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Results: 1-25 | 26-49
Results: 1-25/49
CAFFEINE BASED MEASURES OF CYP1A2 ACTIVITY CORRELATE WITH ORAL CLEARANCE OF TACRINE IN PATIENTS WITH ALZHEIMERS-DISEASE
Authors: FONTANA RJ DEVRIES TM WOOLF TF KNAPP MJ BROWN AS KAMINSKY LS TANG BK FOSTER NL BROWN RR WATKINS PB
Citation: Rj. Fontana et al., CAFFEINE BASED MEASURES OF CYP1A2 ACTIVITY CORRELATE WITH ORAL CLEARANCE OF TACRINE IN PATIENTS WITH ALZHEIMERS-DISEASE, British journal of clinical pharmacology, 46(3), 1998, pp. 221-228
ETHANOL INCREASES RISK OF ACETAMINOPHEN HEPATOTOXICITY IN HEALTHY-ADULTS
Authors: CHIEN JY THUMMEL KE SLATTERY JT RO H NELSON SD LOWN KS WATKINS PB
Citation: Jy. Chien et al., ETHANOL INCREASES RISK OF ACETAMINOPHEN HEPATOTOXICITY IN HEALTHY-ADULTS, Hepatology, 28(4), 1998, pp. 380-380
SEQUENCES OF INTESTINAL AND HEPATIC CYTOCHROME-P450 3A4 CDNAS ARE IDENTICAL
Authors: LOWN KS GHOSH M WATKINS PB
Citation: Ks. Lown et al., SEQUENCES OF INTESTINAL AND HEPATIC CYTOCHROME-P450 3A4 CDNAS ARE IDENTICAL, Drug metabolism and disposition, 26(2), 1998, pp. 185-187
HEPATIC-DYSFUNCTION ASSOCIATED WITH TROGLITAZONE
Authors: WATKINS PB WHITCOMB RW
Citation: Pb. Watkins et Rw. Whitcomb, HEPATIC-DYSFUNCTION ASSOCIATED WITH TROGLITAZONE, The New England journal of medicine, 338(13), 1998, pp. 916-917
PREDICTING DRUG-INTERACTIONS IN-VIVO FROM EXPERIMENTS IN-VITRO - HUMAN STUDIES WITH PACLITAXEL AND KETOCONAZOLE
Authors: JAMISDOW CA PEARL ML WATKINS PB BLAKE DS KLECKER RW COLLINS JM
Citation: Ca. Jamisdow et al., PREDICTING DRUG-INTERACTIONS IN-VIVO FROM EXPERIMENTS IN-VITRO - HUMAN STUDIES WITH PACLITAXEL AND KETOCONAZOLE, American journal of clinical oncology, 20(6), 1997, pp. 592-599
THE BARRIER FUNCTION OF CYP3A4 AND P-GLYCOPROTEIN IN THE SMALL-BOWEL
Authors: WATKINS PB
Citation: Pb. Watkins, THE BARRIER FUNCTION OF CYP3A4 AND P-GLYCOPROTEIN IN THE SMALL-BOWEL, Advanced drug delivery reviews, 27(2-3), 1997, pp. 161-170
MECHANISMS OF ENHANCED ORAL AVAILABILITY OF CYP3A4 SUBSTRATES BY GRAPEFRUIT CONSTITUENTS - DECREASED ENTEROCYTE CYP3A4 CONCENTRATION AND MECHANISM-BASED INACTIVATION BY FURANOCOUMARINS
Authors: SCHMIEDLINREN P EDWARDS DJ FITZSIMMONS ME HE K LOWN KS WOSTER PM RAHMAN A THUMMEL KE FISHER JM HOLLENBERG PF WATKINS PB
Citation: P. Schmiedlinren et al., MECHANISMS OF ENHANCED ORAL AVAILABILITY OF CYP3A4 SUBSTRATES BY GRAPEFRUIT CONSTITUENTS - DECREASED ENTEROCYTE CYP3A4 CONCENTRATION AND MECHANISM-BASED INACTIVATION BY FURANOCOUMARINS, Drug metabolism and disposition, 25(11), 1997, pp. 1228-1233
EXPRESSION OF ENZYMATICALLY ACTIVE CYP3A4 BY CACO-2 CELLS GROWN ON EXTRACELLULAR MATRIX-COATED PERMEABLE SUPPORTS IN THE PRESENCE OF 1-ALPHA,25-DIHYDROXYVITAMIN D-3
Authors: SCHMIEDLINREN P THUMMEL KE FISHER JM PAINE MF LOWN KS WATKINS PB
Citation: P. Schmiedlinren et al., EXPRESSION OF ENZYMATICALLY ACTIVE CYP3A4 BY CACO-2 CELLS GROWN ON EXTRACELLULAR MATRIX-COATED PERMEABLE SUPPORTS IN THE PRESENCE OF 1-ALPHA,25-DIHYDROXYVITAMIN D-3, Molecular pharmacology, 51(5), 1997, pp. 741-754
GRAPEFRUIT JUICE INCREASES FELODIPINE ORAL AVAILABILITY IN HUMANS BY DECREASING INTESTINAL CYP3A PROTEIN EXPRESSION
Authors: LOWN KS BAILEY DG FONTANA RJ JANARDAN SK ADAIR CH FORTLAGE LA BROWN MB GUO WS WATKINS PB
Citation: Ks. Lown et al., GRAPEFRUIT JUICE INCREASES FELODIPINE ORAL AVAILABILITY IN HUMANS BY DECREASING INTESTINAL CYP3A PROTEIN EXPRESSION, The Journal of clinical investigation, 99(10), 1997, pp. 2545-2553
SHORT-TERM EFFECT OF MEDICATIONS ON CYP3A4 AND P-GLYCOPROTEIN EXPRESSION IN HUMAN INTESTINAL-MUCOSA
Authors: WILLE RT LOWN KS HUSZCZO UR SCHMIEDLINREN P WATKINS PB
Citation: Rt. Wille et al., SHORT-TERM EFFECT OF MEDICATIONS ON CYP3A4 AND P-GLYCOPROTEIN EXPRESSION IN HUMAN INTESTINAL-MUCOSA, Gastroenterology, 112(4), 1997, pp. 419-419
EFFECTS OF A CHARGRILLED MEAT DIET ON HUMAN LIVER AND INTESTINAL CYP3A4 AND CYP1A EXPRESSION
Authors: FONTANA RJ LOWN KS FORTLAGE LA JANARDAN SK ADAIR CH WATKINS PB
Citation: Rj. Fontana et al., EFFECTS OF A CHARGRILLED MEAT DIET ON HUMAN LIVER AND INTESTINAL CYP3A4 AND CYP1A EXPRESSION, Gastroenterology, 112(4), 1997, pp. 875-875
GRAPEFRUIT JUICE INCREASES FELODIPINE ORAL AVAILABILITY IN MAN BY DECREASING INTESTINAL CYP3A4 PROTEIN
Authors: LOWN KS FONTANA RJ JANARDAN SK BAILEY DG FORTLAGE LA ADAIR CH WATKINS PB
Citation: Ks. Lown et al., GRAPEFRUIT JUICE INCREASES FELODIPINE ORAL AVAILABILITY IN MAN BY DECREASING INTESTINAL CYP3A4 PROTEIN, Gastroenterology, 112(4), 1997, pp. 890-890
ROLE OF INTESTINAL P-GLYCOPROTEIN (MDR1) IN INTERPATIENT VARIATION INTHE ORAL BIOAVAILABILITY OF CYCLOSPORINE
Authors: LOWN KS MAYO RR LEICHTMAN AB HSIAO HL TURGEON DK SCHMIEDLINREN P BROWN MB GUO WS ROSSI SJ BENET LZ WATKINS PB
Citation: Ks. Lown et al., ROLE OF INTESTINAL P-GLYCOPROTEIN (MDR1) IN INTERPATIENT VARIATION INTHE ORAL BIOAVAILABILITY OF CYCLOSPORINE, Clinical pharmacology and therapeutics, 62(3), 1997, pp. 248-260
STEADY-STATE PHARMACOKINETICS OF DELAVIRDINE IN HIV-POSITIVE PATIENTS- EFFECT ON ERYTHROMYCIN BREATH TEST
Authors: CHENG CL SMITH DE CARVER PL COX SR WATKINS PB BLAKE DS KAUFFMAN CA MEYER KM AMIDON GL STETSON PL
Citation: Cl. Cheng et al., STEADY-STATE PHARMACOKINETICS OF DELAVIRDINE IN HIV-POSITIVE PATIENTS- EFFECT ON ERYTHROMYCIN BREATH TEST, Clinical pharmacology and therapeutics, 61(5), 1997, pp. 531-543
SELECTIVE EXPRESSION OF CYP3A5 AND NOT CYP3A4 IN HUMAN BLOOD
Authors: JANARDAN SK LOWN KS SCHMIEDLINREN P THUMMEL KE WATKINS PB
Citation: Sk. Janardan et al., SELECTIVE EXPRESSION OF CYP3A5 AND NOT CYP3A4 IN HUMAN BLOOD, Pharmacogenetics, 6(5), 1996, pp. 379-385
ALANINE AMINOTRANSFERASE ELEVATIONS DURING ZILEUTON THERAPY - RESULTSOF A LARGE SAFETY TRIAL
Authors: WATKINS PB MADDREY WC WRIGHT S CARPENTIER P DUBE L BIALEKSMITH S ROSENSTEIN L
Citation: Pb. Watkins et al., ALANINE AMINOTRANSFERASE ELEVATIONS DURING ZILEUTON THERAPY - RESULTSOF A LARGE SAFETY TRIAL, Hepatology, 24(4), 1996, pp. 1885-1885
THE CAFFEINE BREATH TEST DOES NOT IDENTIFY PATIENTS SUSCEPTIBLE TO TACRINE HEPATOTOXICITY
Authors: FONTANA RJ TURGEON DK WOOLF TF KNAPP MJ FOSTER NL WATKINS PB
Citation: Rj. Fontana et al., THE CAFFEINE BREATH TEST DOES NOT IDENTIFY PATIENTS SUSCEPTIBLE TO TACRINE HEPATOTOXICITY, Hepatology, 23(6), 1996, pp. 1429-1435
ERYTHROMYCIN BREATH TEST AND CLINICAL TRANSPLANTATION
Authors: WATKINS PB
Citation: Pb. Watkins, ERYTHROMYCIN BREATH TEST AND CLINICAL TRANSPLANTATION, Therapeutic drug monitoring, 18(4), 1996, pp. 368-371
BIMODAL DISTRIBUTION OF RENAL CYTOCHROME-P450 3A ACTIVITY IN HUMANS
Authors: HAEHNER BD GORSKI JC VANDENBRANDEN M WRIGHTON SA JANARDAN SK WATKINS PB HALL SD
Citation: Bd. Haehner et al., BIMODAL DISTRIBUTION OF RENAL CYTOCHROME-P450 3A ACTIVITY IN HUMANS, Molecular pharmacology, 50(1), 1996, pp. 52-59
INDUCTION OF MDR1 EXPRESSION IN NORMAL RAT AND HUMAN INTESTINE IN-VIVO
Authors: LOWN KS KOLARS JC GHOSH M SCHMIEDLINREN P WATKINS PB
Citation: Ks. Lown et al., INDUCTION OF MDR1 EXPRESSION IN NORMAL RAT AND HUMAN INTESTINE IN-VIVO, Gastroenterology, 110(4), 1996, pp. 344-344
CYP3A5 AND NOT CYP3A4 IS PRESENT IN PERIPHERAL-BLOOD
Authors: JANARDAN SK LOWN KS SCHMIEDLINREN P WATKINS PB
Citation: Sk. Janardan et al., CYP3A5 AND NOT CYP3A4 IS PRESENT IN PERIPHERAL-BLOOD, Gastroenterology, 110(4), 1996, pp. 1222-1222
IMMUNOHISTOCHEMICAL LOCALIZATION OF CYTOCHROME-P450 3A IN NORMAL AND NEOPLASTIC KIDNEY AND URINARY-BLADDER EPITHELIUM
Authors: LEGGAT JE JOHNSON KJ KOLARS JC SCHMIEDLINREN P WATKINS PB LEICHTMAN AB
Citation: Je. Leggat et al., IMMUNOHISTOCHEMICAL LOCALIZATION OF CYTOCHROME-P450 3A IN NORMAL AND NEOPLASTIC KIDNEY AND URINARY-BLADDER EPITHELIUM, The FASEB journal, 9(4), 1995, pp. 965-965
GENETIC PREDISPOSITION TO DRUG-INDUCED LIVER-DISEASE
Authors: FONTANA RJ WATKINS PB
Citation: Rj. Fontana et Pb. Watkins, GENETIC PREDISPOSITION TO DRUG-INDUCED LIVER-DISEASE, Gastroenterology clinics of North America, 24(4), 1995, pp. 811
CYCLOSPORINE AND LIVER-TRANSPLANTATION - WILL THE MIDAZOLAM TEST MAKEBLOOD LEVEL MONITORING OBSOLETE
Authors: WATKINS PB
Citation: Pb. Watkins, CYCLOSPORINE AND LIVER-TRANSPLANTATION - WILL THE MIDAZOLAM TEST MAKEBLOOD LEVEL MONITORING OBSOLETE, Hepatology, 22(3), 1995, pp. 994-996
INTERPATIENT HETEROGENEITY IN EXPRESSION OF CYP3A4 AND CYP3A5 IN SMALL-BOWEL - LACK OF PREDICTION BY THE ERYTHROMYCIN BREATH TEST (VOL 22, PG 947, 1994)
Authors: LOWN KS KOLARS JC THUMMEL KE BARNETT JL KUNZE KL WRIGHTON SA WATKINS PB
Citation: Ks. Lown et al., INTERPATIENT HETEROGENEITY IN EXPRESSION OF CYP3A4 AND CYP3A5 IN SMALL-BOWEL - LACK OF PREDICTION BY THE ERYTHROMYCIN BREATH TEST (VOL 22, PG 947, 1994), Drug metabolism and disposition, 23(3), 1995, pp. 294-294
Risultati: 1-25 | 26-49