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Results: 1-25 | 26-31
Results: 1-25/31
DISPOSITION OF [C-14]GAMMA-CYCLODEXTRIN IN GERM-FREE AND CONVENTIONALRATS
Authors: DEBIE ATHJ VANOMMEN B BAR A
Citation: Athj. Debie et al., DISPOSITION OF [C-14]GAMMA-CYCLODEXTRIN IN GERM-FREE AND CONVENTIONALRATS, Regulatory toxicology and pharmacology, 27(2), 1998, pp. 150-158
A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PB-PK) MODEL FOR 1,2-DICHLOROBENZENE LINKED TO 2 POSSIBLE PARAMETERS OF TOXICITY
Authors: HISSINK AM VANOMMEN B KRUSE J VANBLADEREN PJ
Citation: Am. Hissink et al., A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PB-PK) MODEL FOR 1,2-DICHLOROBENZENE LINKED TO 2 POSSIBLE PARAMETERS OF TOXICITY, Toxicology and applied pharmacology, 145(2), 1997, pp. 301-310
SPECIES AND STRAIN DIFFERENCES IN THE HEPATIC CYTOCHROME P450-MEDIATED BIOTRANSFORMATION OF 1,4-DICHLOROBENZENE
Authors: HISSINK AM OUDSHOORN MJ VANOMMEN B VANBLADEREN PJ
Citation: Am. Hissink et al., SPECIES AND STRAIN DIFFERENCES IN THE HEPATIC CYTOCHROME P450-MEDIATED BIOTRANSFORMATION OF 1,4-DICHLOROBENZENE, Toxicology and applied pharmacology, 145(1), 1997, pp. 1-9
KINETICS AND METABOLISM OF 1,4-DICHLOROBENZENE IN MALE WISTAR RATS - NO EVIDENCE FOR QUINONE METABOLITES
Authors: HISSINK AM DUNNEWIJK R VANOMMEN B VANBLADEREN PJ
Citation: Am. Hissink et al., KINETICS AND METABOLISM OF 1,4-DICHLOROBENZENE IN MALE WISTAR RATS - NO EVIDENCE FOR QUINONE METABOLITES, Chemico-biological interactions, 103(1), 1997, pp. 17-33
REGIOSELECTIVITY AND QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS FOR THE CONJUGATION OF A SERIES OF FLUORONITROBENZENES BY PURIFIED GLUTATHIONE-S-TRANSFERASE ENZYMES FROM RAT AND MAN
Authors: SOFFERS AEMF PLOEMEN JHTM MOONEN MJH WOBBES T VANOMMEN B VERVOORT J VANBLADEREN PJ RIETJENS IMCM
Citation: Aemf. Soffers et al., REGIOSELECTIVITY AND QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS FOR THE CONJUGATION OF A SERIES OF FLUORONITROBENZENES BY PURIFIED GLUTATHIONE-S-TRANSFERASE ENZYMES FROM RAT AND MAN, Chemical research in toxicology, 9(3), 1996, pp. 638-646
GLUTATHIONE CONJUGATION OF ALKYLATING CYTOSTATIC DRUGS WITH A NITROGEN-MUSTARD GROUP AND THE ROLE OF GLUTATHIONE S-TRANSFERASES
Authors: DIRVEN HAAM VANOMMEN B VANBLADEREN PJ
Citation: Haam. Dirven et al., GLUTATHIONE CONJUGATION OF ALKYLATING CYTOSTATIC DRUGS WITH A NITROGEN-MUSTARD GROUP AND THE ROLE OF GLUTATHIONE S-TRANSFERASES, Chemical research in toxicology, 9(2), 1996, pp. 351-360
METABOLISM OF TERT-BUTYLHYDROQUINONE TO S-SUBSTITUTED CONJUGATES IN THE MALE FISCHER-344 RAT
Authors: PETERS MMCG LAU SS DULIK D MURPHY D VANOMMEN B VANBLADEREN PJ MONKS TJ
Citation: Mmcg. Peters et al., METABOLISM OF TERT-BUTYLHYDROQUINONE TO S-SUBSTITUTED CONJUGATES IN THE MALE FISCHER-344 RAT, Chemical research in toxicology, 9(1), 1996, pp. 133-139
DISPOSITION OF C-14 ERYTHRITOL IN GERM-FREE AND CONVENTIONAL RATS
Authors: VANOMMEN B DEBIE B BAR A
Citation: B. Vanommen et al., DISPOSITION OF C-14 ERYTHRITOL IN GERM-FREE AND CONVENTIONAL RATS, Regulatory toxicology and pharmacology, 24(2), 1996, pp. 198-205
ENZYME-KINETICS AND SUBSTRATE SELECTIVITIES OF RAT GLUTATHIONE-S-TRANSFERASE ISOENZYMES TOWARDS A SERIES OF NEW 2-SUBSTITUTED 1-CHLORO-4-NITROBENZENES
Authors: VANDERAAR EM BUIKEMA D COMMANDEUR JNM TEKOPPELE JM VANOMMEN B VANBLADEREN PJ VERMEULEN NPE
Citation: Em. Vanderaar et al., ENZYME-KINETICS AND SUBSTRATE SELECTIVITIES OF RAT GLUTATHIONE-S-TRANSFERASE ISOENZYMES TOWARDS A SERIES OF NEW 2-SUBSTITUTED 1-CHLORO-4-NITROBENZENES, Xenobiotica, 26(2), 1996, pp. 143-155
DOSE-DEPENDENT KINETICS AND METABOLISM OF 1,2-DICHLOROBENZENE IN RAT - EFFECT OF PRETREATMENT WITH PHENOBARBITAL
Authors: HISSINK AM VANOMMEN B VANBLADEREN PJ
Citation: Am. Hissink et al., DOSE-DEPENDENT KINETICS AND METABOLISM OF 1,2-DICHLOROBENZENE IN RAT - EFFECT OF PRETREATMENT WITH PHENOBARBITAL, Xenobiotica, 26(1), 1996, pp. 89-105
CYTOCHROME-P450 CATALYZED METABOLISM OF 1,2-DIBROMOETHANE IN LIVER-MICROSOMES OF DIFFERENTIALLY INDUCED RATS
Authors: WORMHOUDT LW PLOEMEN JHTM COMMANDEUR JNM VANOMMEN B VANBLADEREN PJ VERMEULEN NPE
Citation: Lw. Wormhoudt et al., CYTOCHROME-P450 CATALYZED METABOLISM OF 1,2-DIBROMOETHANE IN LIVER-MICROSOMES OF DIFFERENTIALLY INDUCED RATS, Chemico-biological interactions, 99(1-3), 1996, pp. 41-53
COMPARATIVE BIOTRANSFORMATION OF HEXACHLOROBENZENE AND HEXAFLUOROBENZENE IN RELATION TO THE INDUCTION OF PORPHYRIA
Authors: RIETJENS IMCM STEENSMA A DENBESTEN C VANTINTELEN G HAAS J VANOMMEN B VANBLADEREN PJ
Citation: Imcm. Rietjens et al., COMPARATIVE BIOTRANSFORMATION OF HEXACHLOROBENZENE AND HEXAFLUOROBENZENE IN RELATION TO THE INDUCTION OF PORPHYRIA, European journal of pharmacology. Environmental toxicology and pharmacology section, 293(4), 1995, pp. 293-299
GLUTATHIONE CONJUGATION OF THE CYTOSTATIC DRUG IFOSFAMIDE AND THE ROLE OF HUMAN GLUTATHIONE S-TRANSFERASES
Authors: DIRVEN HAAM MEGENS L OUDSHOORN MJ DINGEMANSE MA VANOMMEN B VANBLADEREN PJ
Citation: Haam. Dirven et al., GLUTATHIONE CONJUGATION OF THE CYTOSTATIC DRUG IFOSFAMIDE AND THE ROLE OF HUMAN GLUTATHIONE S-TRANSFERASES, Chemical research in toxicology, 8(7), 1995, pp. 979-986
METABOLISM AND KINETICS OF TRICHLOROETHYLENE IN RELATION TO TOXICITY AND CARCINOGENICITY - RELEVANCE OF THE MERCAPTURIC ACID PATHWAY
Authors: GOEPTAR AR COMMANDEUR JNM VANOMMEN B VANBLADEREN PJ VERMEULEN NPE
Citation: Ar. Goeptar et al., METABOLISM AND KINETICS OF TRICHLOROETHYLENE IN RELATION TO TOXICITY AND CARCINOGENICITY - RELEVANCE OF THE MERCAPTURIC ACID PATHWAY, Chemical research in toxicology, 8(1), 1995, pp. 3-21
COMPUTER-AIDED BIOKINETIC MODELING COMBINED WITH IN-VITRO DATA
Authors: VANOMMEN B DEJONGH J VANDESANDT J BLAAUBOER B HISSINK E BOGAARDS J VANBLADEREN P
Citation: B. Vanommen et al., COMPUTER-AIDED BIOKINETIC MODELING COMBINED WITH IN-VITRO DATA, Toxicology in vitro, 9(4), 1995, pp. 537-542
POLYMORPHISM IN THE GLUTATHIONE CONJUGATION ACTIVITY OF HUMAN ERYTHROCYTES TOWARDS ETHYLENE DIBROMIDE AND 1,2-EPOXY-3-(P-NITROPHENOXY)-PROPANE
Authors: PLOEMEN JHTM WORMHOUDT LW VANOMMEN B COMMANDEUR JNM VERMEULEN NPE VANBLADEREN PJ
Citation: Jhtm. Ploemen et al., POLYMORPHISM IN THE GLUTATHIONE CONJUGATION ACTIVITY OF HUMAN ERYTHROCYTES TOWARDS ETHYLENE DIBROMIDE AND 1,2-EPOXY-3-(P-NITROPHENOXY)-PROPANE, Biochimica et biophysica acta (G). General subjects, 1243(3), 1995, pp. 469-476
METABOLIC DISPOSITION IN RATS OF REGULAR AND ENZYMATICALLY DEPOLYMERIZED SODIUM CARBOXYMETHYLCELLULOSE
Authors: BAR A VANOMMEN B TIMONEN M
Citation: A. Bar et al., METABOLIC DISPOSITION IN RATS OF REGULAR AND ENZYMATICALLY DEPOLYMERIZED SODIUM CARBOXYMETHYLCELLULOSE, Food and chemical toxicology, 33(11), 1995, pp. 901-907
HUMAN CYTOCHROME-P450 ENZYME SELECTIVITIES IN THE OXIDATION OF CHLORINATED BENZENES
Authors: BOGAARDS JJP VANOMMEN B WOLF CR VANBLADEREN PJ
Citation: Jjp. Bogaards et al., HUMAN CYTOCHROME-P450 ENZYME SELECTIVITIES IN THE OXIDATION OF CHLORINATED BENZENES, Toxicology and applied pharmacology, 132(1), 1995, pp. 44-52
THE ROLE OF HUMAN GLUTATHIONE-S-TRANSFERASE ISOENZYMES IN THE FORMATION OF GLUTATHIONE CONJUGATES OF THE ALKYLATING CYTOSTATIC DRUG THIOTEPA
Authors: DIRVEN HAAM DICTUS ELJT BROEDERS NLHL VANOMMEN B VANBLADEREN PJ
Citation: Haam. Dirven et al., THE ROLE OF HUMAN GLUTATHIONE-S-TRANSFERASE ISOENZYMES IN THE FORMATION OF GLUTATHIONE CONJUGATES OF THE ALKYLATING CYTOSTATIC DRUG THIOTEPA, Cancer research, 55(8), 1995, pp. 1701-1706
ACTIVE-SITE TYROSYL RESIDUES ARE TARGETS IN THE IRREVERSIBLE INHIBITION OF A CLASS MU-GLUTATHIONE TRANSFERASE BY -(S-GLUTATHIONYL)-3,5,6-TRICHLORO-1,4-BENZOQUINONE
Authors: PLOEMEN JHTM JOHNSON WW JESPERSEN S VANDERWALL D VANOMMEN B VANDERGREEF J VANBLADEREN PJ ARMSTRONG RN
Citation: Jhtm. Ploemen et al., ACTIVE-SITE TYROSYL RESIDUES ARE TARGETS IN THE IRREVERSIBLE INHIBITION OF A CLASS MU-GLUTATHIONE TRANSFERASE BY -(S-GLUTATHIONYL)-3,5,6-TRICHLORO-1,4-BENZOQUINONE, The Journal of biological chemistry, 269(43), 1994, pp. 26890-26897
THE INTERACTION OF GLUTATHIONE WITH 4-HYDROXYCYCLOPHOSPHAMIDE AND PHOSPHORAMIDE MUSTARD, STUDIED BY P-31 NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY
Authors: DIRVEN HAAM VENEKAMP JC VANOMMEN B VANBLADEREN PJ
Citation: Haam. Dirven et al., THE INTERACTION OF GLUTATHIONE WITH 4-HYDROXYCYCLOPHOSPHAMIDE AND PHOSPHORAMIDE MUSTARD, STUDIED BY P-31 NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY, Chemico-biological interactions, 93(3), 1994, pp. 185-196
INHIBITION OF HUMAN GLUTATHIONE S-TRANSFERASES BY DOPAMINE, ALPHA-METHYLDOPA AND THEIR 5-S-GLUTATHIONYL CONJUGATES
Authors: PLOEMEN JHTM VANOMMEN B DEHAAN A VENEKAMP JC VANBLADEREN PJ
Citation: Jhtm. Ploemen et al., INHIBITION OF HUMAN GLUTATHIONE S-TRANSFERASES BY DOPAMINE, ALPHA-METHYLDOPA AND THEIR 5-S-GLUTATHIONYL CONJUGATES, Chemico-biological interactions, 90(1), 1994, pp. 87-99
REVERSIBLE CONJUGATION OF ETHACRYNIC-ACID WITH GLUTATHIONE AND HUMAN GLUTATHIONE-S-TRANSFERASE P1-1
Authors: PLOEMEN JHTM VANSCHANKE A VANOMMEN B VANBLADEREN PJ
Citation: Jhtm. Ploemen et al., REVERSIBLE CONJUGATION OF ETHACRYNIC-ACID WITH GLUTATHIONE AND HUMAN GLUTATHIONE-S-TRANSFERASE P1-1, Cancer research, 54(4), 1994, pp. 915-919
INVOLVEMENT OF HUMAN GLUTATHIONE-S-TRANSFERASE ISOENZYMES IN THE CONJUGATION OF CYCLOPHOSPHAMIDE METABOLITES WITH GLUTATHIONE
Authors: DIRVEN HAAM VANOMMEN B VANBLADEREN PJ
Citation: Haam. Dirven et al., INVOLVEMENT OF HUMAN GLUTATHIONE-S-TRANSFERASE ISOENZYMES IN THE CONJUGATION OF CYCLOPHOSPHAMIDE METABOLITES WITH GLUTATHIONE, Cancer research, 54(23), 1994, pp. 6215-6220
BIOTRANSFORMATION OF 1,2-DIHYDRONAPHTHALENE AND 1,2-DIHYDROANTHRACENEBY RAT-LIVER MICROSOMES AND PURIFIED CYTOCHROMES P-450 - FORMATION OFARENE HYDRATES OF NAPHTHALENE AND ANTHRACENE
Authors: BOYD DR SHARMA ND AGARWAL R MCMORDIE RAS BESSEMS JGM VANOMMEN B VANBLADEREN PJ
Citation: Dr. Boyd et al., BIOTRANSFORMATION OF 1,2-DIHYDRONAPHTHALENE AND 1,2-DIHYDROANTHRACENEBY RAT-LIVER MICROSOMES AND PURIFIED CYTOCHROMES P-450 - FORMATION OFARENE HYDRATES OF NAPHTHALENE AND ANTHRACENE, Chemical research in toxicology, 6(6), 1993, pp. 808-812
Risultati: 1-25 | 26-31