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Results: 1-25 | 26-42
Results: 1-25/42
EFFICACY, SAFETY AND MECHANISM OF CYCLODEXTRINS AS ABSORPTION ENHANCERS IN NASAL DELIVERY OF PEPTIDE AND PROTEIN DRUGS
Authors: MARTTIN E VERHOEF JC MERKUS FWHM
Citation: E. Marttin et al., EFFICACY, SAFETY AND MECHANISM OF CYCLODEXTRINS AS ABSORPTION ENHANCERS IN NASAL DELIVERY OF PEPTIDE AND PROTEIN DRUGS, Journal of drug targeting, 6(1), 1998, pp. 17-36
NASAL MUCOCILIARY CLEARANCE AS A FACTOR IN NASAL DRUG-DELIVERY
Authors: MARTTIN E SCHIPPER NGM VERHOEF JC MERKUS FWHM
Citation: E. Marttin et al., NASAL MUCOCILIARY CLEARANCE AS A FACTOR IN NASAL DRUG-DELIVERY, Advanced drug delivery reviews, 29(1-2), 1998, pp. 13-38
COMPARISON OF THE EFFECT OF DIFFERENT CHITOSAN SALTS AND N-TRIMETHYL CHITOSAN CHLORIDE ON THE PERMEABILITY OF INTESTINAL EPITHELIAL-CELLS (CACO-2)
Authors: KOTZE AF LUESSEN HL DELEEUW BJ DEBOER BG VERHOEF JC JUNGINGER HE
Citation: Af. Kotze et al., COMPARISON OF THE EFFECT OF DIFFERENT CHITOSAN SALTS AND N-TRIMETHYL CHITOSAN CHLORIDE ON THE PERMEABILITY OF INTESTINAL EPITHELIAL-CELLS (CACO-2), Journal of controlled release, 51(1), 1998, pp. 35-46
SIMPLIFIED SOLID-PHASE EXTRACTION METHOD FOR DETERMINATION OF DIHYDROERGOTAMINE IN RABBIT AND HUMAN SERUM USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH FLUORESCENCE DETECTION
Authors: ROMEIJN SG MARTTIN E VERHOEF JC MERKUS FWHM
Citation: Sg. Romeijn et al., SIMPLIFIED SOLID-PHASE EXTRACTION METHOD FOR DETERMINATION OF DIHYDROERGOTAMINE IN RABBIT AND HUMAN SERUM USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH FLUORESCENCE DETECTION, Journal of chromatography B. Biomedical sciences and applications, 692(1), 1997, pp. 227-232
ELECTROPERTURBATION OF THE HUMAN SKIN BARRIER IN-VITRO .2. EFFECTS ONSTRATUM-CORNEUM LIPID ORDERING AND ULTRASTRUCTURE
Authors: CRAANEVANHINSBERG IWHM VERHOEF JC SPIES F BOUWSTRA JA GOORIS GS JUNGINGER HE BODDE HE
Citation: Iwhm. Craanevanhinsberg et al., ELECTROPERTURBATION OF THE HUMAN SKIN BARRIER IN-VITRO .2. EFFECTS ONSTRATUM-CORNEUM LIPID ORDERING AND ULTRASTRUCTURE, Microscopy research and technique, 37(3), 1997, pp. 200-213
EFFECTS OF THE PENETRATION ENHANCER GLYCODEOXYCHOLATE ON THE LIPID INTEGRITY IN PORCINE BUCCAL EPITHELIUM IN-VITRO
Authors: HOOGSTRAATE AJ WERTZ PW SQUIER CA BOSVANGEEST A ABRAHAM W GARRISON MD VERHOEF JC JUNGINGER HE BODDE HE
Citation: Aj. Hoogstraate et al., EFFECTS OF THE PENETRATION ENHANCER GLYCODEOXYCHOLATE ON THE LIPID INTEGRITY IN PORCINE BUCCAL EPITHELIUM IN-VITRO, European journal of pharmaceutical sciences, 5(4), 1997, pp. 189-198
N-TRIMETHYL CHITOSAN CHLORIDE AS A POTENTIAL ABSORPTION ENHANCER ACROSS MUCOSAL SURFACES - IN-VITRO EVALUATION IN INTESTINAL EPITHELIAL-CELLS (CACO-2)
Authors: KOTZE AF LUESSEN HL DELEEUW BJ DEBOER BG VERHOEF JC JUNGINGER HE
Citation: Af. Kotze et al., N-TRIMETHYL CHITOSAN CHLORIDE AS A POTENTIAL ABSORPTION ENHANCER ACROSS MUCOSAL SURFACES - IN-VITRO EVALUATION IN INTESTINAL EPITHELIAL-CELLS (CACO-2), Pharmaceutical research, 14(9), 1997, pp. 1197-1202
CONFOCAL LASER-SCANNING MICROSCOPIC VISUALIZATION OF THE TRANSPORT OFDEXTRANS AFTER NASAL ADMINISTRATION TO RATS - EFFECTS OF ABSORPTION ENHANCERS
Authors: MARTTIN E VERHOEF JC CULLANDER C ROMEIJN SG NAGELKERKE JF MERKUS FWHM
Citation: E. Marttin et al., CONFOCAL LASER-SCANNING MICROSCOPIC VISUALIZATION OF THE TRANSPORT OFDEXTRANS AFTER NASAL ADMINISTRATION TO RATS - EFFECTS OF ABSORPTION ENHANCERS, Pharmaceutical research, 14(5), 1997, pp. 631-637
CHITOSANS FOR ENHANCED DELIVERY OF THERAPEUTIC PEPTIDES ACROSS INTESTINAL EPITHELIA - IN-VITRO EVALUATION IN CACO-2 CELL MONOLAYERS
Authors: KOTZE AF DELEEUW BJ LUESSEN HL DEBOER AG VERHOEF JC JUNGINGER HE
Citation: Af. Kotze et al., CHITOSANS FOR ENHANCED DELIVERY OF THERAPEUTIC PEPTIDES ACROSS INTESTINAL EPITHELIA - IN-VITRO EVALUATION IN CACO-2 CELL MONOLAYERS, International journal of pharmaceutics, 159(2), 1997, pp. 243-253
MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .4. POLYCARBOPHIL AND CHITOSAN ARE POTENT ENHANCERS OF PEPTIDE-TRANSPORT ACROSS INTESTINAL MUCOSAE IN-VITRO
Authors: LUESSEN HL RENTEL CO KOTZE AF LEHR CM DEBOER AG VERHOEF JC JUNGINGER HE
Citation: Hl. Luessen et al., MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .4. POLYCARBOPHIL AND CHITOSAN ARE POTENT ENHANCERS OF PEPTIDE-TRANSPORT ACROSS INTESTINAL MUCOSAE IN-VITRO, Journal of controlled release, 45(1), 1997, pp. 15-23
NASAL ABSORPTION OF DIHYDROERGOTAMINE FROM LIQUID AND POWDER FORMULATIONS IN RABBITS
Authors: MARTTIN E ROMEIJN SG VERHOEF JC MERKUS FWHM
Citation: E. Marttin et al., NASAL ABSORPTION OF DIHYDROERGOTAMINE FROM LIQUID AND POWDER FORMULATIONS IN RABBITS, Journal of pharmaceutical sciences, 86(7), 1997, pp. 802-807
DISINTEGRATION AND GEL-FORMING BEHAVIOR OF CARBOMER AND ITS SODIUM-SALT USED AS EXCIPIENTS FOR DIRECT COMPRESSION
Authors: KAIHO F LUESSEN HL LEHR CM VERHOEF JC JUNGINGER HE
Citation: F. Kaiho et al., DISINTEGRATION AND GEL-FORMING BEHAVIOR OF CARBOMER AND ITS SODIUM-SALT USED AS EXCIPIENTS FOR DIRECT COMPRESSION, STP pharma sciences, 6(6), 1996, pp. 385-389
MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .1. INFLUENCE OF MUCOADHESIVE EXCIPIENTS ON THE PROTEOLYTIC ACTIVITY OF INTESTINAL ENZYMES
Authors: LUESSEN HL DELEEUW BJ PERARD D LEHR CM DEBOER ABG VERHOEF JC JUNGINGER HE
Citation: Hl. Luessen et al., MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .1. INFLUENCE OF MUCOADHESIVE EXCIPIENTS ON THE PROTEOLYTIC ACTIVITY OF INTESTINAL ENZYMES, European journal of pharmaceutical sciences, 4(2), 1996, pp. 117-128
IN-VIVO BUCCAL DELIVERY OF THE PEPTIDE DRUG BUSERELIN WITH GLYCODEOXYCHOLATE AS AN ABSORPTION ENHANCER IN PIGS
Authors: HOOGSTRAATE AJ VERHOEF JC PIJPERS A VANLEENGOED LAMG VERHEIJDEN JHM JUNGINGER HE BODDE HE
Citation: Aj. Hoogstraate et al., IN-VIVO BUCCAL DELIVERY OF THE PEPTIDE DRUG BUSERELIN WITH GLYCODEOXYCHOLATE AS AN ABSORPTION ENHANCER IN PIGS, Pharmaceutical research, 13(8), 1996, pp. 1233-1237
MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .6. CARBOMER AND CHITOSAN IMPROVE THE INTESTINAL-ABSORPTION OF THE PEPTIDE DRUG BUSERELIN IN-VIVO
Authors: LUESSEN HL DELEEUW BJ LANGEMEYER MWE DEBOER AG VERHOEF JC JUNGINGER HE
Citation: Hl. Luessen et al., MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .6. CARBOMER AND CHITOSAN IMPROVE THE INTESTINAL-ABSORPTION OF THE PEPTIDE DRUG BUSERELIN IN-VIVO, Pharmaceutical research, 13(11), 1996, pp. 1668-1672
MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .5. EFFECT OF POLY(ACRYLATES) ON THE ENZYMATIC DEGRADATION OF PEPTIDE DRUGS BY INTESTINAL BRUSH-BORDER MEMBRANE-VESICLES
Authors: LUESSEN HL BOHNER V PERARD D LANGGUTH P VERHOEF JC DEBOER AG MERKLE HP JUNGINGER HE
Citation: Hl. Luessen et al., MUCOADHESIVE POLYMERS IN PERORAL PEPTIDE DRUG-DELIVERY .5. EFFECT OF POLY(ACRYLATES) ON THE ENZYMATIC DEGRADATION OF PEPTIDE DRUGS BY INTESTINAL BRUSH-BORDER MEMBRANE-VESICLES, International journal of pharmaceutics, 141(1-2), 1996, pp. 39-52
ACUTE HISTOPATHOLOGICAL EFFECTS OF BENZALKONIUM CHLORIDE AND ABSORPTION ENHANCERS ON RAT NASAL EPITHELIUM IN-VIVO
Authors: MARTTIN E VERHOEF JC ROMEIJN SG ZWART P MERKUS FWHM
Citation: E. Marttin et al., ACUTE HISTOPATHOLOGICAL EFFECTS OF BENZALKONIUM CHLORIDE AND ABSORPTION ENHANCERS ON RAT NASAL EPITHELIUM IN-VIVO, International journal of pharmaceutics, 141(1-2), 1996, pp. 151-160
NOVEL PERORAL DOSAGE FORMS WITH PROTEASE INHIBITORY ACTIVITIES .2. DESIGN OF FAST DISSOLVING POLY(ACRYLATE) AND CONTROLLED DRUG-RELEASING CAPSULE FORMULATIONS WITH TRYPSIN INHIBITING PROPERTIES
Authors: AKIYAMA Y LUESSEN HL DEBOER AG VERHOEF JC JUNGINGER HE
Citation: Y. Akiyama et al., NOVEL PERORAL DOSAGE FORMS WITH PROTEASE INHIBITORY ACTIVITIES .2. DESIGN OF FAST DISSOLVING POLY(ACRYLATE) AND CONTROLLED DRUG-RELEASING CAPSULE FORMULATIONS WITH TRYPSIN INHIBITING PROPERTIES, International journal of pharmaceutics, 138(1), 1996, pp. 13-23
NOVEL PERORAL DOSAGE FORMS WITH PROTEASE INHIBITORY ACTIVITIES .1. DESIGN OF CAPSULES WITH FAST GEL-FORMING AND FAST DRUG-RELEASING PROPERTIES
Authors: AKIYAMA Y LUESSEN HL DEBOER AG VERHOEF JC JUNGINGER HE
Citation: Y. Akiyama et al., NOVEL PERORAL DOSAGE FORMS WITH PROTEASE INHIBITORY ACTIVITIES .1. DESIGN OF CAPSULES WITH FAST GEL-FORMING AND FAST DRUG-RELEASING PROPERTIES, International journal of pharmaceutics, 136(1-2), 1996, pp. 155-163
THE EFFECT OF NASAL DRUG FORMULATIONS ON CILIARY BEATING IN-VITRO
Authors: ROMEIJN SG VERHOEF JC MARTTIN E MERKUS FWHM
Citation: Sg. Romeijn et al., THE EFFECT OF NASAL DRUG FORMULATIONS ON CILIARY BEATING IN-VITRO, International journal of pharmaceutics, 135(1-2), 1996, pp. 137-145
5TH INTERNATIONAL-SYMPOSIUM ON DELIVERY AND TARGETING OF PEPTIDES, PROTEINS AND GENES LEIDEN, THE NETHERLANDS, 17-20 MAY 1995 - GUEST EDITORIAL
Authors: VERHOEF JC BREIMER DD
Citation: Jc. Verhoef et Dd. Breimer, 5TH INTERNATIONAL-SYMPOSIUM ON DELIVERY AND TARGETING OF PEPTIDES, PROTEINS AND GENES LEIDEN, THE NETHERLANDS, 17-20 MAY 1995 - GUEST EDITORIAL, Journal of controlled release, 41(1-2), 1996, pp. 1-1
THE INFLUENCE OF ABSORPTION ENHANCERS ON INTRANASAL INSULIN ABSORPTION IN NORMAL AND DIABETIC SUBJECTS
Authors: MERKUS FWHM SCHIPPER NGM VERHOEF JC
Citation: Fwhm. Merkus et al., THE INFLUENCE OF ABSORPTION ENHANCERS ON INTRANASAL INSULIN ABSORPTION IN NORMAL AND DIABETIC SUBJECTS, Journal of controlled release, 41(1-2), 1996, pp. 69-75
BUCCAL DELIVERY OF FLUORESCEIN ISOTHIOCYANATE-DEXTRAN-4400 AND THE PEPTIDE DRUG BUSERELIN WITH GLYCODEOXYCHOLATE AS AN ABSORPTION ENHANCER IN PIGS
Authors: HOOGSTRAATE AJ VERHOEF JC TUK B PIJPERS A VANLEENGOED LAMG VERHEIJDEN JHM JUNGINGER HE BODDE HE
Citation: Aj. Hoogstraate et al., BUCCAL DELIVERY OF FLUORESCEIN ISOTHIOCYANATE-DEXTRAN-4400 AND THE PEPTIDE DRUG BUSERELIN WITH GLYCODEOXYCHOLATE AS AN ABSORPTION ENHANCER IN PIGS, Journal of controlled release, 41(1-2), 1996, pp. 77-84
THE POTENTIAL OF MUCOADHESIVE POLYMERS IN ENHANCING INTESTINAL PEPTIDE DRUG ABSORPTION .3. EFFECTS OF CHITOSAN-GLUTAMATE AND CARBOMER ON EPITHELIAL TIGHT JUNCTIONS IN-VITRO
Authors: BORCHARD G LUESSEN HL DEBOER AG VERHOEF JC LEHR CM JUNGINGER HE
Citation: G. Borchard et al., THE POTENTIAL OF MUCOADHESIVE POLYMERS IN ENHANCING INTESTINAL PEPTIDE DRUG ABSORPTION .3. EFFECTS OF CHITOSAN-GLUTAMATE AND CARBOMER ON EPITHELIAL TIGHT JUNCTIONS IN-VITRO, Journal of controlled release, 39(2-3), 1996, pp. 131-138
IN-VIVO BUCCAL DELIVERY OF FLUORESCEIN-ISOTHIOCYANATE DEXTRAN-4400 WITH GLYCODEOXYCHOLATE AS AN ABSORPTION ENHANCER IN PIGS
Authors: HOOGSTRAATE AJ VERHOEF JC TUK B PIJPERS A VANLEENGOED LAMG VERHEIJDEN JHM JUNGINGER HE BODDE HE
Citation: Aj. Hoogstraate et al., IN-VIVO BUCCAL DELIVERY OF FLUORESCEIN-ISOTHIOCYANATE DEXTRAN-4400 WITH GLYCODEOXYCHOLATE AS AN ABSORPTION ENHANCER IN PIGS, Journal of pharmaceutical sciences, 85(5), 1996, pp. 457-460
Risultati: 1-25 | 26-42