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Results: 1-25 | 26-50 | 51-69
Results: 1-25/69
TOXICOLOGICAL EVALUATION AND RISK ASSESSMENT OF CHEMICAL-MIXTURES
Authors: CASSEE FR GROTEN JP VANBLADEREN PJ FERON VJ
Citation: Fr. Cassee et al., TOXICOLOGICAL EVALUATION AND RISK ASSESSMENT OF CHEMICAL-MIXTURES, Critical reviews in toxicology, 28(1), 1998, pp. 73-101
CONVERSION OF PENTAHALOGENATED PHENOLS BY MICROPEROXIDASE-8 H2O2 TO BENZOQUINONE-TYPE PRODUCTS/
Authors: OSMAN AM POSTHUMUS MA VEEGER C VANBLADEREN PJ LAANE C RIETJENS IMCM
Citation: Am. Osman et al., CONVERSION OF PENTAHALOGENATED PHENOLS BY MICROPEROXIDASE-8 H2O2 TO BENZOQUINONE-TYPE PRODUCTS/, Chemical research in toxicology, 11(11), 1998, pp. 1319-1325
INCREASED BIOACTIVATION OF DIHALOALKANES IN RAT-LIVER DUE TO INDUCTION OF CLASS-THETA GLUTATHIONE-S-TRANSFERASE T1-1
Authors: SHERRATT PJ MANSON MM THOMSON AM HISSINK EAM NEAL GE VANBLADEREN PJ GREEN T HAYES JD
Citation: Pj. Sherratt et al., INCREASED BIOACTIVATION OF DIHALOALKANES IN RAT-LIVER DUE TO INDUCTION OF CLASS-THETA GLUTATHIONE-S-TRANSFERASE T1-1, Biochemical journal, 335, 1998, pp. 619-630
DISPOSITION OF 1,2-[C-14]DIBROMOETHANE IN MALE WISTAR RATS
Authors: WORMHOUDT LW HISSINK AM COMMANDEUR JNM VANBLADEREN PJ VERMEULEN NPE
Citation: Lw. Wormhoudt et al., DISPOSITION OF 1,2-[C-14]DIBROMOETHANE IN MALE WISTAR RATS, Drug metabolism and disposition, 26(5), 1998, pp. 437-447
GLUTATHIONE-DEPENDENT BIOTRANSFORMATION OF THE ALKYLATING DRUG THIOTEPA AND TRANSPORT OF ITS METABOLITE MONOGLUTATHIONYLTHIOTEPA IN HUMAN MCF-7 BREAST-CANCER CELLS
Authors: CNUBBEN NHP ROMMENS AJM OUDSHOORN MJ VANBLADEREN PJ
Citation: Nhp. Cnubben et al., GLUTATHIONE-DEPENDENT BIOTRANSFORMATION OF THE ALKYLATING DRUG THIOTEPA AND TRANSPORT OF ITS METABOLITE MONOGLUTATHIONYLTHIOTEPA IN HUMAN MCF-7 BREAST-CANCER CELLS, Cancer research, 58(20), 1998, pp. 4616-4623
CYTOCHROME P450-CATALYZED OXIDATION OF HALOBENZENE DERIVATIVES
Authors: RIETJENS IMCM DENBESTEN C HANZLIK RP VANBLADEREN PJ
Citation: Imcm. Rietjens et al., CYTOCHROME P450-CATALYZED OXIDATION OF HALOBENZENE DERIVATIVES, Chemical research in toxicology, 10(6), 1997, pp. 629-635
STEREOSELECTIVE CONJUGATION OF PROSTAGLANDIN A(2) AND PROSTAGLANDIN J(2) WITH GLUTATHIONE, CATALYZED BY THE HUMAN GLUTATHIONE S-TRANSFERASES A1-1, A2-2, M1A-1A, AND P1-1
Authors: BOGAARDS JJP VENEKAMP JC VANBLADEREN PJ
Citation: Jjp. Bogaards et al., STEREOSELECTIVE CONJUGATION OF PROSTAGLANDIN A(2) AND PROSTAGLANDIN J(2) WITH GLUTATHIONE, CATALYZED BY THE HUMAN GLUTATHIONE S-TRANSFERASES A1-1, A2-2, M1A-1A, AND P1-1, Chemical research in toxicology, 10(3), 1997, pp. 310-317
INFLUENCE OF NONNUTRIENT PLANT-COMPONENTS ON BIOTRANSFORMATION ENZYMES
Authors: VANBLADEREN PJ
Citation: Pj. Vanbladeren, INFLUENCE OF NONNUTRIENT PLANT-COMPONENTS ON BIOTRANSFORMATION ENZYMES, Biomedicine & pharmacotherapy, 51(8), 1997, pp. 324-327
SUBACUTE TOXICITY OF A MIXTURE OF 9 CHEMICALS IN RATS - DETECTING INTERACTIVE EFFECTS WITH A FRACTIONATED 2-LEVEL FACTORIAL DESIGN
Authors: GROTEN JP SCHOEN ED VANBLADEREN PJ KUPER CF VANZORGE JA FERON VJ
Citation: Jp. Groten et al., SUBACUTE TOXICITY OF A MIXTURE OF 9 CHEMICALS IN RATS - DETECTING INTERACTIVE EFFECTS WITH A FRACTIONATED 2-LEVEL FACTORIAL DESIGN, Fundamental and applied toxicology, 36(1), 1997, pp. 15-29
URINARY THIODIACETIC ACID - A SELECTIVE BIOMARKER FOR THE CYTOCHROME P450-CATALYZED OXIDATION OF 1,2-DIBROMOETHANE IN THE RAT
Authors: WORMHOUDT LW COMMANDEUR JNM PLOEMEN JHTM ABDOELGAFOER RS MAKANSI A VANBLADEREN PJ VERMEULEN NPE
Citation: Lw. Wormhoudt et al., URINARY THIODIACETIC ACID - A SELECTIVE BIOMARKER FOR THE CYTOCHROME P450-CATALYZED OXIDATION OF 1,2-DIBROMOETHANE IN THE RAT, Drug metabolism and disposition, 25(4), 1997, pp. 508-515
INHIBITION OF GLUTATHIONE CONJUGATION BY GLUTATHIONE ANALOGS IN THE PERFUSED-RAT-LIVER - EFFECT OF ESTERIFICATION ON THE POTENCY OF L-GLUTAMYL-ALPHA-(D-2-AMINOADIPYL)-N-2-HEPTYLAMINE
Authors: OUWERKERKMAHADEVAN S TIRONA RG RIPPING RA PLOEMEN JHTM VANBLADEREN PJ PANG KS VANBOOM JH MULDER GJ
Citation: S. Ouwerkerkmahadevan et al., INHIBITION OF GLUTATHIONE CONJUGATION BY GLUTATHIONE ANALOGS IN THE PERFUSED-RAT-LIVER - EFFECT OF ESTERIFICATION ON THE POTENCY OF L-GLUTAMYL-ALPHA-(D-2-AMINOADIPYL)-N-2-HEPTYLAMINE, Drug metabolism and disposition, 25(10), 1997, pp. 1137-1143
A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PB-PK) MODEL FOR 1,2-DICHLOROBENZENE LINKED TO 2 POSSIBLE PARAMETERS OF TOXICITY
Authors: HISSINK AM VANOMMEN B KRUSE J VANBLADEREN PJ
Citation: Am. Hissink et al., A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PB-PK) MODEL FOR 1,2-DICHLOROBENZENE LINKED TO 2 POSSIBLE PARAMETERS OF TOXICITY, Toxicology and applied pharmacology, 145(2), 1997, pp. 301-310
SPECIES AND STRAIN DIFFERENCES IN THE HEPATIC CYTOCHROME P450-MEDIATED BIOTRANSFORMATION OF 1,4-DICHLOROBENZENE
Authors: HISSINK AM OUDSHOORN MJ VANOMMEN B VANBLADEREN PJ
Citation: Am. Hissink et al., SPECIES AND STRAIN DIFFERENCES IN THE HEPATIC CYTOCHROME P450-MEDIATED BIOTRANSFORMATION OF 1,4-DICHLOROBENZENE, Toxicology and applied pharmacology, 145(1), 1997, pp. 1-9
THE USE OF HUMAN IN-VITRO METABOLIC PARAMETERS TO EXPLORE THE RISK ASSESSMENT OF HAZARDOUS COMPOUNDS - THE CASE OF ETHYLENE DIBROMIDE
Authors: PLOEMEN JPHTM WORMHOUDT LW HAENEN GRMM OUDSHOORN MJ COMMANDEUR JNM VERMEULEN NPE DEWAZIERS I BEAUNE PH WATABE T VANBLADEREN PJ
Citation: Jphtm. Ploemen et al., THE USE OF HUMAN IN-VITRO METABOLIC PARAMETERS TO EXPLORE THE RISK ASSESSMENT OF HAZARDOUS COMPOUNDS - THE CASE OF ETHYLENE DIBROMIDE, Toxicology and applied pharmacology, 143(1), 1997, pp. 56-69
TRANSPORT OF GLUTATHIONE PROSTAGLANDIN-A CONJUGATES BY THE MULTIDRUG-RESISTANCE PROTEIN-1
Authors: EVERS R CNUBBEN NHP WIJNHOLDS J VANDEEMTER L VANBLADEREN PJ BORST P
Citation: R. Evers et al., TRANSPORT OF GLUTATHIONE PROSTAGLANDIN-A CONJUGATES BY THE MULTIDRUG-RESISTANCE PROTEIN-1, FEBS letters, 419(1), 1997, pp. 112-116
INTERACTIONS OF ALPHA,BETA-UNSATURATED ALDEHYDES AND KETONES WITH HUMAN GLUTATHIONE-S-TRANSFERASE P1-1
Authors: VANIERSEL MLPS PLOEMEN JPHTM LOBELLO M FEDERICI G VANBLADEREN PJ
Citation: Mlps. Vaniersel et al., INTERACTIONS OF ALPHA,BETA-UNSATURATED ALDEHYDES AND KETONES WITH HUMAN GLUTATHIONE-S-TRANSFERASE P1-1, Chemico-biological interactions, 108(1-2), 1997, pp. 67-78
KINETICS AND METABOLISM OF 1,4-DICHLOROBENZENE IN MALE WISTAR RATS - NO EVIDENCE FOR QUINONE METABOLITES
Authors: HISSINK AM DUNNEWIJK R VANOMMEN B VANBLADEREN PJ
Citation: Am. Hissink et al., KINETICS AND METABOLISM OF 1,4-DICHLOROBENZENE IN MALE WISTAR RATS - NO EVIDENCE FOR QUINONE METABOLITES, Chemico-biological interactions, 103(1), 1997, pp. 17-33
IDENTIFICATION OF MULTIPLE-TARGET SITES FOR A GLUTATHIONE CONJUGATE ON GLUTATHIONE-S-TRANSFERASE BY MATRIX-ASSISTED LASER DESORPTION IONIZATION MASS-SPECTROMETRY/
Authors: JESPERSEN S PLOEMEN JHTM VANBLADEREN PJ NIESSEN WMA TJADEN UR VANDERGREEF J
Citation: S. Jespersen et al., IDENTIFICATION OF MULTIPLE-TARGET SITES FOR A GLUTATHIONE CONJUGATE ON GLUTATHIONE-S-TRANSFERASE BY MATRIX-ASSISTED LASER DESORPTION IONIZATION MASS-SPECTROMETRY/, Journal of mass spectrometry., 31(1), 1996, pp. 101-107
DIFFERENCES IN CYTOCHROME P450-MEDIATED BIOTRANSFORMATION OF 1,2-DICHLOROBENZENE BY RAT AND MAN - IMPLICATIONS FOR HUMAN RISK ASSESSMENT
Authors: HISSINK AM OUDSHOORN MJ VANOMMEN P HAENEN GRMM VANBLADEREN PJ
Citation: Am. Hissink et al., DIFFERENCES IN CYTOCHROME P450-MEDIATED BIOTRANSFORMATION OF 1,2-DICHLOROBENZENE BY RAT AND MAN - IMPLICATIONS FOR HUMAN RISK ASSESSMENT, Chemical research in toxicology, 9(8), 1996, pp. 1249-1256
REGIOSELECTIVITY AND QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS FOR THE CONJUGATION OF A SERIES OF FLUORONITROBENZENES BY PURIFIED GLUTATHIONE-S-TRANSFERASE ENZYMES FROM RAT AND MAN
Authors: SOFFERS AEMF PLOEMEN JHTM MOONEN MJH WOBBES T VANOMMEN B VERVOORT J VANBLADEREN PJ RIETJENS IMCM
Citation: Aemf. Soffers et al., REGIOSELECTIVITY AND QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS FOR THE CONJUGATION OF A SERIES OF FLUORONITROBENZENES BY PURIFIED GLUTATHIONE-S-TRANSFERASE ENZYMES FROM RAT AND MAN, Chemical research in toxicology, 9(3), 1996, pp. 638-646
GLUTATHIONE CONJUGATION OF ALKYLATING CYTOSTATIC DRUGS WITH A NITROGEN-MUSTARD GROUP AND THE ROLE OF GLUTATHIONE S-TRANSFERASES
Authors: DIRVEN HAAM VANOMMEN B VANBLADEREN PJ
Citation: Haam. Dirven et al., GLUTATHIONE CONJUGATION OF ALKYLATING CYTOSTATIC DRUGS WITH A NITROGEN-MUSTARD GROUP AND THE ROLE OF GLUTATHIONE S-TRANSFERASES, Chemical research in toxicology, 9(2), 1996, pp. 351-360
METABOLISM OF TERT-BUTYLHYDROQUINONE TO S-SUBSTITUTED CONJUGATES IN THE MALE FISCHER-344 RAT
Authors: PETERS MMCG LAU SS DULIK D MURPHY D VANOMMEN B VANBLADEREN PJ MONKS TJ
Citation: Mmcg. Peters et al., METABOLISM OF TERT-BUTYLHYDROQUINONE TO S-SUBSTITUTED CONJUGATES IN THE MALE FISCHER-344 RAT, Chemical research in toxicology, 9(1), 1996, pp. 133-139
CYTOTOXICITY OF 2-TERT-BUTYL HYDROQUINONE GLUTATHIONE CONJUGATES AFTER APICAL AND BASOLATERAL EXPOSURE OF RAT RENAL PROXIMAL TUBULAR CELL MONOLAYERS
Authors: HAENEN HEMG BLEIJLEVENS E ELZERMAN H TEMMINK JHM KOEMAN JH VANBLADEREN PJ
Citation: Hemg. Haenen et al., CYTOTOXICITY OF 2-TERT-BUTYL HYDROQUINONE GLUTATHIONE CONJUGATES AFTER APICAL AND BASOLATERAL EXPOSURE OF RAT RENAL PROXIMAL TUBULAR CELL MONOLAYERS, Toxicology in vitro, 10(2), 1996, pp. 141-148
TRANSPORT AND METABOLISM OF GLUTATHIONE CONJUGATES OF MENADIONE AND ETHACRYNIC-ACID IN CONFLUENT MONOLAYERS OF RAT RENAL PROXIMAL TUBULAR CELLS
Authors: HAENEN HEMG SPENKELINK A TEUNISSEN C TEMMINK JHM KOEMAN JH VANBLADEREN PJ
Citation: Hemg. Haenen et al., TRANSPORT AND METABOLISM OF GLUTATHIONE CONJUGATES OF MENADIONE AND ETHACRYNIC-ACID IN CONFLUENT MONOLAYERS OF RAT RENAL PROXIMAL TUBULAR CELLS, Toxicology, 112(2), 1996, pp. 117-130
ENZYME-KINETICS AND SUBSTRATE SELECTIVITIES OF RAT GLUTATHIONE-S-TRANSFERASE ISOENZYMES TOWARDS A SERIES OF NEW 2-SUBSTITUTED 1-CHLORO-4-NITROBENZENES
Authors: VANDERAAR EM BUIKEMA D COMMANDEUR JNM TEKOPPELE JM VANOMMEN B VANBLADEREN PJ VERMEULEN NPE
Citation: Em. Vanderaar et al., ENZYME-KINETICS AND SUBSTRATE SELECTIVITIES OF RAT GLUTATHIONE-S-TRANSFERASE ISOENZYMES TOWARDS A SERIES OF NEW 2-SUBSTITUTED 1-CHLORO-4-NITROBENZENES, Xenobiotica, 26(2), 1996, pp. 143-155
Risultati: 1-25 | 26-50 | 51-69