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Results: 1-14 |
Results: 14
HUMAN SERUM ATTENUATES THE ACTIVITY OF PROTEASE INHIBITORS TOWARD WILD-TYPE AND MUTANT HUMAN-IMMUNODEFICIENCY-VIRUS
Authors: MOLLA A VASAVANONDA S KUMAR G SHAM HL JOHNSON M GRABOWSKI B DENISSEN JF KOHLBRENNER W PLATTNER JJ LEONARD JM NORBECK DW KEMPF DJ
Citation: A. Molla et al., HUMAN SERUM ATTENUATES THE ACTIVITY OF PROTEASE INHIBITORS TOWARD WILD-TYPE AND MUTANT HUMAN-IMMUNODEFICIENCY-VIRUS, Virology (New York, N.Y. Print), 250(2), 1998, pp. 255-262
DISCOVERY OF RITONAVIR, A POTENT INHIBITOR OF HIV PROTEASE WITH HIGH ORAL BIOAVAILABILITY AND CLINICAL EFFICACY
Authors: KEMPF DJ SHAM HL MARSH KC FLENTGE CA BETEBENNER D GREEN BE MCDONALD E VASAVANONDA S SALDIVAR A WIDEBURG NE KATI WM RUIZ L ZHAO C FINO LM PATTERSON J MOLLA A PLATTNER JJ NORBECK DW
Citation: Dj. Kempf et al., DISCOVERY OF RITONAVIR, A POTENT INHIBITOR OF HIV PROTEASE WITH HIGH ORAL BIOAVAILABILITY AND CLINICAL EFFICACY, Journal of medicinal chemistry, 41(4), 1998, pp. 602-617
LACK OF STEREOSPECIFICITY IN THE BINDING OF THE P2 AMINO-ACID OF RITONAVIR TO HIV PROTEASE
Authors: KEMPF DJ MOLLA A MARSH KC PARK C RODRIGUES AD KORNEYEVA M VASAVANONDA S MCDONALD E FLENTGE CA MUCHMORE S WIDEBURG NE SALDIVAR A COOPER A KATI WM STEWART KD NORBECK DW
Citation: Dj. Kempf et al., LACK OF STEREOSPECIFICITY IN THE BINDING OF THE P2 AMINO-ACID OF RITONAVIR TO HIV PROTEASE, Bioorganic & medicinal chemistry letters, 7(6), 1997, pp. 699-704
ORDERED ACCUMULATION OF MUTATIONS IN HIV PROTEASE CONFERS RESISTANCE TO RITONAVIR
Authors: MOLLA A KORNEYEVA M GAO Q VASAVANONDA S SCHIPPER PJ MO HM MARKOWITZ M CHERNYAVSKIY T NIU P LYONS N HSU A GRANNEMAN GR HO DD BOUCHER CAB LEONARD JM NORBECK DW KEMPF DJ
Citation: A. Molla et al., ORDERED ACCUMULATION OF MUTATIONS IN HIV PROTEASE CONFERS RESISTANCE TO RITONAVIR, Nature medicine, 2(7), 1996, pp. 760-766
EVALUATION OF FUROFURAN AS A P-2 LIGAND FOR SYMMETRY-BASED HIV PROTEASE INHIBITORS
Authors: CHEN XQ LI L KEMPF DJ SHAM H WIDEBURG NE SALDIVAR A VASAVANONDA S MARSH KC MCDONALD E NORBECK DW
Citation: Xq. Chen et al., EVALUATION OF FUROFURAN AS A P-2 LIGAND FOR SYMMETRY-BASED HIV PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 6(23), 1996, pp. 2847-2852
A NOVEL, PICOMOLAR INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASES
Authors: SHAM HL ZHAO C STEWART KD BETEBENNER DA LIN SQ PARK CH KONG XP ROSENBROOK W HERRIN T MADIGAN D VASAVANONDA S LYONS N MOLLA A SALDIVAR A MARSH KC MCDONALD E WIDEBURG NE DENISSEN JF ROBINS T KEMPF DJ PLATTNER JJ NORBECK DW
Citation: Hl. Sham et al., A NOVEL, PICOMOLAR INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PROTEASES, Journal of medicinal chemistry, 39(2), 1996, pp. 392-397
NOVEL AZACYCLIC UREAS THAT ARE POTENT INHIBITORS OF HIV-1 PROTEASE
Authors: SHAM HL ZHAO C MARSH KC BETEBENNER DA LIN SQ ROSENBROOK W HERRIN T LI LP MADIGAN D VASAVANONDA S MOLLA A SALDIVAR A MCDONALD E WIDEBURG NE KEMPF D NORBECK DW PLATTNER JJ
Citation: Hl. Sham et al., NOVEL AZACYCLIC UREAS THAT ARE POTENT INHIBITORS OF HIV-1 PROTEASE, Biochemical and biophysical research communications, 225(2), 1996, pp. 436-440
EVOLUTION OF RESISTANCE TO THE PROTEASE INHIBITOR RITONAVIR (ABT-538)IN HIV-INFECTED PATIENTS
Authors: MOLLA A BOUCHER C KORNEYEVA M GAO Q SCHIPPER P LYONS N VASAVANONDA S NIU P STEWART K PARK C CHERNYAVSKIY T KEMPF D LEONARD J NORBECK D
Citation: A. Molla et al., EVOLUTION OF RESISTANCE TO THE PROTEASE INHIBITOR RITONAVIR (ABT-538)IN HIV-INFECTED PATIENTS, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 69-69
EVALUATION OF SUBSTITUTED BENZAMIDES AS P2 LIGANDS FOR SYMMETRY-BASEDINHIBITORS OF HIV PROTEASE
Authors: KEMPF DJ FLENTGE CA WIDEBURG NE SALDIVAR A VASAVANONDA S NORBECK DW
Citation: Dj. Kempf et al., EVALUATION OF SUBSTITUTED BENZAMIDES AS P2 LIGANDS FOR SYMMETRY-BASEDINHIBITORS OF HIV PROTEASE, Bioorganic & medicinal chemistry letters, 5(22), 1995, pp. 2725-2728
ABT-538 IS A POTENT INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE AND HAS HIGH ORAL BIOAVAILABILITY IN HUMANS
Authors: KEMPF DJ MARSH KC DENISSEN JF MCDONALD E VASAVANONDA S FLENTGE CA GREEN BE FINO L PARK CH KONG XP WIDEBURG NE SALDIVAR A RUIZ L KATI WM SHAM HL ROBINS T STEWART KD HSU A PLATTNER JJ LEONARD JM NORBECK DW
Citation: Dj. Kempf et al., ABT-538 IS A POTENT INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS PROTEASE AND HAS HIGH ORAL BIOAVAILABILITY IN HUMANS, Proceedings of the National Academy of Sciences of the United Statesof America, 92(7), 1995, pp. 2484-2488
POTENT INHIBITORS OF THE HIV-1 PROTEASE WITH GOOD ORAL BIOAVAILABILITIES
Authors: SHAM HL ZHAO C MARSH KC BETEBENNER DA LIN SQ MCDONALD E VASAVANONDA S WIDEBURG N SALDIVAR A ROBINS T KEMPF DJ PLATTNER JJ NORBECK DW
Citation: Hl. Sham et al., POTENT INHIBITORS OF THE HIV-1 PROTEASE WITH GOOD ORAL BIOAVAILABILITIES, Biochemical and biophysical research communications, 211(1), 1995, pp. 159-165
SYMMETRY-BASED INHIBITORS OF HIV PROTEASE - ORAL BIOAVAILABILITY AND RESISTANCE EMERGENCE
Authors: KEMPF DJ FLENTGE C MARSH KC MCDONALD E ROBINS T VASAVANONDA S CHEN CM WIDEBURG NE PARK C KONG XP DENISSEN J HO DD MARKOWITZ M TOYOSHIMA T SINGH MK ERICKSON J SHAM HL STEWART K GREEN BE TURON M SALDIVAR A NORBECK DW
Citation: Dj. Kempf et al., SYMMETRY-BASED INHIBITORS OF HIV PROTEASE - ORAL BIOAVAILABILITY AND RESISTANCE EMERGENCE, Journal of cellular biochemistry, 1994, pp. 130-130
BIOCHEMICAL-CHARACTERIZATION OF HIV-1 PROTEASE MUTANTS RESISTANT TO A-77003, A-80987
Authors: CHEN CM SALDIVAR A TURON M WIDEBURG NE ROBINS T VASAVANONDA S STEWART K PARK C KONG XP KEMPF DJ HO D ERICKSON J NORBECK DW
Citation: Cm. Chen et al., BIOCHEMICAL-CHARACTERIZATION OF HIV-1 PROTEASE MUTANTS RESISTANT TO A-77003, A-80987, Journal of cellular biochemistry, 1994, pp. 166-166
PSEUDO-SYMMETRICAL DIFLUOROKETONES - HIGHLY POTENT AND SPECIFIC INHIBITORS OF HIV-1 PROTEASE
Authors: SHAM HL BETEBENNER DA WIDEBURG N SALDIVAR AC KOHLBRENNER WE CRAIGKENNARD A VASAVANONDA S KEMPF DJ CLEMENT JJ ERICKSON JE PLATTNER JJ NORBECK DW
Citation: Hl. Sham et al., PSEUDO-SYMMETRICAL DIFLUOROKETONES - HIGHLY POTENT AND SPECIFIC INHIBITORS OF HIV-1 PROTEASE, FEBS letters, 329(1-2), 1993, pp. 144-146
Risultati: 1-14 |