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Results: 1-25/40
Authors:
Huang, ZQ
Waxman, DJ
Citation: Zq. Huang et Dj. Waxman, Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors, CANC GENE T, 8(6), 2001, pp. 450-458
Authors:
Park, SH
Yamashita, H
Rui, H
Waxman, DJ
Citation: Sh. Park et al., Serine phosphorylation of GH-activated signal transducer and activator of transcription 5a (STAT5a) and STAT5b: Impact on STAT5 transcriptional activity, MOL ENDOCR, 15(12), 2001, pp. 2157-2171
Authors:
Yu, LJ
Matias, J
Scudiero, DA
Hite, KM
Monks, A
Sausville, EA
Waxman, DJ
Citation: Lj. Yu et al., P450 enzyme expression patterns in the NCI human tumor cell line panel, DRUG META D, 29(3), 2001, pp. 304-312
Authors:
Xie, W
Radominska-Pandya, A
Shi, YH
Simon, CM
Nelson, MC
Ong, ES
Waxman, DJ
Evans, RM
Citation: W. Xie et al., An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids, P NAS US, 98(6), 2001, pp. 3375-3380
Authors:
Schwartz, PS
Waxman, DJ
Citation: Ps. Schwartz et Dj. Waxman, Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells, MOLEC PHARM, 60(6), 2001, pp. 1268-1279
Authors:
Li, HC
Liu, DX
Waxman, DJ
Citation: Hc. Li et al., Transcriptional induction of hepatic NADPH: Cytochrome P450 oxidoreductaseby thyroid hormone, MOLEC PHARM, 59(5), 2001, pp. 987-995
Authors:
Park, SH
Waxman, DJ
Citation: Sh. Park et Dj. Waxman, Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3 beta - Impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression, J BIOL CHEM, 276(46), 2001, pp. 43031-43039
Authors:
Davey, HW
Xie, T
McLachlan, MJ
Wilkins, RJ
Waxman, DJ
Grattan, DR
Citation: Hw. Davey et al., STAT5b is required for GH-induced liver Igf-I gene expression, ENDOCRINOL, 142(9), 2001, pp. 3836-3841
Authors:
Tannenbaum, GS
Choi, HK
Gurd, W
Waxman, DJ
Citation: Gs. Tannenbaum et al., Temporal relationship between the sexually dimorphic spontaneous GH secretory profiles and hepatic STAT5 activity, ENDOCRINOL, 142(11), 2001, pp. 4599-4606
Authors:
Jounaidi, Y
Waxman, DJ
Citation: Y. Jounaidi et Dj. Waxman, Frequent, moderate-dose cyclophosphamide administration improves the efficacy of cytochrome P-450/cytochrome P-450 reductase-based cancer gene therapy, CANCER RES, 61(11), 2001, pp. 4437-4444
Authors:
Choi, HK
Waxman, DJ
Citation: Hk. Choi et Dj. Waxman, Pulsatility of growth hormone (GH) signalling in liver cells: role of the JAK-STAT5b pathway in GH action, GROWTH H I, 10, 2000, pp. 1-8
Authors:
Huang, ZQ
Raychowdhury, MK
Waxman, DJ
Citation: Zq. Huang et al., Impact of liver P450 reductase suppression on cyclophosphamide activation,pharmacokinetics and antitumoral activity in a cytochrome P450-based cancer gene therapy model, CANC GENE T, 7(7), 2000, pp. 1034-1042
Authors:
Ram, PK
Waxman, DJ
Citation: Pk. Ram et Dj. Waxman, Role of the cytokine-inducible SH2 protein CIS in desensitization of STAT5b signaling by continuous growth hormone, J BIOL CHEM, 275(50), 2000, pp. 39487-39496
Authors:
Delesque-Touchard, N
Park, SH
Waxman, DJ
Citation: N. Delesque-touchard et al., Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated - STAT5b proposed model for female-specific expression of CYP2C12 in adult rat liver, J BIOL CHEM, 275(44), 2000, pp. 34173-34182
Authors:
Choi, HK
Waxman, DJ
Citation: Hk. Choi et Dj. Waxman, Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: Developmental regulation and role in male-specific liver gene expression, ENDOCRINOL, 141(9), 2000, pp. 3245-3255
Authors:
Dillon, JS
Yaney, GC
Zhou, YC
Voilley, N
Bowen, S
Chipkin, S
Bliss, CR
Schultz, V
Schuit, FC
Prentki, M
Waxman, DJ
Corkey, BE
Citation: Js. Dillon et al., Dehydroepiandrosterone sulfate and beta-cell function - Enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells, DIABETES, 49(12), 2000, pp. 2012-2020
Authors:
Jounaidi, Y
Waxman, DJ
Citation: Y. Jounaidi et Dj. Waxman, Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy, CANCER RES, 60(14), 2000, pp. 3761-3769
Authors:
Huang, ZQ
Roy, P
Waxman, DJ
Citation: Zq. Huang et al., Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide, BIOCH PHARM, 59(8), 2000, pp. 961-972
Authors:
Waxman, DJ
Frank, SJ
Citation: Dj. Waxman et Sj. Frank, Growth hormone action - Signaling via a JAK/STAT-coupled receptor, PRINCIPLES OF MOLECULAR REGULATION, 2000, pp. 55-83
Authors:
Hecht, JED
Waxman, DJ
Citation: Jed. Hecht et Dj. Waxman, Selection of cytochrome P450 genes for use in prodrug activation-based cancer gene therapy, METH MOL M, 35, 2000, pp. 77-83
Authors:
Hecht, JED
Jounaidi, Y
Waxman, DJ
Citation: Jed. Hecht et al., Construction of P450-expressing tumor cell lines using retroviruses, METH MOL M, 35, 2000, pp. 85-94
Authors:
Hecht, JED
Waxman, DJ
Citation: Jed. Hecht et Dj. Waxman, In vitro methods for evaluation of P450-based anticancer gene therapy, METH MOL M, 35, 2000, pp. 95-105
Authors:
Hecht, JED
Schwartz, PS
Waxman, DJ
Citation: Jed. Hecht et al., Tumor models for evaluation of P450 gene therapy in vivo, METH MOL M, 35, 2000, pp. 107-118
Authors:
Gebert, CA
Park, SH
Waxman, DJ
Citation: Ca. Gebert et al., Down-regulation of liver JAK2-STAT5b signaling by the female plasma pattern of continuous growth hormone stimulation, MOL ENDOCR, 13(2), 1999, pp. 213-227
Authors:
Gebert, CA
Park, SH
Waxman, DJ
Citation: Ca. Gebert et al., Termination of growth hormone pulse-induced STAT5b signaling, MOL ENDOCR, 13(1), 1999, pp. 38-56