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Results: 1-9 |
Results: 9
CHARACTERIZATION OF THE HYDROLYTIC ACTIVITY OF A POLYCLONAL CATALYTICANTIBODY PREPARATION BY PH-DEPENDENCE AND CHEMICAL MODIFICATION STUDIES - EVIDENCE FOR THE INVOLVEMENT OF TYR AND ARG SIDE-CHAINS AS HYDROGEN-BOND DONORS
Authors: RESMINI M VIGNA R SIMMS C BARBER NJ HAGIPAVLI EP WATTS AB VERMA C GALLACHER G BROCKLEHURST K
Citation: M. Resmini et al., CHARACTERIZATION OF THE HYDROLYTIC ACTIVITY OF A POLYCLONAL CATALYTICANTIBODY PREPARATION BY PH-DEPENDENCE AND CHEMICAL MODIFICATION STUDIES - EVIDENCE FOR THE INVOLVEMENT OF TYR AND ARG SIDE-CHAINS AS HYDROGEN-BOND DONORS, Biochemical journal, 326, 1997, pp. 279-287
A CLASSICAL ENZYME ACTIVE-CENTER MOTIF LACKS CATALYTIC COMPETENCE UNTIL MODULATED ELECTROSTATICALLY
Authors: PINITGLANG S WATTS AB PATEL M REID JD NOBLE MA GUL S BOKTH A NAEEM A PATEL H THOMAS EW SREEDHARAN SK VERMA C BROCKLEHURST K
Citation: S. Pinitglang et al., A CLASSICAL ENZYME ACTIVE-CENTER MOTIF LACKS CATALYTIC COMPETENCE UNTIL MODULATED ELECTROSTATICALLY, Biochemistry, 36(33), 1997, pp. 9968-9982
STUDIES ON THE ENHANCEMENT OF THE REACTIVITY OF THE (CYS-25)-S- (HIS159)-IM(+)H ION-PAIR OF PAPAIN BY DEPROTONATION ACROSS PK(A)4/
Authors: PINITGLANG S NOBLE M VERMA C THOMAS EW BROCKLEHURST K
Citation: S. Pinitglang et al., STUDIES ON THE ENHANCEMENT OF THE REACTIVITY OF THE (CYS-25)-S- (HIS159)-IM(+)H ION-PAIR OF PAPAIN BY DEPROTONATION ACROSS PK(A)4/, Biochemical Society transactions, 24(3), 1996, pp. 468-468
INVESTIGATION OF ELECTROSTATIC INTERACTIONS AND BINDING EFFECTS IN PAPIN-LIGAND INTERACTION
Authors: GUL S DHILLON PS VERMA C THOMAS EW BROCKLEHURST K
Citation: S. Gul et al., INVESTIGATION OF ELECTROSTATIC INTERACTIONS AND BINDING EFFECTS IN PAPIN-LIGAND INTERACTION, Biochemical Society transactions, 24(3), 1996, pp. 473-473
ENGINEERING THE C-REGION OF HUMAN INSULIN-LIKE GROWTH-FACTOR-I - IMPLICATIONS FOR RECEPTOR-BINDING
Authors: GILL R WALLACH B VERMA C URSO B DEWOLF E GROTZINGER J MURRAYRUST J PITTS J WOLLMER A DEMEYTS P WOOD S
Citation: R. Gill et al., ENGINEERING THE C-REGION OF HUMAN INSULIN-LIKE GROWTH-FACTOR-I - IMPLICATIONS FOR RECEPTOR-BINDING, Protein engineering, 9(11), 1996, pp. 1011-1019
DEMONSTRATION THAT NS-EPOXYSUCCINYL-L-LEUCYLAMIDO-(4-GUANIDINO)BUTANE(E-64) IS ONE OF THE MOST EFFECTIVE LOW M(R) INHIBITORS OF TRYPSIN-CATALYZED HYDROLYSIS. CHARACTERIZATION BY KINETIC-ANALYSIS AND BY ENERGYMINIMIZATION AND MOLECULAR-DYNAMICS SIMULATION OF THE E-64-BETA-TRYPSIN COMPLEX
Authors: SREEDHARAN SK VERMA C CAVES LSD BROCKLEHURST SM GHARBIA SE SHAH HN BROCKLEHURST K
Citation: Sk. Sreedharan et al., DEMONSTRATION THAT NS-EPOXYSUCCINYL-L-LEUCYLAMIDO-(4-GUANIDINO)BUTANE(E-64) IS ONE OF THE MOST EFFECTIVE LOW M(R) INHIBITORS OF TRYPSIN-CATALYZED HYDROLYSIS. CHARACTERIZATION BY KINETIC-ANALYSIS AND BY ENERGYMINIMIZATION AND MOLECULAR-DYNAMICS SIMULATION OF THE E-64-BETA-TRYPSIN COMPLEX, Biochemical journal, 316, 1996, pp. 777-786
CHARACTERIZATION OF THE ELECTROSTATIC PERTURBATION OF A CATALYTIC SITE (CYS)-S- (HIS)-IM(+)H ION-PAIR IN ONE TYPE OF SERINE PROTEINASE ARCHITECTURE BY KINETIC AND COMPUTATIONAL STUDIES ON CHEMICALLY MUTATED SUBTILISIN VARIANTS/
Authors: PLOU FJ KOWLESSUR D MALTHOUSE JPG MELLOR GW HARTSHORN MJ PINITGLANG S PATEL H TOPHAM CM THOMAS EW VERMA C BROCKLEHURST K
Citation: Fj. Plou et al., CHARACTERIZATION OF THE ELECTROSTATIC PERTURBATION OF A CATALYTIC SITE (CYS)-S- (HIS)-IM(+)H ION-PAIR IN ONE TYPE OF SERINE PROTEINASE ARCHITECTURE BY KINETIC AND COMPUTATIONAL STUDIES ON CHEMICALLY MUTATED SUBTILISIN VARIANTS/, Journal of Molecular Biology, 257(5), 1996, pp. 1088-1111
THE STRUCTURAL ORIGINS OF THE UNUSUAL SPECIFICITIES OBSERVED IN THE ISOLATION OF CHYMOPAPAIN-M AND ACTINIDIN BY COVALENT CHROMATOGRAPHY ANDTHE LACK OF INHIBITION OF CHYMOPAPAIN-M BY CYSTATIN
Authors: THOMAS MP VERMA C BOYD SM BROCKLEHURST K
Citation: Mp. Thomas et al., THE STRUCTURAL ORIGINS OF THE UNUSUAL SPECIFICITIES OBSERVED IN THE ISOLATION OF CHYMOPAPAIN-M AND ACTINIDIN BY COVALENT CHROMATOGRAPHY ANDTHE LACK OF INHIBITION OF CHYMOPAPAIN-M BY CYSTATIN, Biochemical journal, 306, 1995, pp. 39-46
PROBING THE NATURE OF SUBSTRATE-BINDING IN HUMICOLA-LANUGINOSA LIPASETHROUGH X-RAY CRYSTALLOGRAPHY AND INTUITIVE MODELING
Authors: LAWSON DM BRZOZOWSKI AM RETY S VERMA C DODSON GG
Citation: Dm. Lawson et al., PROBING THE NATURE OF SUBSTRATE-BINDING IN HUMICOLA-LANUGINOSA LIPASETHROUGH X-RAY CRYSTALLOGRAPHY AND INTUITIVE MODELING, Protein engineering, 7(4), 1994, pp. 543-550
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