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Showalter, HDH
Zhou, HR
Bridges, AJ
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Fry, DW
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Sherwood, V
Vincent, PW
Roberts, BJ
Elliott, WL
Denny, WA
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 18. 6-substituted 4-anilinoquinazolines and 4-anilinopyrido [3,4-d]pyrimidines as soluble, irreversible inhibitors of theepidermal growth factor receptor, J MED CHEM, 44(3), 2001, pp. 429-440
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Schroeder, MC
Hamby, JM
Connolly, CJC
Grohar, PJ
Winters, RT
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Kraker, AJ
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Vincent, PW
Elliott, WL
Lu, GH
Batley, BL
Dahring, TK
Major, TC
Panek, RL
Doherty, AM
Showalter, HDH
Citation: Mc. Schroeder et al., Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity, J MED CHEM, 44(12), 2001, pp. 1915-1926
Authors:
Vincent, PW
Bridges, AJ
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Fry, DW
Leopold, WR
Patmore, SJ
Roberts, BJ
Rose, S
Sherwood, V
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Elliott, WL
Citation: Pw. Vincent et al., Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts, CANC CHEMOT, 45(3), 2000, pp. 231-238
Authors:
Thompson, AM
Connolly, CJC
Hamby, JM
Boushelle, S
Hartl, BG
Amar, AM
Kraker, AJ
Driscoll, DL
Steinkampf, RW
Patmore, SJ
Vincent, PW
Roberts, BJ
Elliott, WL
Klohs, W
Leopold, WR
Showalter, HDH
Denny, WA
Citation: Am. Thompson et al., 3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase, J MED CHEM, 43(22), 2000, pp. 4200-4211
Authors:
Smaill, JB
Rewcastle, GW
Bridges, AJ
Zhou, HR
Showalter, HDH
Fry, DW
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Sherwood, V
Elliott, WL
Vincent, PW
DeJohn, DE
Loo, JA
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Chan, OH
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Lipka, E
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Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]-pyrimidine-6-acrylamides bearing additional solubilizing functions(vol 43, pg 1380, 2000), J MED CHEM, 43(16), 2000, pp. 3199-3199
Authors:
Smaill, JB
Palmer, BD
Rewcastle, GW
Denny, WA
McNamara, DJ
Dobrusin, EM
Bridges, AJ
Zhou, HR
Showalter, HDH
Winters, RT
Leopold, WR
Fry, DW
Nelson, JM
Slintak, V
Elliot, WL
Roberts, BJ
Vincent, PW
Patmore, SJ
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 15. 4-(phenylamino)quinazoline and 4-(phenylamino)pyrido[d] pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor, J MED CHEM, 42(10), 1999, pp. 1803-1815