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Results: 1-25/59
Authors:
Forbes, AJ
Mazur, MT
Patel, HM
Walsh, CT
Kelleher, NL
Citation: Aj. Forbes et al., Toward efficient analysis of > 70 kDa proteins with 100% sequence coverage, PROTEOMICS, 1(8), 2001, pp. 927-933
Authors:
Forbes, AJ
Mazur, MT
Kelleher, NL
Patel, HM
Walsh, CT
Citation: Aj. Forbes et al., Toward efficient analysis of > 70 kDa proteins with 100% sequence coverage, EUR J MASS, 7(2), 2001, pp. 81-87
Authors:
Keating, TA
Ehmann, DE
Kohli, RM
Marshall, CG
Trauger, JW
Walsh, CT
Citation: Ta. Keating et al., Chain termination steps in nonribosomal peptide synthetase assembly lines:Directed acyl-S-enzyme breakdown in antibiotic and siderophore biosynthesis, CHEMBIOCHEM, 2(2), 2001, pp. 99-107
Authors:
Walsh, CT
Chen, HW
Keating, TA
Hubbard, BK
Losey, HC
Luo, LS
Marshall, CG
Miller, DA
Patel, HM
Citation: Ct. Walsh et al., Tailoring enzymes that modify nonribosomal peptides during and after chainelongation on NRPS assembly lines, CURR OP C B, 5(5), 2001, pp. 525-534
Authors:
Chen, HW
O'Connor, S
Cane, DE
Walsh, CT
Citation: Hw. Chen et al., Epothilone biosynthesis: assembly of the methylthiazolylcarboxy starter unit on the EpoB subunit, CHEM BIOL, 8(9), 2001, pp. 899-912
Authors:
Chen, HW
Walsh, CT
Citation: Hw. Chen et Ct. Walsh, Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI, CHEM BIOL, 8(4), 2001, pp. 301-312
Authors:
Mulichak, AM
Losey, HC
Walsh, CT
Garavito, RM
Citation: Am. Mulichak et al., Structure of the UDP-Glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics, STRUCTURE, 9(7), 2001, pp. 547-557
Authors:
Chiu, HT
Hubbard, BK
Shah, AN
Eide, J
Fredenburg, RA
Walsh, CT
Khosla, C
Citation: Ht. Chiu et al., Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster, P NAS US, 98(15), 2001, pp. 8548-8553
Authors:
Zamble, DB
Miller, DA
Heddle, JG
Maxwell, A
Walsh, CT
Hollfelder, F
Citation: Db. Zamble et al., In vitro characterization of DNA gyrase inhibition by microcin B17 analogswith altered bisheterocyclic sites, P NAS US, 98(14), 2001, pp. 7712-7717
Authors:
Suo, ZC
Tseng, CC
Walsh, CT
Citation: Zc. Suo et al., Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase, P NAS US, 98(1), 2001, pp. 99-104
Authors:
Heddle, JG
Blance, SJ
Zamble, DB
Hollfelder, F
Miller, DA
Wentzell, LM
Walsh, CT
Maxwell, A
Citation: Jg. Heddle et al., The antibiotic microcin B17 is a DNA gyrase poison: Characterisation of the mode of inhibition, J MOL BIOL, 307(5), 2001, pp. 1223-1234
Authors:
Reimmann, C
Patel, HM
Serino, L
Barone, M
Walsh, CT
Haas, D
Citation: C. Reimmann et al., Essential PchG-dependent reduction in pyochelin biosynthesis of Pseudomonas aeruginosa, J BACT, 183(3), 2001, pp. 813-820
Authors:
Chen, HW
Thomas, MG
O'Connor, SE
Hubbard, BK
Burkart, MD
Walsh, CT
Citation: Hw. Chen et al., Aminoacyl-S-enzyme intermediates in beta-hydroxylations and alpha,beta-desaturations of amino acids in peptide antibiotics, BIOCHEM, 40(39), 2001, pp. 11651-11659
Authors:
Marshall, CG
Burkart, MD
Keating, TA
Walsh, CT
Citation: Cg. Marshall et al., Heterocycle formation in vibriobactin biosynthesis: Alternative substrate utilization and identification of a condensed intermediate, BIOCHEM, 40(35), 2001, pp. 10655-10663
Authors:
Patel, HM
Walsh, CT
Citation: Hm. Patel et Ct. Walsh, In vitro reconstitution of the Pseudomonas aeruginosa nonribosomal peptidesynthesis of pyochelin: Characterization of backbone tailoring thiazoline reductase and N-methyltransferase activities, BIOCHEM, 40(30), 2001, pp. 9023-9031
Authors:
Trauger, JW
Kohli, RM
Walsh, CT
Citation: Jw. Trauger et al., Cyclization of backbone-substituted peptides catalyzed by the thioesterasedomain from the tyrocidine nonribosomal peptide synthetase, BIOCHEM, 40(24), 2001, pp. 7092-7098
Authors:
Kohli, RM
Trauger, JW
Schwarzer, D
Marahiel, MA
Walsh, CT
Citation: Rm. Kohli et al., Generality of peptide cyclization catalyzed by isolated thioesterase domains of nonribosomal peptide synthetases, BIOCHEM, 40(24), 2001, pp. 7099-7108
Authors:
Admiraal, SJ
Walsh, CT
Khosla, C
Citation: Sj. Admiraal et al., The loading module of rifamycin synthetase is an adenylation-thiolation didomain with substrate tolerance for substituted benzoates, BIOCHEM, 40(20), 2001, pp. 6116-6123
Authors:
Luo, LS
Walsh, CT
Citation: Ls. Luo et Ct. Walsh, Kinetic analysis of three activated phenylalanyl intermediates generated by the initiation module PheATE of gramicidin S synthetase, BIOCHEM, 40(18), 2001, pp. 5329-5337
Authors:
Miller, DA
Walsh, CT
Citation: Da. Miller et Ct. Walsh, Yersiniabactin synthetase: Probing the recognition of carrier protein domains by the catalytic heterocyclization domains, Cy1 and Cy2, in the chain-initiating HMWP2 subunit, BIOCHEM, 40(17), 2001, pp. 5313-5321
Authors:
Losey, HC
Peczuh, MW
Chen, Z
Eggert, US
Dong, SD
Pelczer, I
Kahne, D
Walsh, CT
Citation: Hc. Losey et al., Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: Novel glycopeptides, BIOCHEM, 40(15), 2001, pp. 4745-4755
Authors:
Yuan, W
Jia, Y
Tian, JM
Snell, KD
Muh, U
Sinskey, AJ
Lambalot, RH
Walsh, CT
Stubbe, J
Citation: W. Yuan et al., Class I and III polyhydroxyalkanoate synthases from Ralstonia eutropha andAllochromatium vinosum: Characterization and substrate specificity studies, ARCH BIOCH, 394(1), 2001, pp. 87-98
Authors:
Luo, LS
Burkart, MD
Stachelhaus, T
Walsh, CT
Citation: Ls. Luo et al., Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase, J AM CHEM S, 123(45), 2001, pp. 11208-11218
Authors:
Miller, DA
Walsh, CT
Luo, LS
Citation: Da. Miller et al., C-methyltransferase and cyclization domain activity at the intraprotein PK/NRP switch point of yersiniabactin synthetase, J AM CHEM S, 123(34), 2001, pp. 8434-8435
Authors:
Healy, VL
Mullins, LS
Li, XF
Hall, SE
Raushel, FM
Walsh, CT
Citation: Vl. Healy et al., D-Ala-D-X ligases: evaluation of D-alanyl phosphate intermediate by MIX, PIX and rapid quench studies, CHEM BIOL, 7(7), 2000, pp. 505-514