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Results: 1-7 |
Results: 7
2-Arylindole-3-acetamides: FPP-competitive inhibitors of farnesyl protein transferase
Authors: Trotter, BW Quigley, AG Lumma, WC Sisko, JT Walsh, ES Hamann, CS Robinson, RG Bhimnathwala, H Kolodin, DG Zheng, W Buser, CA Huber, HE Lobell, RB Kohl, NE Williams, TM Graham, SL Dinsmore, CJ
Citation: Bw. Trotter et al., 2-Arylindole-3-acetamides: FPP-competitive inhibitors of farnesyl protein transferase, BIOORG MED, 11(7), 2001, pp. 865-869
Evaluation of amino acid-based linkers in potent macrocyclic inhibitors offarnesyl-protein transferase
Authors: Beshore, DC Bell, IM Dinsmore, CJ Homnick, CF Culberson, JC Robinson, RG Fernandes, C Walsh, ES Abrams, MT Bhimnathwala, HG Davide, JP Ellis-Hutchings, MS Huber, HA Koblan, KS Buser, CA Kohl, NE Lobell, RB Chen, IW McLoughlin, DA Olah, TV Graham, SL Hartman, GD Williams, TM
Citation: Dc. Beshore et al., Evaluation of amino acid-based linkers in potent macrocyclic inhibitors offarnesyl-protein transferase, BIOORG MED, 11(14), 2001, pp. 1817-1821
Design and biological activity of (S)-4-(5-{[1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino]methyl}imidazol-1-ylmethyl)benzonitrile, a 3-aminopyrrolidinone farnesyltransferase inhibitor with excellent cell potency
Authors: Bell, IM Gallicchio, SN Abrams, M Beshore, DC Buser, CA Culberson, JC Davide, J Ellis-Hutchings, M Fernandes, C Gibbs, JB Graham, SL Hartman, GD Heimbrook, DC Homnick, CF Huff, JR Kassahun, K Koblan, KS Kohl, NE Lobell, RB Lynch, JJ Miller, PA Omer, CA Rodrigues, AD Walsh, ES Williams, TM
Citation: Im. Bell et al., Design and biological activity of (S)-4-(5-{[1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino]methyl}imidazol-1-ylmethyl)benzonitrile, a 3-aminopyrrolidinone farnesyltransferase inhibitor with excellent cell potency, J MED CHEM, 44(18), 2001, pp. 2933-2949
Cloning and characterization of human adenosine 5 '-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2)
Authors: Vulevic, B Chen, ZJ Boyd, JT Davis, W Walsh, ES Belinsky, MG Tew, KD
Citation: B. Vulevic et al., Cloning and characterization of human adenosine 5 '-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2), CANCER RES, 61(8), 2001, pp. 3339-3347
High-performance liquid chromatography/mass spectrometry characterization of Ki4B-Ras in PSN-1 cells treated with the prenyltransferase inhibitor L-778,123
Authors: Buser, CA Dinsmore, CJ Fernandes, C Greenberg, I Hamilton, K Mosser, SD Walsh, ES Williams, TM Koblan, KS
Citation: Ca. Buser et al., High-performance liquid chromatography/mass spectrometry characterization of Ki4B-Ras in PSN-1 cells treated with the prenyltransferase inhibitor L-778,123, ANALYT BIOC, 290(1), 2001, pp. 126-137
Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in mice
Authors: Robledo, RF Buder-Hoffmann, SA Cummins, AB Walsh, ES Taatjes, DJ Mossman, BT
Citation: Rf. Robledo et al., Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in mice, AM J PATH, 156(4), 2000, pp. 1307-1316
Genomic sequence of human glyoxalase-I: analysis of promoter activity and its regulation
Authors: Ranganathan, S Ciaccio, PJ Walsh, ES Tew, KD
Citation: S. Ranganathan et al., Genomic sequence of human glyoxalase-I: analysis of promoter activity and its regulation, GENE, 240(1), 1999, pp. 149-155
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