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IDENTIFICATION OF TAMOXIFEN-DNA ADDUCTS
Authors: MARTIN EA WHITE INH TURTELTAU KW SMITH LL
Citation: Ea. Martin et al., IDENTIFICATION OF TAMOXIFEN-DNA ADDUCTS, European journal of cancer, 34, 1998, pp. 65-66
DETERMINATION OF DNA-DAMAGE IN F344 RATS INDUCED BY GEOMETRIC ISOMERSOF TAMOXIFEN AND ANALOGS
Authors: BROWN K BROWN JE MARTIN EA SMITH LL WHITE INH
Citation: K. Brown et al., DETERMINATION OF DNA-DAMAGE IN F344 RATS INDUCED BY GEOMETRIC ISOMERSOF TAMOXIFEN AND ANALOGS, Chemical research in toxicology, 11(5), 1998, pp. 527-534
ANTIESTROGEN THERAPY - UNCERTAINTIES AND RISK ASSESSMENT
Authors: SMITH LL WHITE INH
Citation: Ll. Smith et Inh. White, ANTIESTROGEN THERAPY - UNCERTAINTIES AND RISK ASSESSMENT, Oncology, 12(3), 1998, pp. 14-22
SPECIES-DIFFERENCES IN THE METABOLIC-ACTIVATION OF TAMOXIFEN INTO GENOTOXIC DERIVATIVES - RISK ASSESSMENT IN WOMEN
Authors: DEMATTEIS F WHITE INH SMITH LL
Citation: F. Dematteis et al., SPECIES-DIFFERENCES IN THE METABOLIC-ACTIVATION OF TAMOXIFEN INTO GENOTOXIC DERIVATIVES - RISK ASSESSMENT IN WOMEN, European journal of drug metabolism and pharmacokinetics, 23(3), 1998, pp. 425-428
EVALUATION OF TAMOXIFEN AND ALPHA-HYDROXYTAMOXIFEN P-32 POST-LABELED DNA-ADDUCTS BY THE DEVELOPMENT OF A NOVEL AUTOMATED ONLINE SOLID-PHASEEXTRACTION HPLC METHOD
Authors: MARTIN EA HEYDON RT BROWN K BROWN JE LIM CK WHITE INH SMITH LL
Citation: Ea. Martin et al., EVALUATION OF TAMOXIFEN AND ALPHA-HYDROXYTAMOXIFEN P-32 POST-LABELED DNA-ADDUCTS BY THE DEVELOPMENT OF A NOVEL AUTOMATED ONLINE SOLID-PHASEEXTRACTION HPLC METHOD, Carcinogenesis (New York. Print), 19(6), 1998, pp. 1061-1069
PEROXIDASE ACTIVATION OF 4-HYDROXYTAMOXIFEN TO FREE-RADICALS DETECTEDBY EPR SPECTROSCOPY
Authors: DAVIES AM MALONE ME MARTIN EA JONES RM JUKES R LIM CK SMITH LL WHITE INH
Citation: Am. Davies et al., PEROXIDASE ACTIVATION OF 4-HYDROXYTAMOXIFEN TO FREE-RADICALS DETECTEDBY EPR SPECTROSCOPY, Free radical biology & medicine, 22(3), 1997, pp. 423-431
IDENTIFICATION AND MECHANISM OF FORMATION OF POTENTIALLY GENOTOXIC METABOLITES OF TAMOXIFEN - STUDY BY LC-MS MS/
Authors: LIM CK YUAN ZX JONES RM WHITE INH SMITH LL
Citation: Ck. Lim et al., IDENTIFICATION AND MECHANISM OF FORMATION OF POTENTIALLY GENOTOXIC METABOLITES OF TAMOXIFEN - STUDY BY LC-MS MS/, Journal of pharmaceutical and biomedical analysis, 15(9-10), 1997, pp. 1335-1342
CLASTOGENIC AND ANEUGENIC EFFECTS OF TAMOXIFEN AND SOME OF ITS ANALOGS IN HEPATOCYTES FROM DOSED RATS AND IN HUMAN LYMPHOBLASTOID-CELLS TRANSFECTED WITH HUMAN P450 CDNAS (MCL-5 CELLS)
Authors: STYLES JA DAVIES A DAVIES R WHITE INH SMITH LL
Citation: Ja. Styles et al., CLASTOGENIC AND ANEUGENIC EFFECTS OF TAMOXIFEN AND SOME OF ITS ANALOGS IN HEPATOCYTES FROM DOSED RATS AND IN HUMAN LYMPHOBLASTOID-CELLS TRANSFECTED WITH HUMAN P450 CDNAS (MCL-5 CELLS), Carcinogenesis, 18(2), 1997, pp. 303-313
INVESTIGATION OF THE FORMATION AND ACCUMULATION OF LIVER DNA-ADDUCTS IN MICE CHRONICALLY EXPOSED TO TAMOXIFEN
Authors: MARTIN EA CARTHEW P WHITE INH HEYDON RT GASKELL M MAUTHE RJ TURTELTAUB KW SMITH LL
Citation: Ea. Martin et al., INVESTIGATION OF THE FORMATION AND ACCUMULATION OF LIVER DNA-ADDUCTS IN MICE CHRONICALLY EXPOSED TO TAMOXIFEN, Carcinogenesis, 18(11), 1997, pp. 2209-2215
COMPARISONS OF THE BINDING OF [C-14] RADIOLABELED TAMOXIFEN OR TOREMIFENE TO RAT DNA USING ACCELERATOR MASS-SPECTROMETRY
Authors: WHITE INH MARTIN EA MAUTHE RJ VOGEL JS TURTELTAUB KW SMITH LL
Citation: Inh. White et al., COMPARISONS OF THE BINDING OF [C-14] RADIOLABELED TAMOXIFEN OR TOREMIFENE TO RAT DNA USING ACCELERATOR MASS-SPECTROMETRY, Chemico-biological interactions, 106(2), 1997, pp. 149-160
TAMOXIFEN CAUSES GENE-MUTATIONS IN THE LIVERS OF LAMBDA LACI TRANSGENIC RATS/
Authors: DAVIES R OREFFO VIC MARTIN EA FESTING MFW WHITE INH SMITH LL STYLES JA
Citation: R. Davies et al., TAMOXIFEN CAUSES GENE-MUTATIONS IN THE LIVERS OF LAMBDA LACI TRANSGENIC RATS/, Cancer research, 57(7), 1997, pp. 1288-1293
MUTATIONAL SPECTRA OF TAMOXIFEN-INDUCED MUTATIONS IN THE LIVERS OF LACL TRANSGENIC RATS
Authors: DAVIES R OREFFO VIC BAYLISS S DINH PA LILLEY KS WHITE INH SMITH LL STYLES JA
Citation: R. Davies et al., MUTATIONAL SPECTRA OF TAMOXIFEN-INDUCED MUTATIONS IN THE LIVERS OF LACL TRANSGENIC RATS, Environmental and molecular mutagenesis, 28(4), 1996, pp. 430-433
EFFECT OF TAMOXIFEN FEEDING ON METABOLIC-ACTIVATION OF TAMOXIFEN BY THE LIVER OF THE RHESUS-MONKEY - DOES LIVER ACCUMULATION OF INHIBITORY METABOLITES PROTECT FROM TAMOXIFEN-DEPENDENT GENOTOXICITY AND CANCER
Authors: COMOGLIO A GIBBS AH WHITE INH GANT T MARTIN EA SMITH LL GAMALERO SR DEMATTEIS F
Citation: A. Comoglio et al., EFFECT OF TAMOXIFEN FEEDING ON METABOLIC-ACTIVATION OF TAMOXIFEN BY THE LIVER OF THE RHESUS-MONKEY - DOES LIVER ACCUMULATION OF INHIBITORY METABOLITES PROTECT FROM TAMOXIFEN-DEPENDENT GENOTOXICITY AND CANCER, Carcinogenesis, 17(8), 1996, pp. 1687-1693
A CONTINUOUS FLUOROMETRIC ASSAY FOR GAMMA-GLUTAMYL-TRANSPEPTIDASE
Authors: WHITE INH RAZVI N LAWRENCE RM MANSON MM
Citation: Inh. White et al., A CONTINUOUS FLUOROMETRIC ASSAY FOR GAMMA-GLUTAMYL-TRANSPEPTIDASE, Analytical biochemistry, 233(1), 1996, pp. 71-75
CHEMOPREVENTION OF BREAST-CANCER BY TAMOXIFEN - RISKS AND OPPORTUNITIES
Authors: SMITH LL WHITE INH
Citation: Ll. Smith et Inh. White, CHEMOPREVENTION OF BREAST-CANCER BY TAMOXIFEN - RISKS AND OPPORTUNITIES, Toxicology letters, 82-3, 1995, pp. 181-186
PEROXIDASE ACTIVATION OF 4-HYDROXYTAMOXIFEN TO CAUSE DNA-DAMAGE IN-VITRO
Authors: DAVIES AM MALONE ME WHITE INH
Citation: Am. Davies et al., PEROXIDASE ACTIVATION OF 4-HYDROXYTAMOXIFEN TO CAUSE DNA-DAMAGE IN-VITRO, Biochemical Society transactions, 23(3), 1995, pp. 439-439
P-32 POSTLABELED DNA-ADDUCTS IN LIVER OBTAINED FROM WOMEN TREATED WITH TAMOXIFEN
Authors: MARTIN EA RICH KJ WHITE INH WOODS KL POWLES TJ SMITH LL
Citation: Ea. Martin et al., P-32 POSTLABELED DNA-ADDUCTS IN LIVER OBTAINED FROM WOMEN TREATED WITH TAMOXIFEN, Carcinogenesis, 16(7), 1995, pp. 1651-1654
DNA-DAMAGE AS ASSESSED BY P-32 POSTLABELING IN 3 RAT STRAINS EXPOSED TO DIETARY TAMOXIFEN - THE RELATIONSHIP BETWEEN CELL-PROLIFERATION ANDLIVER-TUMOR FORMATION
Authors: CARTHEW P RICH KJ MARTIN EA DEMATTEIS F LIM CK MANSON MM FESTING MFW WHITE INH SMITH LL
Citation: P. Carthew et al., DNA-DAMAGE AS ASSESSED BY P-32 POSTLABELING IN 3 RAT STRAINS EXPOSED TO DIETARY TAMOXIFEN - THE RELATIONSHIP BETWEEN CELL-PROLIFERATION ANDLIVER-TUMOR FORMATION, Carcinogenesis, 16(6), 1995, pp. 1299-1304
PEROXIDASE ACTIVATION OF TAMOXIFEN AND TOREMIFENE RESULTING IN DNA-DAMAGE AND COVALENTLY BOUND PROTEIN ADDUCTS
Authors: DAVIES AM MARTIN EA JONES RM LIM CK SMITH LL WHITE INH
Citation: Am. Davies et al., PEROXIDASE ACTIVATION OF TAMOXIFEN AND TOREMIFENE RESULTING IN DNA-DAMAGE AND COVALENTLY BOUND PROTEIN ADDUCTS, Carcinogenesis, 16(3), 1995, pp. 539-545
GENOTOXIC EFFECTS OF 3-AMINO-1,2,4-BENZOTRIAZINE-1,4-DIOXIDE (SR-4233) AND NITROGEN MUSTARD-N-OXIDE (NITROMIN) IN WALKER CARCINOMA-CELLS UNDER AEROBIC AND HYPOXIC CONDITIONS
Authors: CAHILL A JENKINS TC PICKERING P WHITE INH
Citation: A. Cahill et al., GENOTOXIC EFFECTS OF 3-AMINO-1,2,4-BENZOTRIAZINE-1,4-DIOXIDE (SR-4233) AND NITROGEN MUSTARD-N-OXIDE (NITROMIN) IN WALKER CARCINOMA-CELLS UNDER AEROBIC AND HYPOXIC CONDITIONS, Chemico-biological interactions, 95(1-2), 1995, pp. 97-107
TAMOXIFEN INDUCES SHORT-TERM CUMULATIVE DNA-DAMAGE AND LIVER-TUMORS IN RATS - PROMOTION BY PHENOBARBITAL
Authors: CARTHEW P MARTIN EA WHITE INH DEMATTEIS F EDWARDS RE DORMAN BM HEYDON RT SMITH LL
Citation: P. Carthew et al., TAMOXIFEN INDUCES SHORT-TERM CUMULATIVE DNA-DAMAGE AND LIVER-TUMORS IN RATS - PROMOTION BY PHENOBARBITAL, Cancer research, 55(3), 1995, pp. 544-547
SPECIES-DIFFERENCES IN THE COVALENT BINDING OF [C-14] TAMOXIFEN TO LIVER-MICROSOMES AND THE FORMS OF CYTOCHROME-P450 INVOLVED
Authors: WHITE INH DEMATTEIS F GIBBS AH LIM CK WOLF CR HENDERSON C SMITH LL
Citation: Inh. White et al., SPECIES-DIFFERENCES IN THE COVALENT BINDING OF [C-14] TAMOXIFEN TO LIVER-MICROSOMES AND THE FORMS OF CYTOCHROME-P450 INVOLVED, Biochemical pharmacology, 49(8), 1995, pp. 1035-1042
CO-CHROMATOGRAPHY OF A TAMOXIFEN EPOXIDE DEOXYGUANYLIC ACID ADDUCT WITH A MAJOR DNA ADDUCT FORMED IN THE LIVERS OF TAMOXIFEN-TREATED RATS
Authors: PHILLIPS DH HEWER A WHITE INH FARMER PB
Citation: Dh. Phillips et al., CO-CHROMATOGRAPHY OF A TAMOXIFEN EPOXIDE DEOXYGUANYLIC ACID ADDUCT WITH A MAJOR DNA ADDUCT FORMED IN THE LIVERS OF TAMOXIFEN-TREATED RATS, Carcinogenesis, 15(5), 1994, pp. 793-795
A COMPARATIVE-STUDY OF TAMOXIFEN METABOLISM IN FEMALE RAT, MOUSE AND HUMAN LIVER-MICROSOMES
Authors: LIM CK YUAN ZX LAMB JH WHITE INH DEMATTEIS F SMITH LL
Citation: Ck. Lim et al., A COMPARATIVE-STUDY OF TAMOXIFEN METABOLISM IN FEMALE RAT, MOUSE AND HUMAN LIVER-MICROSOMES, Carcinogenesis, 15(4), 1994, pp. 589-593
GENOTOXICITY OF TAMOXIFEN, TAMOXIFEN EPOXIDE AND TOREMIFENE IN HUMAN LYMPHOBLASTOID-CELLS CONTAINING HUMAN CYTOCHROME P450S
Authors: STYLES JA DAVIES A LIM CK DEMATTEIS F STANLEY LA WHITE INH YUAN ZX SMITH LL
Citation: Ja. Styles et al., GENOTOXICITY OF TAMOXIFEN, TAMOXIFEN EPOXIDE AND TOREMIFENE IN HUMAN LYMPHOBLASTOID-CELLS CONTAINING HUMAN CYTOCHROME P450S, Carcinogenesis, 15(1), 1994, pp. 5-9
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