Citation: K. Ulbrich et J. Kahovec, Polymers in medicine - Invited lectures presented at the 40(th) Microsymposium of the Prague Meetings on Macromolecules held in Prague, Czech republic - July 17-20, 2000 - Preface, MACRO SYMP, 172, 2001, pp. NIL_6-NIL_7
Authors:
Dautzenberg, H
Zintchenko, A
Konak, C
Reschel, T
Subr, V
Ulbrich, K
Citation: H. Dautzenberg et al., Polycationic graft copolymers as carriers for oligonucleotide delivery. Complexes of oligonucleotides with polycationic graft copolymers, LANGMUIR, 17(10), 2001, pp. 3096-3102
Authors:
Rihova, B
Etrych, T
Pechar, M
Jelinkova, M
Stastny, M
Hovorka, O
Kovar, M
Ulbrich, K
Citation: B. Rihova et al., Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes, J CONTR REL, 74(1-3), 2001, pp. 225-232
Authors:
Etrych, T
Jelinkova, M
Rihova, B
Ulbrich, K
Citation: T. Etrych et al., New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage:synthesis and preliminary in vitro and in vivo biological properties, J CONTR REL, 73(1), 2001, pp. 89-102
Authors:
Soucek, J
Pouckova, P
Zadinova, M
Hlouskova, D
Plocova, D
Strohalm, J
Hrkal, Z
Olear, T
Ulbrich, K
Citation: J. Soucek et al., Polymer conjugated bovine seminal ribonuclease inhibits growth of solid tumors and development of metastases in mice, NEOPLASMA, 48(2), 2001, pp. 127-132
Authors:
Prokopova-Kubinova, S
Vargova, L
Tao, L
Ulbrich, K
Subr, V
Sykova, E
Nicholson, C
Citation: S. Prokopova-kubinova et al., Poly[N-(2-hydroxypropyl)methacrylamide] polymers diffuse in brain extracellular space with same tortuosity as small molecules, BIOPHYS J, 80(1), 2001, pp. 542-548
Authors:
Rihova, B
Jelinkova, M
Strohalm, J
St'astny, M
Hovorka, O
Plocova, D
Kovar, M
Draberova, L
Ulbrich, K
Citation: B. Rihova et al., Antiproliferative effect of a lectin- and anti-Thy-1.2 antibody-targeted HPMA copolymer-bound doxorubicin on primary and metastatic human colorectal carcinoma and on human colorectal carcinoma transfected with the mouse Thy-1.2 gene, BIOCONJ CHE, 11(5), 2000, pp. 664-673
Authors:
Oupicky, D
Howard, KA
Konak, C
Dash, PR
Ulbrich, K
Seymour, LW
Citation: D. Oupicky et al., Steric stabilization of poly-L-lysine/DNA complexes by the covalent attachment of semitelechelic poly [N-(2-hydroxypropyl)methacrylamide], BIOCONJ CHE, 11(4), 2000, pp. 492-501
Authors:
Pechar, M
Ulbrich, K
Subr, V
Seymour, LW
Schacht, EH
Citation: M. Pechar et al., Poly(ethylene glycol) multiblock copolymer as a carrier of anti-cancer drug doxorubicin, BIOCONJ CHE, 11(2), 2000, pp. 131-139
Authors:
Fisher, KD
Ulbrich, K
Subr, V
Ward, CM
Mautner, V
Blakey, D
Seymour, LW
Citation: Kd. Fisher et al., A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression, GENE THER, 7(15), 2000, pp. 1337-1343
Authors:
Read, ML
Dash, PR
Clark, A
Howard, KA
Oupicky, D
Toncheva, V
Alpar, HO
Schacht, EH
Ulbrich, K
Seymour, LW
Citation: Ml. Read et al., Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers, EUR J PH SC, 10(3), 2000, pp. 169-177
Authors:
Ulbrich, K
Strohalm, J
Plocova, D
Oupicky, D
Subr, V
Soucek, J
Pouckova, P
Matousek, J
Citation: K. Ulbrich et al., Poly[N-(2-hydroxypropyl)methacrylamide] conjugates of bovine seminal ribonuclease. Synthesis, physicochemical, and preliminary biological evaluation, J BIOACT C, 15(1), 2000, pp. 4-26
Authors:
Howard, KA
Dash, PR
Read, ML
Ward, K
Tomkins, LM
Nazarova, O
Ulbrich, K
Seymour, LW
Citation: Ka. Howard et al., Influence of hydrophilicity of cationic polymers on the biophysical properties of polyelectrolyte complexes formed by self-assembly with DNA, BBA-GEN SUB, 1475(3), 2000, pp. 245-255
Authors:
Oupicky, D
Konak, C
Ulbrich, K
Wolfert, MA
Seymour, LW
Citation: D. Oupicky et al., DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers, J CONTR REL, 65(1-2), 2000, pp. 149-171
Authors:
Ulbrich, K
Subr, V
Strohalm, J
Plocova, D
Jelinkova, M
Rihova, B
Citation: K. Ulbrich et al., Polymeric drugs based on conjugates of synthetic and natural macromolecules I. Synthesis and physico-chemical characterisation, J CONTR REL, 64(1-3), 2000, pp. 63-79
Authors:
Rihova, B
Jelinkova, M
Strohalm, J
Subr, V
Plocova, D
Hovorka, O
Novak, M
Plundrova, D
Germano, Y
Ulbrich, K
Citation: B. Rihova et al., Polymeric drugs based on conjugates of synthetic and natural macromolecules. II. Anti-cancer activity of antibody or (Fab ')(2)-targeted conjugates and combined therapy with immunomodulators, J CONTR REL, 64(1-3), 2000, pp. 241-261
Authors:
Konak, C
Oupicky, D
Chytry, V
Ulbrich, K
Helmstedt, M
Citation: C. Konak et al., Thermally controlled association in aqueous solutions of diblock copolymers of poly[N-(2-hydroxypropyl)methacrylamide] and poly(N-isopropylacrylamide), MACROMOLEC, 33(15), 2000, pp. 5318-5320
Authors:
Dash, PR
Read, ML
Fisher, KD
Howard, KA
Wolfert, M
Oupicky, D
Subr, V
Strohalm, J
Ulbrich, K
Seymour, LW
Citation: Pr. Dash et al., Decreased binding to proteins and cells of polymeric gene delivery vectorssurface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin, J BIOL CHEM, 275(6), 2000, pp. 3793-3802
Authors:
Wolfert, MA
Dash, PR
Nazarova, O
Oupicky, D
Seymour, LW
Smart, S
Strohalm, J
Ulbrich, K
Citation: Ma. Wolfert et al., Polyelectrolyte vectors for gene delivery: Influence of cationic polymer on biophysical properties of complexes formed with DNA, BIOCONJ CHE, 10(6), 1999, pp. 993-1004
Authors:
Oupicky, D
Konak, C
Dash, PR
Seymour, LW
Ulbrich, K
Citation: D. Oupicky et al., Effect of albumin and polyanion on the structure of DNA complexes with polycation containing hydrophilic nonionic block, BIOCONJ CHE, 10(5), 1999, pp. 764-772
Authors:
St'astny, M
Strohalm, J
Plocova, D
Ulbrich, K
Rihova, B
Citation: M. St'Astny et al., A possibility to overcome P-glycoprotein (PGP)-mediated multidrug resistance by antibody-targeted drugs conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier, EUR J CANC, 35(3), 1999, pp. 459-466