Authors:
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Maas, HJ
Treijtel, N
Hulshof, J
Van der Graaf, PH
Peletier, LA
Danhof, M
Citation: Kp. Zuideveld et al., A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia, AM J P-REG, 281(6), 2001, pp. R2059-R2071
Authors:
Zuideveld, KP
Treijtel, N
Van der Graaf, PH
Danhof, M
Citation: Kp. Zuideveld et al., Enantioselective high-performance liquid chromatographic analysis of the 5-HT1A receptor agonist 8-hydroxy-2(di-n-propylamino)tetralin - Application to a pharmacokinetic-pharmacodynamic study in rats, J CHROMAT B, 738(1), 2000, pp. 67-73
Authors:
Cleton, A
Odman, J
Van der Graaf, PH
Ghijsen, W
Voskuyl, R
Danhof, M
Citation: A. Cleton et al., Mechanism-based modeling of functional adaptation upon chronic treatment with midazolam, PHARM RES, 17(3), 2000, pp. 321-327
Citation: Ph. Van Der Graaf et Wb. Stam, Analysis of receptor inactivation experiments with the operational model of agonism yields correlated estimates of agonist affinity and efficacy, J PHARM TOX, 41(2-3), 1999, pp. 117-125
Authors:
Cleton, A
Van der Graaf, PH
Ghijsen, W
Voskuyl, R
Danhof, M
Citation: A. Cleton et al., Mechanism-based modeling of adaptive changes in the pharmacodynamics of midazolam in the kindling model of epilepsy, PHARM RES, 16(11), 1999, pp. 1702-1709
Authors:
Van der Graaf, PH
Van Schaick, EA
Visser, SAG
De Greef, HJMM
Ijzerman, AP
Danhof, M
Citation: Ph. Van Der Graaf et al., Mechanism-based pharmacokinetic-pharmacodynamic modeling of antilipolytic effects of adenosine A(1) receptor agonists in rats: Prediction of tissue-dependent efficacy in vivo, J PHARM EXP, 290(2), 1999, pp. 702-709
Authors:
Van der Graaf, PH
Nilsson, J
Van Schaick, EA
Danhof, M
Citation: Ph. Van Der Graaf et al., Multivariate quantitative structure-pharmacokinetic relationships (QSPKR) analysis of adenosine A(1) receptor agonists in rat, J PHARM SCI, 88(3), 1999, pp. 306-312
Citation: Ph. Van Der Graaf, Estimation of agonist affinity, using the slope of the concentration-effect curve: Comment on the method of Calderone and Martinotti, J PHARM TOX, 40(4), 1998, pp. 241-243
Citation: Wb. Stam et al., Functional characterisation of the pharmacological profile of the putativealpha(1B)-adrenoceptor antagonist, (+)-cyclazosin, EUR J PHARM, 361(1), 1998, pp. 79-83