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Results: 1-25 | 26-50 | 51-52
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AN ADDITIONAL DEFECTIVE ALLELE, CYP2C19-ASTERISK-5, CONTRIBUTES TO THE S-MEPHENYTOIN POOR METABOLIZER PHENOTYPE IN CAUCASIANS
Authors: IBEANU GC BLAISDELL J GHANAYEM BI BEYELER C BENHAMOU S BOUCHARDY C WILKINSON GR DAYER P DALY AK GOLDSTEIN JA
Citation: Gc. Ibeanu et al., AN ADDITIONAL DEFECTIVE ALLELE, CYP2C19-ASTERISK-5, CONTRIBUTES TO THE S-MEPHENYTOIN POOR METABOLIZER PHENOTYPE IN CAUCASIANS, Pharmacogenetics, 8(2), 1998, pp. 129-135
IN-VITRO AND IN-VIVO DRUG-INTERACTIONS INVOLVING HUMAN CYP3A
Authors: THUMMEL KE WILKINSON GR
Citation: Ke. Thummel et Gr. Wilkinson, IN-VITRO AND IN-VIVO DRUG-INTERACTIONS INVOLVING HUMAN CYP3A, Annual review of pharmacology and toxicology, 38, 1998, pp. 389-430
A NEW GENETIC-DEFECT IN HUMAN CYP2C19 - MUTATION OF THE INITIATION CODON IS RESPONSIBLE FOR POOR METABOLISM OF S-MEPHENYTOIN
Authors: FERGUSON RJ DEMORAIS SMF BENHAMOU S BOUCHARDY C BLAISDELL J IBEANU G WILKINSON GR SARICH TC WRIGHT JM DAYER P GOLDSTEIN JA
Citation: Rj. Ferguson et al., A NEW GENETIC-DEFECT IN HUMAN CYP2C19 - MUTATION OF THE INITIATION CODON IS RESPONSIBLE FOR POOR METABOLISM OF S-MEPHENYTOIN, The Journal of pharmacology and experimental therapeutics, 284(1), 1998, pp. 356-361
THE BLESSINGS OF WAR - THE DEPICTION OF MILITARY FORCE IN EDWARDIAN NEWSPAPERS
Authors: WILKINSON GR
Citation: Gr. Wilkinson, THE BLESSINGS OF WAR - THE DEPICTION OF MILITARY FORCE IN EDWARDIAN NEWSPAPERS, Journal of contemporary history, 33(1), 1998, pp. 97-115
THE DRUG TRANSPORTER P-GLYCOPROTEIN LIMITS ORAL ABSORPTION AND BRAIN ENTRY OF HIV-1 PROTEASE INHIBITORS
Authors: KIM RB FROMM MF WANDEL C LEAKE B WOOD AJJ RODEN DM WILKINSON GR
Citation: Rb. Kim et al., THE DRUG TRANSPORTER P-GLYCOPROTEIN LIMITS ORAL ABSORPTION AND BRAIN ENTRY OF HIV-1 PROTEASE INHIBITORS, The Journal of clinical investigation, 101(2), 1998, pp. 289-294
SELECTIVE EFFECT OF LIVER-DISEASE ON THE ACTIVITIES OF SPECIFIC METABOLIZING ENZYMES - INVESTIGATION OF CYTOCHROMES P450 2C19 AND 2D6
Authors: ADEDOYIN A ARNS PA RICHARDS WO WILKINSON GR BRANCH RA
Citation: A. Adedoyin et al., SELECTIVE EFFECT OF LIVER-DISEASE ON THE ACTIVITIES OF SPECIFIC METABOLIZING ENZYMES - INVESTIGATION OF CYTOCHROMES P450 2C19 AND 2D6, Clinical pharmacology and therapeutics, 64(1), 1998, pp. 8-17
MODULATION OF CYTOCHROME-P450 ENZYME-ACTIVITY BY RESVERATROL
Authors: DELAPORTE E WILKINSON GR
Citation: E. Delaporte et Gr. Wilkinson, MODULATION OF CYTOCHROME-P450 ENZYME-ACTIVITY BY RESVERATROL, Clinical pharmacology and therapeutics, 63(2), 1998, pp. 48-48
TRANSPORT OF P450 (CYP) DRUG SUBSTRATES BY P-GLYCOPROTEIN
Authors: KIM RB LEAKE B CVETKOVIC M WANDEL C RODEN MM FROMM MF CHAUDHARY AK BELAS F RODEN DM WOOD AJJ WILKINSON GR
Citation: Rb. Kim et al., TRANSPORT OF P450 (CYP) DRUG SUBSTRATES BY P-GLYCOPROTEIN, Clinical pharmacology and therapeutics, 63(2), 1998, p.
QT PROLONGATION BY QUINIDINE IS DETERMINED BY SYMPATHETIC ACTIVATION
Authors: DARBAR D FROMM MF DELLORTO S WILKINSON GR RODEN DM
Citation: D. Darbar et al., QT PROLONGATION BY QUINIDINE IS DETERMINED BY SYMPATHETIC ACTIVATION, Circulation, 98(17), 1998, pp. 125-125
SALT LOADING INCREASES QUINIDINES ORAL CLEARANCE - UNDERLYING MECHANISMS
Authors: FROMM MF DARBAR D DELLORTO S WILKINSON GR RODEN DM
Citation: Mf. Fromm et al., SALT LOADING INCREASES QUINIDINES ORAL CLEARANCE - UNDERLYING MECHANISMS, Circulation, 98(17), 1998, pp. 4416-4416
MODULATION OF CYP2EI ACTIVITY BY ISONIAZID IN RAPID AND SLOW N-ACETYLATORS
Authors: OSHEA D RIM RB WILKINSON GR
Citation: D. Oshea et al., MODULATION OF CYP2EI ACTIVITY BY ISONIAZID IN RAPID AND SLOW N-ACETYLATORS, British journal of clinical pharmacology, 43(1), 1997, pp. 99-103
THE EFFECTS OF DIET, AGING AND DISEASE-STATES ON PRESYSTEMIC ELIMINATION AND ORAL-DRUG BIOAVAILABILITY IN HUMANS
Authors: WILKINSON GR
Citation: Gr. Wilkinson, THE EFFECTS OF DIET, AGING AND DISEASE-STATES ON PRESYSTEMIC ELIMINATION AND ORAL-DRUG BIOAVAILABILITY IN HUMANS, Advanced drug delivery reviews, 27(2-3), 1997, pp. 129-159
CHARACTERIZATION OF THE HEPATIC CANALICULAR MEMBRANE-TRANSPORT OF A MODEL OLIGOPEPTIDE - DITEKIREN
Authors: TAKAHASHI H KIM RB PERRY PR WILKINSON GR
Citation: H. Takahashi et al., CHARACTERIZATION OF THE HEPATIC CANALICULAR MEMBRANE-TRANSPORT OF A MODEL OLIGOPEPTIDE - DITEKIREN, The Journal of pharmacology and experimental therapeutics, 281(1), 1997, pp. 297-303
MEPHENYTOIN DISPOSITION AND SERUM BILE-ACIDS AS INDEXES OF HEPATIC-FUNCTION IN CHRONIC VIRAL-HEPATITIS
Authors: ARNS PA ADEDOYIN A DIBISCEGLIE AM WAGGONER JG HOOFNAGLE JH WILKINSON GR BRANCH RA
Citation: Pa. Arns et al., MEPHENYTOIN DISPOSITION AND SERUM BILE-ACIDS AS INDEXES OF HEPATIC-FUNCTION IN CHRONIC VIRAL-HEPATITIS, Clinical pharmacology and therapeutics, 62(5), 1997, pp. 527-537
DIETARY SALT INCREASES FIRST-PASS ELIMINATION OF ORAL QUINIDINE
Authors: DARBAR D DELLORTO S MORIKE K WILKINSON GR RODEN DM
Citation: D. Darbar et al., DIETARY SALT INCREASES FIRST-PASS ELIMINATION OF ORAL QUINIDINE, Clinical pharmacology and therapeutics, 61(3), 1997, pp. 292-300
HIGH-AFFINITY UPTAKE BY ISOLATED RAT HEPATOCYTES OF A LINEAR PSEUDO-HEXAPEPTIDE, DITEKIREN
Authors: KIM RB PERRY PR WILKINSON GR
Citation: Rb. Kim et al., HIGH-AFFINITY UPTAKE BY ISOLATED RAT HEPATOCYTES OF A LINEAR PSEUDO-HEXAPEPTIDE, DITEKIREN, Biochimica et biophysica acta. Biomembranes, 1328(1), 1997, pp. 41-47
THE RELATIONSHIP BETWEEN CYTOCHROME P4502E1 ACTIVITY AND PLASMA FLUORIDE LEVELS AFTER SEVOFLURANE ANESTHESIA IN HUMANS
Authors: WANDEL C NEFF S KEPPLER G BOHRER H STOCKINGER K WILKINSON GR WOOD M MARTIN E
Citation: C. Wandel et al., THE RELATIONSHIP BETWEEN CYTOCHROME P4502E1 ACTIVITY AND PLASMA FLUORIDE LEVELS AFTER SEVOFLURANE ANESTHESIA IN HUMANS, Anesthesia and analgesia, 85(4), 1997, pp. 924-930
LOSS OF QUINIDINE GLUCONATE INJECTION IN A POLYVINYL-CHLORIDE INFUSION SYSTEM
Authors: DARBAR D DELLORTO S WILKINSON GR RODEN DM
Citation: D. Darbar et al., LOSS OF QUINIDINE GLUCONATE INJECTION IN A POLYVINYL-CHLORIDE INFUSION SYSTEM, American journal of health-system pharmacy, 53(6), 1996, pp. 655-658
GENETIC-POLYMORPHISM OF S-MEPHENYTOIN 4'-HYDROXYLATION IN AFRICAN-AMERICANS
Authors: EDEKI TI GOLDSTEIN JA DEMORAIS SMF HAJILOO L BUTLER M CHAPDELAINE P WILKINSON GR
Citation: Ti. Edeki et al., GENETIC-POLYMORPHISM OF S-MEPHENYTOIN 4'-HYDROXYLATION IN AFRICAN-AMERICANS, Pharmacogenetics, 6(4), 1996, pp. 357-360
CYP2E1 ACTIVITY IS NOT ALTERED BY INFLUENZA VACCINATION
Authors: KIM RB WILKINSON GR
Citation: Rb. Kim et Gr. Wilkinson, CYP2E1 ACTIVITY IS NOT ALTERED BY INFLUENZA VACCINATION, British journal of clinical pharmacology, 42(4), 1996, pp. 529-530
DISPOSITION OF DIAZEPAM IN YOUNG AND ELDERLY SUBJECTS AFTER ACUTE ANDCHRONIC DOSING
Authors: HERMAN RJ WILKINSON GR
Citation: Rj. Herman et Gr. Wilkinson, DISPOSITION OF DIAZEPAM IN YOUNG AND ELDERLY SUBJECTS AFTER ACUTE ANDCHRONIC DOSING, British journal of clinical pharmacology, 42(2), 1996, pp. 147-155
CYTOCHROME P4503A (CYP3A) METABOLISM - PREDICTION OF IN-VIVO ACTIVITYIN HUMANS
Authors: WILKINSON GR
Citation: Gr. Wilkinson, CYTOCHROME P4503A (CYP3A) METABOLISM - PREDICTION OF IN-VIVO ACTIVITYIN HUMANS, Journal of pharmacokinetics and biopharmaceutics, 24(5), 1996, pp. 475-490
IN-VIVO AND IN-VITRO CHARACTERIZATION OF CYP2E1 ACTIVITY IN JAPANESE AND CAUCASIANS
Authors: KIM RB YAMAZAKI H CHIBA K OSHEA D MIMURA M GUENGERICH FP ISHIZAKI T SHIMADA T WILKINSON GR
Citation: Rb. Kim et al., IN-VIVO AND IN-VITRO CHARACTERIZATION OF CYP2E1 ACTIVITY IN JAPANESE AND CAUCASIANS, The Journal of pharmacology and experimental therapeutics, 279(1), 1996, pp. 4-11
DIFFERENCES BETWEEN WHITE SUBJECTS AND CHINESE SUBJECTS IN THE IN-VIVO INHIBITION OF CYTOCHROME P450S 2C19, 2D6, AND 3A BY OMEPRAZOLE
Authors: CARACO Y WILKINSON GR WOOD AJJ
Citation: Y. Caraco et al., DIFFERENCES BETWEEN WHITE SUBJECTS AND CHINESE SUBJECTS IN THE IN-VIVO INHIBITION OF CYTOCHROME P450S 2C19, 2D6, AND 3A BY OMEPRAZOLE, Clinical pharmacology and therapeutics, 60(4), 1996, pp. 396-404
ORAL FIRST-PASS ELIMINATION OF MIDAZOLAM INVOLVES BOTH GASTROINTESTINAL AND HEPATIC CYP3A-MEDIATED METABOLISM
Authors: THUMMEL KE OSHEA D PAINE MF SHEN DD KUNZE KL PERKINS JD WILKINSON GR
Citation: Ke. Thummel et al., ORAL FIRST-PASS ELIMINATION OF MIDAZOLAM INVOLVES BOTH GASTROINTESTINAL AND HEPATIC CYP3A-MEDIATED METABOLISM, Clinical pharmacology and therapeutics, 59(5), 1996, pp. 491-502
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