IN LOW-FREQUENCY MODES, Chemical and Pharmaceutical Bulletin, 46(7), 1998, pp. 1069-1077
Authors:
TAKAHASHI N
TSUKAMOTO H
UMEYAMA H
CASTAMAN G
RODEGHIERO F
ICHINOSE A
Citation: N. Takahashi et al., MOLECULAR MECHANISMS OF TYPE-II FACTOR-XIII DEFICIENCY - NOVEL GLY562-ARG MUTATION AND C-TERMINAL TRUNCATION OF THE A SUBUNIT CAUSE FACTOR-XIII DEFICIENCY AS CHARACTERIZED IN A MAMMALIAN EXPRESSION SYSTEM, Blood, 91(8), 1998, pp. 2830-2838
Authors:
ICHINOSE A
IZUMI T
SAITO T
YAMAZAKI T
TSUKAMOTO H
UMEYAMA H
TAKAMATSU J
SAITO H
Citation: A. Ichinose et al., NOVEL MUTATIONS CAUSE EXON-III SKIPPING AND CONFORMATIONAL CHANGE OF THE A SUBUNIT WHICH IS PREDICTED BY MOLECULAR MODELING, Thrombosis and haemostasis, 1997, pp. 3093-3093
Citation: T. Yoneda et al., A COMPUTER MODELING STUDY OF THE INTERACTION BETWEEN TISSUE FACTOR PATHWAY INHIBITOR AND BLOOD-COAGULATION FACTOR XA, Journal of protein chemistry, 16(6), 1997, pp. 597-605
Citation: K. Ogata et H. Umeyama, PREDICTION OF PROTEIN SIDE-CHAIN CONFORMATIONS BY PRINCIPAL COMPONENTANALYSIS FOR FIXED MAIN-CHAIN ATOMS, Protein engineering, 10(4), 1997, pp. 353-359
Citation: J. Higo et H. Umeyama, A THEORETICAL APPROACH TO THE BELL-SHAPED DEPENDENCY OF CELL-PROLIFERATION ON THE HORMONE CONCENTRATION, Journal of theoretical biology, 186(4), 1997, pp. 477-490
Authors:
ISHII I
IZUMI T
TSUKAMOTO H
UMEYAMA H
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SHIMIZU T
Citation: I. Ishii et al., ALANINE EXCHANGES OF POLAR AMINO-ACIDS IN THE TRANSMEMBRANE DOMAINS OF A PLATELET-ACTIVATING-FACTOR RECEPTOR GENERATE BOTH CONSTITUTIVELY ACTIVE AND INACTIVE MUTANTS, The Journal of biological chemistry, 272(12), 1997, pp. 7846-7854
Authors:
TAKAHASHI N
TSUKAMOTO H
UMEYAMA H
CASTAMAN G
RODEGHIERO F
YAMAZAKI T
ICHINOSE A
Citation: N. Takahashi et al., MOLECULAR MECHANISMS OF TYPE-II FACTOR-XIII DEFICIENCY - NOVEL GLY562-ARG MUTATION AND C-TERMINAL TRUNCATION OF THE A SUBUNIT CAUSE FACTOR-XIII DEFICIENCY AS CHARACTERIZED IN A MAMMALIAN EXPRESSION SYSTEM, Blood, 90(10), 1997, pp. 2062-2062
Authors:
MIYATA T
SAKATA T
ZHENG YZ
TSUKAMOTO H
UMEYAMA H
UCHIYAMA S
IKUSAKA M
YOSHIOKA A
IMANAKA Y
FUJIMURA H
KAMBAYASHI J
KATO H
Citation: T. Miyata et al., GENETIC-CHARACTERIZATION OF PROTEIN-C DEFICIENCY IN JAPANESE SUBJECTSUSING A RAPID AND NONRADIOACTIVE METHOD FOR SINGLE-STRAND CONFORMATIONAL POLYMORPHISM ANALYSIS AND A MODEL-BUILDING, Thrombosis and haemostasis, 76(3), 1996, pp. 302-311
Citation: S. Yoneda et al., MOLECULAR-DYNAMICS SIMULATION OF A RHINOVIRUS CAPSID UNDER ROTATIONALSYMMETRY BOUNDARY-CONDITIONS, Journal of computational chemistry, 17(2), 1996, pp. 191-203
Citation: H. Umeyama et H. Tsukamoto, PROTEIN-C MODELING AND THE HEREDITARY-DISEASES, Progress in Biophysics and Molecular Biology, 65, 1996, pp. 211-211
Authors:
MURAKAMI Y
KOSHI M
MATSUI H
KAMIYA K
UMEYAMA H
Citation: Y. Murakami et al., KINETICS OF THE SIH3-2 REACTION - A NEW TRANSITION-STATE FOR SIO PRODUCTION(O), Journal of physical chemistry, 100(44), 1996, pp. 17501-17506
Authors:
KURIKI T
KANEKO H
YANASE M
TAKATA H
SHIMADA J
HANDA S
TAKADA T
UMEYAMA H
OKADA S
Citation: T. Kuriki et al., CONTROLLING SUBSTRATE PREFERENCE AND TRANSGLYCOSYLATION ACTIVITY OF NEOPULLULANASE BY MANIPULATING STERIC CONSTRAINT AND HYDROPHOBICITY IN ACTIVE-CENTER, The Journal of biological chemistry, 271(29), 1996, pp. 17321-17329
Authors:
MATSUEDA R
UMEYAMA H
PURI RN
BRADFORD HN
COLMAN RW
Citation: R. Matsueda et al., DESIGN AND SYNTHESIS OF A KININOGEN-BASED SELECTIVE INHIBITOR OF THROMBIN-INDUCED PLATELET-AGGREGATION, Peptide research, 7(1), 1994, pp. 32-35
Authors:
ZHENG YZ
SAKATA T
MATSUSUE T
UMEYAMA H
KATO H
MIYATA T
Citation: Yz. Zheng et al., 6 MISSENSE MUTATIONS ASSOCIATED WITH TYPE-I AND TYPE-II PROTEIN-C DEFICIENCY AND IMPLICATIONS OBTAINED FROM MOLECULAR MODELING, Blood coagulation & fibrinolysis, 5(5), 1994, pp. 687-696