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Results: 1-7 |
Results: 7
ORALLY-ACTIVE TRIFLUOROMETHYL KETONE INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE
Authors: VEALE CA BERNSTEIN PR BOHNERT CM BROWN FJ BRYANT C DAMEWOOD JR EARLEY R FEENEY SW EDWARDS PD GOMES B HULSIZER JM KOSMIDER BJ KRELL RD MOORE G SALCEDO TW SHAW A SILBERSTEIN DS STEELMAN GB STEIN M STRIMPLER A THOMAS RM VACEK EP WILLIAMS JC WOLANIN DJ WOOLSON S
Citation: Ca. Veale et al., ORALLY-ACTIVE TRIFLUOROMETHYL KETONE INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE, Journal of medicinal chemistry, 40(20), 1997, pp. 3173-3181
DISCOVERY AND BIOLOGICAL-ACTIVITY OR ORALLY-ACTIVE PEPTIDYL TRIFLUOROMETHYL KETONE INHIBITORS OF HUMAN NEUTROPHIL ELASTASE
Authors: EDWARDS PD ANDISIK DW BRYANT CA EWING B GOMES B LEWIS JJ RAKIEWICZ D STEELMAN G STRIMPLER A TRAINOR DA TUTHILL PA MAUGER RC VEALE CA WILDONGER RA WILLIAMS JC WOLANIN DJ ZOTTOLA M
Citation: Pd. Edwards et al., DISCOVERY AND BIOLOGICAL-ACTIVITY OR ORALLY-ACTIVE PEPTIDYL TRIFLUOROMETHYL KETONE INHIBITORS OF HUMAN NEUTROPHIL ELASTASE, Journal of medicinal chemistry, 40(12), 1997, pp. 1876-1885
PEPTIDYL ALPHA-KETOHETEROCYCLIC INHIBITORS OF HUMAN NEUTROPHIL ELASTASE .2. EFFECT OF VARYING THE HETEROCYCLIC RING ON IN-VITRO POTENCY
Authors: EDWARDS PD WOLANIN DJ ANDISIK DW DAVIS MW
Citation: Pd. Edwards et al., PEPTIDYL ALPHA-KETOHETEROCYCLIC INHIBITORS OF HUMAN NEUTROPHIL ELASTASE .2. EFFECT OF VARYING THE HETEROCYCLIC RING ON IN-VITRO POTENCY, Journal of medicinal chemistry, 38(1), 1995, pp. 76-85
NONPEPTIDIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .5. DESIGN, SYNTHESIS, AND X-RAY CRYSTALLOGRAPHY OF A SERIES OF ORALLY-ACTIVE 5-AMINOPYRIMIDIN-6-ONE-CONTAINING TRIFLUOROMETHYL KETONES
Authors: VEALE CA BERNSTEIN PR BRYANT C CECCARELLI C DAMEWOOD JR EARLEY R FEENEY SW GOMES B KOSMIDER BJ STEELMAN GB THOMAS RM VACEK EP WILLIAMS JC WOLANIN DJ WOOLSON S
Citation: Ca. Veale et al., NONPEPTIDIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .5. DESIGN, SYNTHESIS, AND X-RAY CRYSTALLOGRAPHY OF A SERIES OF ORALLY-ACTIVE 5-AMINOPYRIMIDIN-6-ONE-CONTAINING TRIFLUOROMETHYL KETONES, Journal of medicinal chemistry, 38(1), 1995, pp. 98-108
DESIGN OF ORALLY-ACTIVE, NONPEPTIDIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE
Authors: BROWN FJ ANDISIK DW BERNSTEIN PR BRYANT CB CECCARELLI C DAMEWOOD JR WOOLSON SA EDWARDS PD EARLEY RA FEENEY S GREEN RC GOMES B KOSMIDER BJ KRELL RD SHAW A STEELMAN GB THOMAS RN VACEK EP VEALE CA TUTHILL PA WARNER P WILLIAMS JC WOLANIN DJ
Citation: Fj. Brown et al., DESIGN OF ORALLY-ACTIVE, NONPEPTIDIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE, Journal of medicinal chemistry, 37(9), 1994, pp. 1259-1261
NONPEPTIDIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .2. DESIGN, SYNTHESIS, AND IN-VITRO ACTIVITY OF A SERIES OF 3-AMINO-6-ARYLOPYRIDIN-2-ONETRIFLUOROMETHYL KETONES
Authors: DAMEWOOD JR EDWARDS PD FEENEY S GOMES BC STEELMAN GB TUTHILL PA WILIIAMS JC WARNER P WOOLSON SA WOLANIN DJ VEALE CA
Citation: Jr. Damewood et al., NONPEPTIDIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .2. DESIGN, SYNTHESIS, AND IN-VITRO ACTIVITY OF A SERIES OF 3-AMINO-6-ARYLOPYRIDIN-2-ONETRIFLUOROMETHYL KETONES, Journal of medicinal chemistry, 37(20), 1994, pp. 3303-3312
NONPEPTIDIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .3. DESIGN, SYNTHESIS, X-RAY CRYSTALLOGRAPHIC ANALYSIS, AND STRUCTURE-ACTIVITY-RELATIONSHIPS FOR A SERIES OF ORALLY-ACTIVE 3-AMINO-6-PHENYLPYRIDIN-2-ONE TRIFLUOROMETHYL KETONES
Authors: BERNSTEIN PR ANDISIK D BRADLEY PK BRYANT CB CECCARELLI C DAMEWOOD JR EARLEY R EDWARDS PD FEENEY S GOMES BC KOSMIDER BJ STEELMAN GB THOMAS RM VACEK EP VEALE CA WILLIAMS JC WOLANIN DJ WOOLSON SA
Citation: Pr. Bernstein et al., NONPEPTIDIC INHIBITORS OF HUMAN-LEUKOCYTE ELASTASE .3. DESIGN, SYNTHESIS, X-RAY CRYSTALLOGRAPHIC ANALYSIS, AND STRUCTURE-ACTIVITY-RELATIONSHIPS FOR A SERIES OF ORALLY-ACTIVE 3-AMINO-6-PHENYLPYRIDIN-2-ONE TRIFLUOROMETHYL KETONES, Journal of medicinal chemistry, 37(20), 1994, pp. 3313-3326
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