Authors:
Rosowsky, A
Wright, JE
Vaidya, CM
Forsch, RA
Citation: A. Rosowsky et al., The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine, PHARM THERA, 85(3), 2000, pp. 191-205
Authors:
Rosowsky, A
Wright, JE
Vaidya, CM
Forsch, RA
Bader, H
Citation: A. Rosowsky et al., Analogues of the potent nonpolyglutamatable antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine (PT523) with modifications in the side chain, p-aminobenzoyl moiety, or 9,10-bridge: Synthesis and in vitro antitumor activity, J MED CHEM, 43(8), 2000, pp. 1620-1634
Authors:
Wright, JE
Vaidya, CM
Chen, YN
Rosowsky, A
Citation: Je. Wright et al., Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine (PT523) and its B-ring analogues, BIOCH PHARM, 60(1), 2000, pp. 41-46
Authors:
Rosowsky, A
Wright, JE
Vaidya, CM
Bader, H
Forsch, RA
Mota, CE
Pardo, J
Chen, CS
Chen, YN
Citation: A. Rosowsky et al., Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine (PT523), J MED CHEM, 41(26), 1998, pp. 5310-5319