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Results: 1-25/137
HOMOLOGS OF THE VANCOMYCIN RESISTANCE D-ALA-D-ALA DIPEPTIDASE VANX INSTREPTOMYCES-TOYOCAENSIS, ESCHERICHIA-COLI AND SYNECHOCYSTIS - ATTRIBUTES OF CATALYTIC EFFICIENCY, STEREOSELECTIVITY AND REGULATION WITH IMPLICATIONS FOR FUNCTION
Authors: LESSARD IAD PRATT SD MCCAFFERTY DG BUSSIERE DE HUTCHINS C WANNER BL KATZ L WALSH CT
Citation: Iad. Lessard et al., HOMOLOGS OF THE VANCOMYCIN RESISTANCE D-ALA-D-ALA DIPEPTIDASE VANX INSTREPTOMYCES-TOYOCAENSIS, ESCHERICHIA-COLI AND SYNECHOCYSTIS - ATTRIBUTES OF CATALYTIC EFFICIENCY, STEREOSELECTIVITY AND REGULATION WITH IMPLICATIONS FOR FUNCTION, Chemistry & biology, 5(9), 1998, pp. 489-504
KINETICS AND REGIOSELECTIVITY OF PEPTIDE-TO-HETEROCYCLE CONVERSIONS BY MICROCIN B17 SYNTHETASE
Authors: BELSHAW PJ ROY RS KELLEHER NL WALSH CT
Citation: Pj. Belshaw et al., KINETICS AND REGIOSELECTIVITY OF PEPTIDE-TO-HETEROCYCLE CONVERSIONS BY MICROCIN B17 SYNTHETASE, Chemistry & biology, 5(7), 1998, pp. 373-384
ACTIVE-SITE MUTANTS OF THE VANC2 D-ALANYL-D-SERINE LIGASE, CHARACTERISTIC OF ONE VANCOMYCIN-RESISTANT BACTERIAL PHENOTYPE, REVERT TOWARDS WILD-TYPE D-ALANYL-D-ALANINE LIGASES
Authors: HEALY VL PARK IS WALSH CT
Citation: Vl. Healy et al., ACTIVE-SITE MUTANTS OF THE VANC2 D-ALANYL-D-SERINE LIGASE, CHARACTERISTIC OF ONE VANCOMYCIN-RESISTANT BACTERIAL PHENOTYPE, REVERT TOWARDS WILD-TYPE D-ALANYL-D-ALANINE LIGASES, Chemistry & biology, 5(4), 1998, pp. 197-207
ROLE OF THE MICROCIN B17 PROPEPTIDE IN SUBSTRATE RECOGNITION - SOLUTION STRUCTURE AND MUTATIONAL ANALYSIS OF MCBA(1-26)
Authors: ROY RS KIM S BALEJA JD WALSH CT
Citation: Rs. Roy et al., ROLE OF THE MICROCIN B17 PROPEPTIDE IN SUBSTRATE RECOGNITION - SOLUTION STRUCTURE AND MUTATIONAL ANALYSIS OF MCBA(1-26), Chemistry & biology, 5(4), 1998, pp. 217-228
IDENTIFICATION OF A MYCOBACTERIUM-TUBERCULOSIS GENE-CLUSTER ENCODING THE BIOSYNTHETIC-ENZYMES FOR ASSEMBLY OF THE VIRULENCE-CONFERRING SIDEROPHORE MYCOBACTIN
Authors: QUADRI LEN SELLO J KEATING TA WEINREB PH WALSH CT
Citation: Len. Quadri et al., IDENTIFICATION OF A MYCOBACTERIUM-TUBERCULOSIS GENE-CLUSTER ENCODING THE BIOSYNTHETIC-ENZYMES FOR ASSEMBLY OF THE VIRULENCE-CONFERRING SIDEROPHORE MYCOBACTIN, Chemistry & biology, 5(11), 1998, pp. 631-645
IRON ACQUISITION IN PLAGUE - MODULAR LOGIC IN ENZYMATIC BIOGENESIS OFYERSINIABACTIN BY YERSINIA-PESTIS
Authors: GEHRING AM DEMOLL E FETHERSTON JD MORI I MAYHEW GF BLATTNER FR WALSH CT PERRY RD
Citation: Am. Gehring et al., IRON ACQUISITION IN PLAGUE - MODULAR LOGIC IN ENZYMATIC BIOGENESIS OFYERSINIABACTIN BY YERSINIA-PESTIS, Chemistry & biology, 5(10), 1998, pp. 573-586
BIOCHEMISTRY - HARNESSING THE BIOSYNTHETIC CODE - COMBINATIONS, PERMUTATIONS, AND MUTATIONS
Authors: CANE DE WALSH CT KHOSLA C
Citation: De. Cane et al., BIOCHEMISTRY - HARNESSING THE BIOSYNTHETIC CODE - COMBINATIONS, PERMUTATIONS, AND MUTATIONS, Science, 282(5386), 1998, pp. 63-68
IN-VIVO CHARACTERIZATION OF THE TYPE-A AND TYPE-B VANCOMYCIN-RESISTANT ENTEROCOCCI (VRE) VANRS 2-COMPONENT SYSTEMS IN ESCHERICHIA-COLI - A NONPATHOGENIC MODEL FOR STUDYING THE VRE SIGNAL-TRANSDUCTION PATHWAYS
Authors: SILVA JC HALDIMANN A PRAHALAD MK WALSH CT WANNER BL
Citation: Jc. Silva et al., IN-VIVO CHARACTERIZATION OF THE TYPE-A AND TYPE-B VANCOMYCIN-RESISTANT ENTEROCOCCI (VRE) VANRS 2-COMPONENT SYSTEMS IN ESCHERICHIA-COLI - A NONPATHOGENIC MODEL FOR STUDYING THE VRE SIGNAL-TRANSDUCTION PATHWAYS, Proceedings of the National Academy of Sciences of the United Statesof America, 95(20), 1998, pp. 11951-11956
FUNCTIONAL-ANALYSIS OF AN INTERSPECIES CHIMERA OF ACYL CARRIER PROTEINS INDICATES A SPECIALIZED DOMAIN FOR PROTEIN RECOGNITION
Authors: RITSEMA T GEHRING AM STUITJE AR VANDERDRIFT KMGM DANDAL I LAMBALOT RH WALSH CT THOMASOATES JE LUGTENBERG BJJ SPAINK HP
Citation: T. Ritsema et al., FUNCTIONAL-ANALYSIS OF AN INTERSPECIES CHIMERA OF ACYL CARRIER PROTEINS INDICATES A SPECIALIZED DOMAIN FOR PROTEIN RECOGNITION, MGG. Molecular & general genetics, 257(6), 1998, pp. 641-648
CLONING AND CHARACTERIZATION OF THE 2 ENZYMES RESPONSIBLE FOR TRYPANOTHIONE BIOSYNTHESIS IN CRITHIDIA-FASCICULATA
Authors: TETAUD E MANAI F BARRETT MP NADEAU K WALSH CT FAIRLAMB AH
Citation: E. Tetaud et al., CLONING AND CHARACTERIZATION OF THE 2 ENZYMES RESPONSIBLE FOR TRYPANOTHIONE BIOSYNTHESIS IN CRITHIDIA-FASCICULATA, The Journal of biological chemistry, 273(31), 1998, pp. 19383-19390
STEREOCHEMICAL COURSE OF ENZYMATIC ENOLPYRUVYL TRANSFER AND CATALYTICCONFORMATION OF THE ACTIVE-SITE REVEALED BY THE CRYSTAL-STRUCTURE OF THE FLUORINATED ANALOG OF THE REACTION TETRAHEDRAL INTERMEDIATE BOUND TO THE ACTIVE-SITE OF THE C115A MUTANT OF MURA
Authors: SKARZYNSKI T KIM DH LEES WJ WALSH CT DUNCAN K
Citation: T. Skarzynski et al., STEREOCHEMICAL COURSE OF ENZYMATIC ENOLPYRUVYL TRANSFER AND CATALYTICCONFORMATION OF THE ACTIVE-SITE REVEALED BY THE CRYSTAL-STRUCTURE OF THE FLUORINATED ANALOG OF THE REACTION TETRAHEDRAL INTERMEDIATE BOUND TO THE ACTIVE-SITE OF THE C115A MUTANT OF MURA, Biochemistry, 37(8), 1998, pp. 2572-2577
RECONSTITUTION AND CHARACTERIZATION OF THE ESCHERICHIA-COLI ENTEROBACTIN SYNTHETASE FROM ENTB, ENTE, AND ENTF
Authors: GEHRING AM MORI I WALSH CT
Citation: Am. Gehring et al., RECONSTITUTION AND CHARACTERIZATION OF THE ESCHERICHIA-COLI ENTEROBACTIN SYNTHETASE FROM ENTB, ENTE, AND ENTF, Biochemistry, 37(8), 1998, pp. 2648-2659
STOICHIOMETRY AND SPECIFICITY OF IN-VITRO PHOSPHOPANTETHEINYLATION AND AMINOACYLATION OF THE VALINE-ACTIVATING MODULE OF SURFACTIN SYNTHETASE
Authors: WEINREB PH QUADRI LEN WALSH CT ZUBER P
Citation: Ph. Weinreb et al., STOICHIOMETRY AND SPECIFICITY OF IN-VITRO PHOSPHOPANTETHEINYLATION AND AMINOACYLATION OF THE VALINE-ACTIVATING MODULE OF SURFACTIN SYNTHETASE, Biochemistry, 37(6), 1998, pp. 1575-1584
CHARACTERIZATION OF SFP, A BACILLUS-SUBTILIS PHOSPHOPANTETHEINYL TRANSFERASE FOR PEPTIDYL CARRIER PROTEIN DOMAINS IN PEPTIDE SYNTHETASES
Authors: QUADRI LEN WEINREB PH LEI M NAKANO MM ZUBER P WALSH CT
Citation: Len. Quadri et al., CHARACTERIZATION OF SFP, A BACILLUS-SUBTILIS PHOSPHOPANTETHEINYL TRANSFERASE FOR PEPTIDYL CARRIER PROTEIN DOMAINS IN PEPTIDE SYNTHETASES, Biochemistry, 37(6), 1998, pp. 1585-1595
ATP GTP HYDROLYSIS IS REQUIRED FOR OXAZOLE AND THIAZOLE BIOSYNTHESIS IN THE PEPTIDE ANTIBIOTIC MICROCIN B17/
Authors: MILNE JC ELIOT AC KELLEHER NL WALSH CT
Citation: Jc. Milne et al., ATP GTP HYDROLYSIS IS REQUIRED FOR OXAZOLE AND THIAZOLE BIOSYNTHESIS IN THE PEPTIDE ANTIBIOTIC MICROCIN B17/, Biochemistry, 37(38), 1998, pp. 13250-13261
THE NONRIBOSOMAL PEPTIDE SYNTHETASE HMWP2 FORMS A THIAZOLINE RING DURING BIOGENESIS OF YERSINIABACTIN, AN IRON-CHELATING VIRULENCE FACTOR OF YERSINIA-PESTIS
Authors: GEHRING AM MORI I PERRY RD WALSH CT
Citation: Am. Gehring et al., THE NONRIBOSOMAL PEPTIDE SYNTHETASE HMWP2 FORMS A THIAZOLINE RING DURING BIOGENESIS OF YERSINIABACTIN, AN IRON-CHELATING VIRULENCE FACTOR OF YERSINIA-PESTIS, Biochemistry, 37(33), 1998, pp. 11637-11650
MUTATIONAL ANALYSIS OF POSTTRANSLATIONAL HETEROCYCLE BIOSYNTHESIS IN THE GYRASE INHIBITOR MICROCIN B17 - DISTANCE DEPENDENCE FROM PROPEPTIDE AND TOLERANCE FOR SUBSTITUTION IN A GSCG CYCLIZABLE SEQUENCE
Authors: ROY RS BELSHAW PJ WALSH CT
Citation: Rs. Roy et al., MUTATIONAL ANALYSIS OF POSTTRANSLATIONAL HETEROCYCLE BIOSYNTHESIS IN THE GYRASE INHIBITOR MICROCIN B17 - DISTANCE DEPENDENCE FROM PROPEPTIDE AND TOLERANCE FOR SUBSTITUTION IN A GSCG CYCLIZABLE SEQUENCE, Biochemistry, 37(12), 1998, pp. 4125-4136
REGIOSELECTIVITY AND CHEMOSELECTIVITY ANALYSIS OF OXAZOLE AND THIAZOLE RING FORMATION BY THE PEPTIDE-HETEROCYCLIZING MICROCIN B17 SYNTHETASE USING HIGH-RESOLUTION MS MS/
Authors: KELLEHER NL BELSHAW PJ WALSH CT
Citation: Nl. Kelleher et al., REGIOSELECTIVITY AND CHEMOSELECTIVITY ANALYSIS OF OXAZOLE AND THIAZOLE RING FORMATION BY THE PEPTIDE-HETEROCYCLIZING MICROCIN B17 SYNTHETASE USING HIGH-RESOLUTION MS MS/, Journal of the American Chemical Society, 120(37), 1998, pp. 9716-9717
MECHANISMS RESEARCH HIGHLIGHTS AT THE CHEMISTRY BIOLOGY INTERFACE - EDITORIAL OVERVIEW/
Authors: BENKOVIC SJ WALSH CT
Citation: Sj. Benkovic et Ct. Walsh, MECHANISMS RESEARCH HIGHLIGHTS AT THE CHEMISTRY BIOLOGY INTERFACE - EDITORIAL OVERVIEW/, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(3), 1997, pp. 289-291
POSTTRANSLATIONAL MODIFICATION OF POLYKETIDE AND NONRIBOSOMAL PEPTIDESYNTHASES
Authors: WALSH CT GEHRING AM WEINREB PH QUADRI LEN FLUGEL RS
Citation: Ct. Walsh et al., POSTTRANSLATIONAL MODIFICATION OF POLYKETIDE AND NONRIBOSOMAL PEPTIDESYNTHASES, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(3), 1997, pp. 309-315
ALDEHYDE AND PHOSPHINATE ANALOGS OF GLUTATHIONE AND GLUTATHIONYLSPERMIDINE - POTENT, SELECTIVE BINDING INHIBITORS OF THE ESCHERICHIA-COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE AMIDASE/
Authors: LIN CH CHEN SJ KWON DS COWARD JK WALSH CT
Citation: Ch. Lin et al., ALDEHYDE AND PHOSPHINATE ANALOGS OF GLUTATHIONE AND GLUTATHIONYLSPERMIDINE - POTENT, SELECTIVE BINDING INHIBITORS OF THE ESCHERICHIA-COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE AMIDASE/, Chemistry & biology, 4(11), 1997, pp. 859-866
ABILITY OF STREPTOMYCES SPP ACYL CARRIER PROTEINS AND COENZYME-A ANALOGS TO SERVE AS SUBSTRATES IN-VITRO FOR ESCHERICHIA-COLI HOLO-ACP SYNTHASE
Authors: GEHRING AM LAMBALOT RH VOGEL KW DRUECKHAMMER DG WALSH CT
Citation: Am. Gehring et al., ABILITY OF STREPTOMYCES SPP ACYL CARRIER PROTEINS AND COENZYME-A ANALOGS TO SERVE AS SUBSTRATES IN-VITRO FOR ESCHERICHIA-COLI HOLO-ACP SYNTHASE, Chemistry & biology, 4(1), 1997, pp. 17-24
MECHANISMS OF BACTERIAL-RESISTANCE TO VANCOMYCIN
Authors: GREEN TB SILVA J PRAHALAD M WALSH CT
Citation: Tb. Green et al., MECHANISMS OF BACTERIAL-RESISTANCE TO VANCOMYCIN, Molecular biology of the cell, 8, 1997, pp. 683-683
NOVEL INHIBITORS OF TRYPANOTHIONE BIOSYNTHESIS - SYNTHESIS AND EVALUATION OF A PHOSPHINATE ANALOG OF GLUTATHIONYL SPERMIDINE (GSP), A POTENT, SLOW-BINDING INHIBITOR OF GSP SYNTHETASE
Authors: CHEN SJ LIN CH WALSH CT COWARD JK
Citation: Sj. Chen et al., NOVEL INHIBITORS OF TRYPANOTHIONE BIOSYNTHESIS - SYNTHESIS AND EVALUATION OF A PHOSPHINATE ANALOG OF GLUTATHIONYL SPERMIDINE (GSP), A POTENT, SLOW-BINDING INHIBITOR OF GSP SYNTHETASE, Bioorganic & medicinal chemistry letters, 7(5), 1997, pp. 505-510
NOVEL INHIBITORS OF TRYPANOTHIONE BIOSYNTHESIS - SYNTHESIS AND EVALUATION OF A PHOSPHINATE ANALOG OF GLUTATHIONYL SPERMIDINE (GSP), A POTENT, SLOW-BINDING INHIBITOR OF GSP SYNTHETASE (VOL 7, PG 505, 1997)
Authors: CHEN S LIN CH WALSH CT COWARD JK
Citation: S. Chen et al., NOVEL INHIBITORS OF TRYPANOTHIONE BIOSYNTHESIS - SYNTHESIS AND EVALUATION OF A PHOSPHINATE ANALOG OF GLUTATHIONYL SPERMIDINE (GSP), A POTENT, SLOW-BINDING INHIBITOR OF GSP SYNTHETASE (VOL 7, PG 505, 1997), Bioorganic & medicinal chemistry letters, 7(19), 1997, pp. 2557-2557
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