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Results: 1-25 | 26-35
Results: 1-25/35
TARGETED GENE KNOCKOUT MEDIATED BY TRIPLE-HELIX FORMING OLIGONUCLEOTIDES
Authors: MAJUMDAR A KHORLIN A DYATKINA N LIN FLM POWELL J LIU J FEIZ ZZ KHRIPINE Y WATANABE KA GEORGE J GLAZER PM SEIDMAN MM
Citation: A. Majumdar et al., TARGETED GENE KNOCKOUT MEDIATED BY TRIPLE-HELIX FORMING OLIGONUCLEOTIDES, Nature genetics, 20(2), 1998, pp. 212-214
SYNTHESIS OF 2'-DEOXYNUCLEOSIDE 5'-METHYLENEBIS-(PHOSPHONATE)S USING 2-(4-NITROPHENYL)ETHYL METHYLENE-BIS(PHOSPHONATE) AS THE PHOSPHONYLATING AGENT
Authors: LESIAK K WATANABE KA PANKIEWICZ KW
Citation: K. Lesiak et al., SYNTHESIS OF 2'-DEOXYNUCLEOSIDE 5'-METHYLENEBIS-(PHOSPHONATE)S USING 2-(4-NITROPHENYL)ETHYL METHYLENE-BIS(PHOSPHONATE) AS THE PHOSPHONYLATING AGENT, Nucleosides & nucleotides, 17(9-11), 1998, pp. 1857-1860
THE PARALLEL AND ANTIPARALLEL TRIPLEX FORMATION AND STABILITY OF SELF-COMPLEMENTARY OLIGONUCLEOTIDES CONTAINING 2'-FLUORO-ARABINOSYL THYMINE AND 5-METHYL-2'-DEOXYCYTIDINE
Authors: REN WY WATANABE KA
Citation: Wy. Ren et Ka. Watanabe, THE PARALLEL AND ANTIPARALLEL TRIPLEX FORMATION AND STABILITY OF SELF-COMPLEMENTARY OLIGONUCLEOTIDES CONTAINING 2'-FLUORO-ARABINOSYL THYMINE AND 5-METHYL-2'-DEOXYCYTIDINE, Nucleosides & nucleotides, 17(9-11), 1998, pp. 2103-2116
SUBSTRATES OF DNA-POLYMERASES WITH PLANAR CONFORMATION OF SUGAR - MODEL OF SUBSTRATE TRANSITION-STATE
Authors: KRAYEVSKY AA WATANABE KA
Citation: Aa. Krayevsky et Ka. Watanabe, SUBSTRATES OF DNA-POLYMERASES WITH PLANAR CONFORMATION OF SUGAR - MODEL OF SUBSTRATE TRANSITION-STATE, Nucleosides & nucleotides, 17(7), 1998, pp. 1153-1162
2-(4-NITROPHENYL)ETHYL METHYLENEBIS(PHOSPHONATE) - A VERSATILE REAGENT FOR THE SYNTHESIS OF NUCLEOSIDE 5'-METHYLENEBIS(PHOSPHONATE)S
Authors: LESIAK K WATANABE KA GEORGE J PANKIEWICZ KW
Citation: K. Lesiak et al., 2-(4-NITROPHENYL)ETHYL METHYLENEBIS(PHOSPHONATE) - A VERSATILE REAGENT FOR THE SYNTHESIS OF NUCLEOSIDE 5'-METHYLENEBIS(PHOSPHONATE)S, Journal of organic chemistry, 63(6), 1998, pp. 1906-1909
DETERMINATION OF THE TAUTOMERIC EQUILIBRIUM OF PSI-URIDINE IN THE BASIC SOLUTION
Authors: LUYTEN I PANKIEWICZ KW WATANABE KA CHATTOPADHYAYA J
Citation: I. Luyten et al., DETERMINATION OF THE TAUTOMERIC EQUILIBRIUM OF PSI-URIDINE IN THE BASIC SOLUTION, Journal of organic chemistry, 63(4), 1998, pp. 1033-1040
SYNTHESIS OF A METHYLENEBIS(PHOSPHONATE) ANALOG OF MYCOPHENOLIC ADENINE-DINUCLEOTIDE - A GLUCURONIDATION-RESISTANT MAD ANALOG OF NAD
Authors: LESIAK K WATANABE KA MAJUMDAR A POWELL J SEIDMAN M VANDERVEEN K GOLDSTEIN BM PANKIEWICZ KW
Citation: K. Lesiak et al., SYNTHESIS OF A METHYLENEBIS(PHOSPHONATE) ANALOG OF MYCOPHENOLIC ADENINE-DINUCLEOTIDE - A GLUCURONIDATION-RESISTANT MAD ANALOG OF NAD, Journal of medicinal chemistry, 41(4), 1998, pp. 618-622
ALIPHATIC AND ALICYCLIC DIOLS INDUCE MELANOGENESIS IN CULTURED-CELLS AND GUINEA-PIG SKIN
Authors: BROWN DA REN WY KHORLIN A LESIAK K CONKLIN D WATANABE KA SEIDMAN MM GEORGE J
Citation: Da. Brown et al., ALIPHATIC AND ALICYCLIC DIOLS INDUCE MELANOGENESIS IN CULTURED-CELLS AND GUINEA-PIG SKIN, Journal of investigative dermatology, 110(4), 1998, pp. 428-437
THE PRACTICAL SYNTHESIS OF A METHYLENEBISPHOSPHONATE ANALOG OF BENZAMIDE ADENINE-DINUCLEOTIDE - INHIBITION OF HUMAN INOSINE MONOPHOSPHATE DEHYDROGENASE (TYPE-I AND TYPE-II)
Authors: PANKIEWICZ KW LESIAK K ZATORSKI A GOLDSTEIN BM CARR SF SOCHACKI M MAJUMDAR A SEIDMAN M WATANABE KA
Citation: Kw. Pankiewicz et al., THE PRACTICAL SYNTHESIS OF A METHYLENEBISPHOSPHONATE ANALOG OF BENZAMIDE ADENINE-DINUCLEOTIDE - INHIBITION OF HUMAN INOSINE MONOPHOSPHATE DEHYDROGENASE (TYPE-I AND TYPE-II), Journal of medicinal chemistry, 40(8), 1997, pp. 1287-1291
SYNTHESIS OF NONHYDROLYZABLE ANALOGS OF THIAZOLE-4-CARBOXAMIDE AND BENZAMIDE ADENINE-DINUCLEOTIDE CONTAINING FLUORINE ATOM AT THE C2' OF ADENINE NUCLEOSIDE - INDUCTION OF K562 DIFFERENTIATION AND INOSINE MONOPHOSPHATE DEHYDROGENASE INHIBITORY ACTIVITY
Authors: LESIAK K WATANABE KA MAJUMDAR A SEIDMAN M VANDERVEEN K GOLDSTEIN BM PANKIEWICZ KW
Citation: K. Lesiak et al., SYNTHESIS OF NONHYDROLYZABLE ANALOGS OF THIAZOLE-4-CARBOXAMIDE AND BENZAMIDE ADENINE-DINUCLEOTIDE CONTAINING FLUORINE ATOM AT THE C2' OF ADENINE NUCLEOSIDE - INDUCTION OF K562 DIFFERENTIATION AND INOSINE MONOPHOSPHATE DEHYDROGENASE INHIBITORY ACTIVITY, Journal of medicinal chemistry, 40(16), 1997, pp. 2533-2538
EFFICIENT SYNTHESIS OF METHYLENEBIS(PHOSPHONATE) ANALOGS OF P-1,P-2-DISUBSTITUTED PYROPHOSPHATES OF BIOLOGICAL INTEREST - A NOVEL PLAUSIBLEMECHANISM
Authors: PANKIEWICZ KW LESIAK K WATANABE KA
Citation: Kw. Pankiewicz et al., EFFICIENT SYNTHESIS OF METHYLENEBIS(PHOSPHONATE) ANALOGS OF P-1,P-2-DISUBSTITUTED PYROPHOSPHATES OF BIOLOGICAL INTEREST - A NOVEL PLAUSIBLEMECHANISM, Journal of the American Chemical Society, 119(16), 1997, pp. 3691-3695
SPECIAL ISSUE IN HONOR OF DR MIZUNO,YOSHIHISA - PREFACE
Authors: WATANABE KA
Citation: Ka. Watanabe, SPECIAL ISSUE IN HONOR OF DR MIZUNO,YOSHIHISA - PREFACE, Nucleosides & nucleotides, 15(1-3), 1996, pp. 15-17
SYNTHESIS OF METHYLENE-BRIDGED ANALOGS OF NICOTINAMIDE RIBOSIDE, NICOTINAMIDE MONONUCLEOTIDE AND NICOTINAMIDE ADENINE-DINUCLEOTIDE
Authors: LIPKA P ZATORSKI A WATANABE KA PANKIEWICZ KW
Citation: P. Lipka et al., SYNTHESIS OF METHYLENE-BRIDGED ANALOGS OF NICOTINAMIDE RIBOSIDE, NICOTINAMIDE MONONUCLEOTIDE AND NICOTINAMIDE ADENINE-DINUCLEOTIDE, Nucleosides & nucleotides, 15(1-3), 1996, pp. 149-167
POLYDEOXYAMINOHEXOPYRANOSYLNUCLEOSIDES - SYNTHESIS OF EOXY-3-NITRO-BETA-D-ERYTHRO-HEXOPYRANOSYL)-URACILS AND IDEOXY-3-NITRO-BETA-D-THREO-HEXOPYRANOSYL)-URACILS FROM URIDINE
Authors: MATSUDA A WATANABE KA
Citation: A. Matsuda et Ka. Watanabe, POLYDEOXYAMINOHEXOPYRANOSYLNUCLEOSIDES - SYNTHESIS OF EOXY-3-NITRO-BETA-D-ERYTHRO-HEXOPYRANOSYL)-URACILS AND IDEOXY-3-NITRO-BETA-D-THREO-HEXOPYRANOSYL)-URACILS FROM URIDINE, Nucleosides & nucleotides, 15(1-3), 1996, pp. 205-217
FIALURIDINE AND ITS METABOLITES INHIBIT DNA-POLYMERASE-GAMMA AT SITESOF MULTIPLE ADJACENT ANALOG INCORPORATION, DECREASE MTDNA ABUNDANCE, AND CAUSE MITOCHONDRIAL STRUCTURAL DEFECTS IN CULTURED HEPATOBLASTS
Authors: LEWIS W LEVINE ES GRINIUVIENE B TANKERSLEY KO COLACINO JM SOMMADOSSI JP WATANABE KA PERRINO FW
Citation: W. Lewis et al., FIALURIDINE AND ITS METABOLITES INHIBIT DNA-POLYMERASE-GAMMA AT SITESOF MULTIPLE ADJACENT ANALOG INCORPORATION, DECREASE MTDNA ABUNDANCE, AND CAUSE MITOCHONDRIAL STRUCTURAL DEFECTS IN CULTURED HEPATOBLASTS, Proceedings of the National Academy of Sciences of the United Statesof America, 93(8), 1996, pp. 3592-3597
CYCLOPENT[A]ANTHRAQUINONES AS DNA-INTERCALATING AGENTS WITH COVALENT BOND FORMATION POTENTIAL - SYNTHESIS AND BIOLOGICAL-ACTIVITY
Authors: KIM JY SU TL CHOU TC KOEHLER B SCARBOROUGH A OUERFELLI O WATANABE KA
Citation: Jy. Kim et al., CYCLOPENT[A]ANTHRAQUINONES AS DNA-INTERCALATING AGENTS WITH COVALENT BOND FORMATION POTENTIAL - SYNTHESIS AND BIOLOGICAL-ACTIVITY, Journal of medicinal chemistry, 39(14), 1996, pp. 2812-2818
SYNTHESIS OF METHYLENEBIS(PHOSPHONATE) ANALOGS OF ADP-RIBOSE
Authors: PANKIEWICZ KW LESIAK K ZATORSKI A WATANABE KA
Citation: Kw. Pankiewicz et al., SYNTHESIS OF METHYLENEBIS(PHOSPHONATE) ANALOGS OF ADP-RIBOSE, Collection of Czechoslovak Chemical Communications, 61, 1996, pp. 92-95
NAD-ANALOGS AS POTENTIAL ANTICANCER AGENTS - CONFORMATIONAL RESTRICTIONS AS BASIS FOR SELECTIVITY
Authors: PANKIEWICZ KW ZATORSKI A WATANABE KA
Citation: Kw. Pankiewicz et al., NAD-ANALOGS AS POTENTIAL ANTICANCER AGENTS - CONFORMATIONAL RESTRICTIONS AS BASIS FOR SELECTIVITY, Acta Biochimica Polonica, 43(1), 1996, pp. 183-193
SYNTHESIS OF RO-5-[C-11]-METHYL-1-BETA-D-ARABINOFURANOSYLURACIL ([C-11]-FMAU) - A POTENTIAL NUCLEOSIDE ANALOG FOR IN-VIVO STUDY OF CELLULARPROLIFERATION WITH PET
Authors: CONTI PS ALAUDDIN MM FISSEKIS JR SCHMALL B WATANABE KA
Citation: Ps. Conti et al., SYNTHESIS OF RO-5-[C-11]-METHYL-1-BETA-D-ARABINOFURANOSYLURACIL ([C-11]-FMAU) - A POTENTIAL NUCLEOSIDE ANALOG FOR IN-VIVO STUDY OF CELLULARPROLIFERATION WITH PET, Nuclear medicine and biology, 22(6), 1995, pp. 783-789
9-SUBSTITUTED ACRIDINE-DERIVATIVES WITH LONG HALF-LIFE AND POTENT ANTITUMOR-ACTIVITY - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS
Authors: SU TL CHOU TC KIM JY HUANG JT CISZEWSKA G REN WY OTTER GM SIROTNAK FM WATANABE KA
Citation: Tl. Su et al., 9-SUBSTITUTED ACRIDINE-DERIVATIVES WITH LONG HALF-LIFE AND POTENT ANTITUMOR-ACTIVITY - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS, Journal of medicinal chemistry, 38(17), 1995, pp. 3226-3235
DERIVATIVES OF Y-2-FLUORO-BETA-D-ARABINOFURANOSYL)-5-PHENYLURACIL AND5-BENZYLURACIL - SYNTHESIS AND BIOLOGICAL PROPERTIES
Authors: DZIEWISZEK K SCHINAZI RF CHOU TC SU TL DZIK JM RODE W WATANABE KA
Citation: K. Dziewiszek et al., DERIVATIVES OF Y-2-FLUORO-BETA-D-ARABINOFURANOSYL)-5-PHENYLURACIL AND5-BENZYLURACIL - SYNTHESIS AND BIOLOGICAL PROPERTIES, Nucleosides & nucleotides, 13(1-3), 1994, pp. 77-94
HOW DO THE AGLYCONES DRIVE THE PSEUDOROTATIONAL EQUILIBRIUM OF THE PENTOFURANOSE MOIETY IN C-NUCLEOSIDES
Authors: THIBAUDEAU C PLAVEC J WATANABE KA CHATTOPADHYAYA J
Citation: C. Thibaudeau et al., HOW DO THE AGLYCONES DRIVE THE PSEUDOROTATIONAL EQUILIBRIUM OF THE PENTOFURANOSE MOIETY IN C-NUCLEOSIDES, Journal of the Chemical Society, Chemical Communications, (4), 1994, pp. 537-540
CNAD - A POTENT AND SPECIFIC INHIBITOR OF ALCOHOL-DEHYDROGENASE
Authors: GOLDSTEIN BM LI H JONES JP BELL JE ZEIDLER J PANKIEWICZ KW WATANABE KA
Citation: Bm. Goldstein et al., CNAD - A POTENT AND SPECIFIC INHIBITOR OF ALCOHOL-DEHYDROGENASE, Journal of medicinal chemistry, 37(3), 1994, pp. 392-399
SYNTHESIS AND BIOLOGICAL PROPERTIES OF 1-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)URACIL
Authors: FULCRANDELKATTAN G GOUDGAON NM ILKSOY N HUANG JT WATANABE KA SOMMADOSSI JP SCHINAZI RF
Citation: G. Fulcrandelkattan et al., SYNTHESIS AND BIOLOGICAL PROPERTIES OF 1-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)URACIL, Journal of medicinal chemistry, 37(16), 1994, pp. 2583-2588
CRYSTALLOGRAPHIC STUDIES OF ISOSTERIC NAD ANALOGS BOUND TO ALCOHOL-DEHYDROGENASE - SPECIFICITY AND SUBSTRATE-BINDING IN 2 TERNARY COMPLEXES
Authors: LI H HALLOWS WH PUNZI JS PANKIEWICZ KW WATANABE KA GOLDSTEIN BM
Citation: H. Li et al., CRYSTALLOGRAPHIC STUDIES OF ISOSTERIC NAD ANALOGS BOUND TO ALCOHOL-DEHYDROGENASE - SPECIFICITY AND SUBSTRATE-BINDING IN 2 TERNARY COMPLEXES, Biochemistry, 33(39), 1994, pp. 11734-11744
Risultati: 1-25 | 26-35