Citation: M. Widersten, HETEROLOGOUS EXPRESSION IN ESCHERICHIA-COLI OF SOLUBLE ACTIVE-SITE RANDOM MUTANTS OF HALOALKANE DEHALOGENASE FROM XANTHOBACTER AUTOTROPHICUS GJ10 BY COEXPRESSION OF MOLECULAR CHAPERONINS GROEL ES/, Protein expression and purification (Print), 13(3), 1998, pp. 389-395
Authors:
SUNDBERG K
JOHANSSON AS
STENBERG G
WIDERSTEN M
SEIDEL A
MANNERVIK B
JERNSTROM B
Citation: K. Sundberg et al., DIFFERENCES IN THE CATALYTIC EFFICIENCIES OF ALLELIC VARIANTS OF GLUTATHIONE TRANSFERASE P1-1 TOWARDS CARCINOGENIC DIOL EPOXIDES OF POLYCYCLIC AROMATIC-HYDROCARBONS, Carcinogenesis, 19(3), 1998, pp. 433-436
Authors:
JOHANSSON AS
STENBERG G
WIDERSTEN M
MANNERVIK B
Citation: As. Johansson et al., STRUCTURE-ACTIVITY-RELATIONSHIPS AND THERMAL-STABILITY OF HUMAN GLUTATHIONE TRANSFERASE P1-1 GOVERNED BY THE H-SITE RESIDUE-105, Journal of Molecular Biology, 278(3), 1998, pp. 687-698
Authors:
MANNERVIK B
CAMERON AD
FERNANDEZ E
GUSTAFSSON A
HANSSON LO
JEMTH P
JIANG FY
JONES TA
LARSSON AK
NILSSON LO
OLIN B
PETTERSSON PL
RIDDERSTROM M
STENBERG G
WIDERSTEN M
Citation: B. Mannervik et al., AN EVOLUTIONARY APPROACH TO THE DESIGN OF GLUTATHIONE-LINKED ENZYMES, Chemico-biological interactions, 112, 1998, pp. 15-21
Authors:
SUNDBERG K
WIDERSTEN M
SEIDEL A
MANNERVIK B
JERNSTROM B
Citation: K. Sundberg et al., GLUTATHIONE CONJUGATION OF BAY-REGION AND FJORD-REGION DIOL EPOXIDES OF POLYCYCLIC AROMATIC-HYDROCARBONS BY GLUTATHIONE TRANSFERASES M1-1 AND P1-1, Chemical research in toxicology, 10(11), 1997, pp. 1221-1227
Authors:
BAEZ S
SEGURAAGUILAR J
WIDERSTEN M
JOHANSSON AS
MANNERVIK B
Citation: S. Baez et al., GLUTATHIONE TRANSFERASES CATALYZE THE DETOXICATION OF OXIDIZED METABOLITES (O-QUINONES) OF CATECHOLAMINES AND MAY SERVE AS AN ANTIOXIDANT SYSTEM PREVENTING DEGENERATIVE CELLULAR PROCESSES, Biochemical journal, 324, 1997, pp. 25-28
Authors:
SEGURAAGUILAR J
BAEZ S
WIDERSTEN M
WELCH CJ
MANNERVIK B
Citation: J. Seguraaguilar et al., HUMAN CLASS MU-GLUTATHIONE TRANSFERASES, IN PARTICULAR ISOENZYME M2-2, CATALYZE DETOXICATION OF THE DOPAMINE METABOLITE AMINOCHROME, The Journal of biological chemistry, 272(9), 1997, pp. 5727-5731
Citation: Lo. Hansson et al., MECHANISM-BASED PHAGE DISPLAY SELECTION OF ACTIVE-SITE MUTANTS OF HUMAN GLUTATHIONE TRANSFERASE A1-1 CATALYZING SNAR REACTIONS, Biochemistry, 36(37), 1997, pp. 11252-11260
Authors:
JOHNSON WW
UENG YF
WIDERSTEN M
MANNERVIK B
HAYES JD
SHERRATT PJ
KETTERER B
GUENGERICH FP
Citation: Ww. Johnson et al., CONJUGATION OF HIGHLY REACTIVE AFLATOXIN B-1 EXO-8,9-EPOXIDE CATALYZED BY RAT AND HUMAN GLUTATHIONE TRANSFERASES - ESTIMATION OF KINETIC-PARAMETERS, Biochemistry, 36(11), 1997, pp. 3056-3060
Citation: M. Widersten et al., OPTIMIZED HETEROLOGOUS EXPRESSION OF THE POLYMORPHIC HUMAN GLUTATHIONE TRANSFERASE M1-1 BASED ON SILENT MUTATIONS IN THE CORRESPONDING CDNA, Protein expression and purification, 7(4), 1996, pp. 367-372
Citation: Lo. Nilsson et al., PHAGE DISPLAY SELECTION OF GLUTATHIONE TRANSFERASE A1-1 MUTANTS WITH ESTERASE-ACTIVITY, USING THEIR AFFINITY FOR A PHOSPHONATE TRANSITION-STATE ANALOG, Progress in Biophysics and Molecular Biology, 65, 1996, pp. 501-501
Citation: M. Widersten et al., INVOLVEMENT OF THE CARBOXYL GROUPS OF GLUTATHIONE IN THE CATALYTIC MECHANISM OF HUMAN GLUTATHIONE TRANSFERASE A1-1, Biochemistry, 35(24), 1996, pp. 7731-7742
Authors:
KOLM RH
STENBERG G
WIDERSTEN M
MANNERVIK B
Citation: Rh. Kolm et al., HIGH-LEVEL BACTERIAL EXPRESSION OF HUMAN GLUTATHIONE TRANSFERASE P1-1ENCODED BY SEMISYNTHETIC DNA, Protein expression and purification, 6(3), 1995, pp. 265-271
Authors:
YILMAZ S
WIDERSTEN M
EMAHAZION T
MANNERVIK B
Citation: S. Yilmaz et al., GENERATION OF A NI(II) BINDING-SITE BY INTRODUCTION OF A HISTIDINE CLUSTER IN THE STRUCTURE OF HUMAN GLUTATHIONE TRANSFERASE A1-1, Protein engineering, 8(11), 1995, pp. 1163-1169
Citation: M. Widersten et B. Mannervik, GLUTATHIONE TRANSFERASES WITH NOVEL ACTIVE-SITES ISOLATED BY PHAGE DISPLAY FROM A LIBRARY OF RANDOM MUTANTS, Journal of Molecular Biology, 250(2), 1995, pp. 115-122
Authors:
BJORNESTEDT R
STENBERG G
WIDERSTEN M
BOARD PG
SINNING I
JONES TA
MANNERVIK B
Citation: R. Bjornestedt et al., FUNCTIONAL-SIGNIFICANCE OF ARGININE-15 IN THE ACTIVE-SITE OF HUMAN CLASS-ALPHA GLUTATHIONE TRANSFERASE A1-1, Journal of Molecular Biology, 247(4), 1995, pp. 765-773
Authors:
MANNERVIK B
WIDERSTEN M
STENBERG G
BERHANE K
BJORNESTEDT R
TARDIOLI S
KOLM R
Citation: B. Mannervik et al., DESIGN OF GLUTATHIONE TRANSFERASES BY EVOLUTION AND BY PROTEIN ENGINEERING, The FASEB journal, 8(7), 1994, pp. 10001256-10001256
Authors:
CHAGA G
WIDERSTEN M
ANDERSSON L
PORATH J
DANIELSON UH
MANNERVIK B
Citation: G. Chaga et al., ENGINEERING OF A METAL COORDINATING SITE INTO HUMAN GLUTATHIONE TRANSFERASE M1-1 BASED ON IMMOBILIZED METAL-ION AFFINITY-CHROMATOGRAPHY OF HOMOLOGOUS RAT ENZYMES, Protein engineering, 7(9), 1994, pp. 1115-1119
Authors:
HAO XY
WIDERSTEN M
RIDDERSTROM M
HELLMAN U
MANNERVIK B
Citation: Xy. Hao et al., CO-VARIATION OF GLUTATHIONE TRANSFERASE EXPRESSION AND CYTOSTATIC DRUG-RESISTANCE IN HELA-CELLS - ESTABLISHMENT OF CLASS-MU GLUTATHIONE TRANSFERASE M3-3 AS THE DOMINATING ISOENZYME, Biochemical journal, 297, 1994, pp. 59-67
Authors:
BERHANE K
WIDERSTEN M
ENGSTROM A
KOZARICH JW
MANNERVIK B
Citation: K. Berhane et al., DETOXICATION OF BASE PROPENALS AND OTHER ALPHA,BETA-UNSATURATED ALDEHYDE PRODUCTS OF RADICAL REACTIONS AND LIPID-PEROXIDATION BY HUMAN GLUTATHIONE TRANSFERASES, Proceedings of the National Academy of Sciences of the United Statesof America, 91(4), 1994, pp. 1480-1484
Citation: M. Widersten et al., CONTRIBUTION OF AMINO-ACID RESIDUE-208 IN THE HYDROPHOBIC BINDING-SITE TO THE CATALYTIC MECHANISM OF HUMAN GLUTATHIONE TRANSFERASE-A1-1, Biochemistry, 33(39), 1994, pp. 11717-11723
Authors:
COMSTOCK KE
WIDERSTEN M
HAO XY
HENNER WD
MANNERVIK B
Citation: Ke. Comstock et al., A COMPARISON OF THE ENZYMATIC AND PHYSICOCHEMICAL PROPERTIES OF HUMANGLUTATHIONE TRANSFERASE M4-4 AND 3 OTHER HUMAN MU-CLASS ENZYMES, Archives of biochemistry and biophysics, 311(2), 1994, pp. 487-495