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Results: 1-15 |
Results: 15
BIOTRANSFORMATION OF TIRILAZAD IN HUMAN - 3 - TIRILAZAD A-RING REDUCTION BY HUMAN LIVER MICROSOMAL 5-ALPHA-REDUCTASE TYPE-1 AND TYPE-2
Authors: WIENKERS LC STEENWYK RC HAUER MJ FLEISHAKER JC PEARSON PG
Citation: Lc. Wienkers et al., BIOTRANSFORMATION OF TIRILAZAD IN HUMAN - 3 - TIRILAZAD A-RING REDUCTION BY HUMAN LIVER MICROSOMAL 5-ALPHA-REDUCTASE TYPE-1 AND TYPE-2, The Journal of pharmacology and experimental therapeutics, 287(2), 1998, pp. 583-590
BIOTRANSFORMATION OF TIRILAZAD IN HUMAN - 4 - EFFECT OF FINASTERIDE ON TIRILAZAD CLEARANCE AND REDUCED METABOLITE FORMATION
Authors: FLEISHAKER JC PEARSON PG WIENKERS LC PEARSON LK MOORE TA PETERS GR
Citation: Jc. Fleishaker et al., BIOTRANSFORMATION OF TIRILAZAD IN HUMAN - 4 - EFFECT OF FINASTERIDE ON TIRILAZAD CLEARANCE AND REDUCED METABOLITE FORMATION, The Journal of pharmacology and experimental therapeutics, 287(2), 1998, pp. 591-597
BIOACTIVATION OF THE ANTICANCER AGENT CPT-11 TO SN-38 BY HUMAN HEPATIC-MICROSOMAL CARBOXYLESTERASES AND THE IN-VITRO ASSESSMENT OF POTENTIAL-DRUG INTERACTIONS
Authors: SLATTER JG SU P SAMS JP SCHAAF LJ WIENKERS LC
Citation: Jg. Slatter et al., BIOACTIVATION OF THE ANTICANCER AGENT CPT-11 TO SN-38 BY HUMAN HEPATIC-MICROSOMAL CARBOXYLESTERASES AND THE IN-VITRO ASSESSMENT OF POTENTIAL-DRUG INTERACTIONS, Drug metabolism and disposition, 25(10), 1997, pp. 1157-1164
ASSESSMENT OF POTENTIAL INTERACTIONS BETWEEN DOPAMINE-RECEPTOR AGONISTS AND VARIOUS HUMAN CYTOCHROME-P450 ENZYMES USING A SIMPLE IN-VITRO INHIBITION SCREEN
Authors: WYNALDA MA WIENKERS LC
Citation: Ma. Wynalda et Lc. Wienkers, ASSESSMENT OF POTENTIAL INTERACTIONS BETWEEN DOPAMINE-RECEPTOR AGONISTS AND VARIOUS HUMAN CYTOCHROME-P450 ENZYMES USING A SIMPLE IN-VITRO INHIBITION SCREEN, Drug metabolism and disposition, 25(10), 1997, pp. 1211-1214
IN-VITRO METABOLIC TRANSFORMATIONS OF 2,4-DIPYRROLIDINYLPYRIMIDINE - A CHEMICAL PROBE FOR P450-MEDIATED OXIDATION OF TIRILAZAD MESYLATE
Authors: STREEPER RT PEARSON PG ZHAO Z MIZSAK SA SANDERS PE WIENKERS LC VRBANAC JJ
Citation: Rt. Streeper et al., IN-VITRO METABOLIC TRANSFORMATIONS OF 2,4-DIPYRROLIDINYLPYRIMIDINE - A CHEMICAL PROBE FOR P450-MEDIATED OXIDATION OF TIRILAZAD MESYLATE, Xenobiotica, 27(11), 1997, pp. 1131-1145
FINASTERIDE INHIBITS FORMATION OF REDUCED ACTIVE METABOLITES OF TIRILAZAD
Authors: FLEISHAKER JC PEARSON LK PEARSON PG WIENKERS LC MOORE TA PETERS GR
Citation: Jc. Fleishaker et al., FINASTERIDE INHIBITS FORMATION OF REDUCED ACTIVE METABOLITES OF TIRILAZAD, Clinical pharmacology and therapeutics, 61(2), 1997, pp. 78-78
FORMATION OF (R)-8-HYDROXYWARFARIN IN HUMAN LIVER-MICROSOMES - A NEW METABOLIC MARKER FOR THE (S)-MEPHENYTOIN HYDROXYLASE, P4502C19
Authors: WIENKERS LC WURDEN CJ STORCH E KUNZE KL RETTIE AE TRAGER WF
Citation: Lc. Wienkers et al., FORMATION OF (R)-8-HYDROXYWARFARIN IN HUMAN LIVER-MICROSOMES - A NEW METABOLIC MARKER FOR THE (S)-MEPHENYTOIN HYDROXYLASE, P4502C19, Drug metabolism and disposition, 24(5), 1996, pp. 610-614
WARFARIN-FLUCONAZOLE .1. INHIBITION OF THE HUMAN CYTOCHROME-P450-DEPENDENT METABOLISM OF WARFARIN BY FLUCONAZOLE - IN-VITRO STUDIES
Authors: KUNZE KL WIENKERS LC THUMMEL KE TRAGER WF
Citation: Kl. Kunze et al., WARFARIN-FLUCONAZOLE .1. INHIBITION OF THE HUMAN CYTOCHROME-P450-DEPENDENT METABOLISM OF WARFARIN BY FLUCONAZOLE - IN-VITRO STUDIES, Drug metabolism and disposition, 24(4), 1996, pp. 414-421
WARFARIN-FLUCONAZOLE .2. A METABOLICALLY BASED DRUG-INTERACTION - IN-VIVO STUDIES
Authors: BLACK DJ KUNZE KL WIENKERS LC GIDAL BE SEATON TL MCDONNELL ND EVANS JS BAUWENS E TRAGER WF
Citation: Dj. Black et al., WARFARIN-FLUCONAZOLE .2. A METABOLICALLY BASED DRUG-INTERACTION - IN-VIVO STUDIES, Drug metabolism and disposition, 24(4), 1996, pp. 422-428
BIOTRANSFORMATION OF TIRILAZAD IN HUMAN .1. CYTOCHROME-P450 3A-MEDIATED HYDROXYLATION OF TIRILAZAD MESYLATE IN HUMAN LIVER-MICROSOMES
Authors: WIENKERS LC STEENWYK RC SANDERS PE PEARSON PG
Citation: Lc. Wienkers et al., BIOTRANSFORMATION OF TIRILAZAD IN HUMAN .1. CYTOCHROME-P450 3A-MEDIATED HYDROXYLATION OF TIRILAZAD MESYLATE IN HUMAN LIVER-MICROSOMES, The Journal of pharmacology and experimental therapeutics, 277(2), 1996, pp. 982-990
BIOTRANSFORMATION OF TIRILAZAD IN HUMAN .2. EFFECT OF KETOCONAZOLE ONTIRILAZAD CLEARANCE AND ORAL BIOAVAILABILITY
Authors: FLEISHAKER JC PEARSON PG WIENKERS LC PEARSON LK PETERS GR
Citation: Jc. Fleishaker et al., BIOTRANSFORMATION OF TIRILAZAD IN HUMAN .2. EFFECT OF KETOCONAZOLE ONTIRILAZAD CLEARANCE AND ORAL BIOAVAILABILITY, The Journal of pharmacology and experimental therapeutics, 277(2), 1996, pp. 991-998
IN-VITRO METABOLISM OF TIRILAZAD MESYLATE IN MALE AND FEMALE RATS - CONTRIBUTION OF CYTOCHROME P4502C11 AND DELTA(4)-5-ALPHA-REDUCTASE
Authors: WIENKERS LC STEENWYK RC MIZSAK SA PEARSON PG
Citation: Lc. Wienkers et al., IN-VITRO METABOLISM OF TIRILAZAD MESYLATE IN MALE AND FEMALE RATS - CONTRIBUTION OF CYTOCHROME P4502C11 AND DELTA(4)-5-ALPHA-REDUCTASE, Drug metabolism and disposition, 23(3), 1995, pp. 383-392
IMPAIRED (S)-WARFARIN METABOLISM CATALYZED BY THE R144C ALLELIC VARIANT OF CYP2C9
Authors: RETTIE AE WIENKERS LC GONZALEZ FJ TRAGER WF KORZEKWA KR
Citation: Ae. Rettie et al., IMPAIRED (S)-WARFARIN METABOLISM CATALYZED BY THE R144C ALLELIC VARIANT OF CYP2C9, Pharmacogenetics, 4(1), 1994, pp. 39-42
RELATIONSHIPS BETWEEN THE LEVELS OF CYTOCHROME P4502C9 AND ITS PROTOTYPIC CATALYTIC ACTIVITIES IN HUMAN LIVER-MICROSOMES
Authors: HALL SD HAMMAN MA RETTIE AE WIENKERS LC TRAGER WF VANDENBRANDEN M WRIGHTON SA
Citation: Sd. Hall et al., RELATIONSHIPS BETWEEN THE LEVELS OF CYTOCHROME P4502C9 AND ITS PROTOTYPIC CATALYTIC ACTIVITIES IN HUMAN LIVER-MICROSOMES, Drug metabolism and disposition, 22(6), 1994, pp. 975-978
ROLE OF HUMAN MICROSOMAL AND HUMAN COMPLEMENTARY DNA-EXPRESSED CYTOCHROME-P4501A2 AND CYTOCHROME-P4503A4 IN THE BIOACTIVATION OF AFLATOXIN-B(1)
Authors: GALLAGHER EP WIENKERS LC STAPLETON PL KUNZE KL EATON DL
Citation: Ep. Gallagher et al., ROLE OF HUMAN MICROSOMAL AND HUMAN COMPLEMENTARY DNA-EXPRESSED CYTOCHROME-P4501A2 AND CYTOCHROME-P4503A4 IN THE BIOACTIVATION OF AFLATOXIN-B(1), Cancer research, 54(1), 1994, pp. 101-108
Risultati: 1-15 |