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Results: 1-25 |
Results: 25
The role of strand 1 of the C beta-sheet in the structure and function of alpha(1)-antitrypsin
Authors: Bottomley, SP Lawrenson, ID Tew, D Dai, WW Whisstock, JC Pike, RN
Citation: Sp. Bottomley et al., The role of strand 1 of the C beta-sheet in the structure and function of alpha(1)-antitrypsin, PROTEIN SCI, 10(12), 2001, pp. 2518-2524
Protein structural alignments and functional genomics
Authors: Irving, JA Whisstock, JC Lesk, AM
Citation: Ja. Irving et al., Protein structural alignments and functional genomics, PROTEINS, 42(3), 2001, pp. 378-382
Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: Identification of a myotubularin-related protein lacking catalytic activity
Authors: Nandurkar, HH Caldwell, KK Whisstock, JC Layton, MJ Gaudet, EA Norris, FA Majerus, PW Mitchell, CA
Citation: Hh. Nandurkar et al., Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: Identification of a myotubularin-related protein lacking catalytic activity, P NAS US, 98(17), 2001, pp. 9499-9504
Mutagenesis of the dengue virus type 2 NS3 proteinase and the production of growth-restricted virus
Authors: Matusan, AE Kelley, PG Pryor, MJ Whisstock, JC Davidson, AD Wright, PJ
Citation: Ae. Matusan et al., Mutagenesis of the dengue virus type 2 NS3 proteinase and the production of growth-restricted virus, J GEN VIROL, 82, 2001, pp. 1647-1656
Characterization and functional analysis of Serp3: a novel myxoma virus-encoded serpin involved in virulence
Authors: Guerin, JL Gelfi, J Camus, C Delverdier, M Whisstock, JC Amardeihl, MF Py, R Bertagnoli, S Messud-Petit, F
Citation: Jl. Guerin et al., Characterization and functional analysis of Serp3: a novel myxoma virus-encoded serpin involved in virulence, J GEN VIROL, 82, 2001, pp. 1407-1417
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins - Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
Authors: Silverman, GA Bird, PI Carrell, RW Church, FC Coughlin, PB Gettins, PGW Irving, JA Lomas, DA Luke, CJ Moyer, RW Pemberton, PA Remold-O'Donnell, E Salvesen, GS Travis, J Whisstock, JC
Citation: Ga. Silverman et al., The serpins are an expanding superfamily of structurally similar but functionally diverse proteins - Evolution, mechanism of inhibition, novel functions, and a revised nomenclature, J BIOL CHEM, 276(36), 2001, pp. 33293-33296
Importance of the P4 ' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop
Authors: Sun, J Whisstock, JC Harriott, P Walker, B Novak, A Thompson, PE Smith, AI Bird, PI
Citation: J. Sun et al., Importance of the P4 ' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop, J BIOL CHEM, 276(18), 2001, pp. 15177-15184
The yeast inositol polyphosphate 5-phosphatase Inp54p localizes to the endoplasmic reticulum via a C-terminal hydrophobic anchoring tail - Regulationof secretion from the endoplasmic
Authors: Wiradjaja, F Ooms, LM Whisstock, JC McColl, B Helfenbaum, L Sambrook, JF Gething, MJ Mitchell, CA
Citation: F. Wiradjaja et al., The yeast inositol polyphosphate 5-phosphatase Inp54p localizes to the endoplasmic reticulum via a C-terminal hydrophobic anchoring tail - Regulationof secretion from the endoplasmic, J BIOL CHEM, 276(10), 2001, pp. 7643-7653
Structure of a serpin-enzyme complex probed by cysteine substitutions and fluorescence spectroscopy
Authors: Ludeman, JP Whisstock, JC Hopkins, PCR Le Bonniec, BF Bottomley, SP
Citation: Jp. Ludeman et al., Structure of a serpin-enzyme complex probed by cysteine substitutions and fluorescence spectroscopy, BIOPHYS J, 80(1), 2001, pp. 491-497
Phylogeny of the serpin superfamily: Implications of patterns of amino acid conservation for structure and function
Authors: Irving, JA Pike, RN Lesk, AM Whisstock, JC
Citation: Ja. Irving et al., Phylogeny of the serpin superfamily: Implications of patterns of amino acid conservation for structure and function, GENOME RES, 10(12), 2000, pp. 1845-1864
Cleaved antitrypsin polymers at atomic resolution
Authors: Dunstone, MA Dai, WW Whisstock, JC Rossjohn, J Pike, RN Feil, SC Le Bonniec, BF Parker, MW Bottomley, SP
Citation: Ma. Dunstone et al., Cleaved antitrypsin polymers at atomic resolution, PROTEIN SCI, 9(2), 2000, pp. 417-420
A single amino acid substitution affects substrate specificity in cysteineproteinases from Fasciola hepatica
Authors: Smooker, PM Whisstock, JC Irving, JA Siyaguna, S Spithill, TW Pike, RN
Citation: Pm. Smooker et al., A single amino acid substitution affects substrate specificity in cysteineproteinases from Fasciola hepatica, PROTEIN SCI, 9(12), 2000, pp. 2567-2572
Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin
Authors: Whisstock, JC Pike, RN Jin, L Skinner, R Pei, XY Carrell, RW Lesk, AM
Citation: Jc. Whisstock et al., Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin, J MOL BIOL, 301(5), 2000, pp. 1287-1305
Conformational changes in serpins: I. The native and cleaved conformationsof alpha(1)-antitrypsin
Authors: Whisstock, JC Skinner, R Carrell, RW Lesk, AM
Citation: Jc. Whisstock et al., Conformational changes in serpins: I. The native and cleaved conformationsof alpha(1)-antitrypsin, J MOL BIOL, 296(2), 2000, pp. 685-699
Conformational changes in serpins: I. The native and cleaved conformationsof alpha(1)-antitrypsin
Authors: Whisstock, JC Skinner, R Carrell, RW Lesk, AM
Citation: Jc. Whisstock et al., Conformational changes in serpins: I. The native and cleaved conformationsof alpha(1)-antitrypsin, J MOL BIOL, 295(3), 2000, pp. 651-665
Prediction of the immunodominant epitope of the pyruvate dehydrogenase complex E2 in primary biliary cirrhosis using phage display
Authors: Rowley, MJ Scealy, M Whisstock, JC Jois, JA Wijeyewickrema, LC Mackay, IR
Citation: Mj. Rowley et al., Prediction of the immunodominant epitope of the pyruvate dehydrogenase complex E2 in primary biliary cirrhosis using phage display, J IMMUNOL, 164(6), 2000, pp. 3413-3419
The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis
Authors: Whisstock, JC Romero, S Gurung, R Nandurkar, H Ooms, LM Bottomley, SP Mitchell, CA
Citation: Jc. Whisstock et al., The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis, J BIOL CHEM, 275(47), 2000, pp. 37055-37061
Requirement of leucine-rich repeats of glycoprotein (GP) Ib alpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex
Authors: Shen, Y Romo, GM Dong, JF Schade, A McIntire, LV Kenny, D Whisstock, JC Berndt, MC Lopez, JA Andrews, RK
Citation: Y. Shen et al., Requirement of leucine-rich repeats of glycoprotein (GP) Ib alpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex, BLOOD, 95(3), 2000, pp. 903-910
Structure and function of the von Willebrand factor A1 domain: analysis with monoclonal antibodies reveals distinct binding sites involved in recognition of the platelet membrane glycoprotein Ib-IX-V complex and ristocetin-dependent activation
Authors: De Luca, M Facey, DA Favaloro, EJ Hertzberg, MS Whisstock, JC McNally, T Andrews, RK Berndt, MC
Citation: M. De Luca et al., Structure and function of the von Willebrand factor A1 domain: analysis with monoclonal antibodies reveals distinct binding sites involved in recognition of the platelet membrane glycoprotein Ib-IX-V complex and ristocetin-dependent activation, BLOOD, 95(1), 2000, pp. 164-172
Simple modifications of the serpin reactive site loop convert SCCA2 into acysteine proteinase inhibitor: A critical role for the P3 ' proline in facilitating RSL cleavage
Authors: Luke, C Schick, C Tsu, C Whisstock, JC Irving, JA Bromme, D Juliano, L Shi, GP Chapman, HA Silverman, GA
Citation: C. Luke et al., Simple modifications of the serpin reactive site loop convert SCCA2 into acysteine proteinase inhibitor: A critical role for the P3 ' proline in facilitating RSL cleavage, BIOCHEM, 39(24), 2000, pp. 7081-7091
SH3 domains in prokaryotes
Authors: Whisstock, JC Lesk, AM
Citation: Jc. Whisstock et Am. Lesk, SH3 domains in prokaryotes, TRENDS BIOC, 24(4), 1999, pp. 132-133
Serpins in the Caenorhabditis elegans genome
Authors: Whisstock, JC Irving, JA Bottomley, SP Pike, RN Lesk, AM
Citation: Jc. Whisstock et al., Serpins in the Caenorhabditis elegans genome, PROTEINS, 36(1), 1999, pp. 31-41
Probing the unfolding pathway of alpha(1)-antitrypsin
Authors: James, EL Whisstock, JC Gore, MG Bottomley, SP
Citation: El. James et al., Probing the unfolding pathway of alpha(1)-antitrypsin, J BIOL CHEM, 274(14), 1999, pp. 9482-9488
Expression and purification of recombinant human granzyme B from Pichia pastoris
Authors: Sun, JR Bird, CH Buzza, MS McKee, KE Whisstock, JC Bird, PI
Citation: Jr. Sun et al., Expression and purification of recombinant human granzyme B from Pichia pastoris, BIOC BIOP R, 261(2), 1999, pp. 251-255
IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes
Authors: de Veer, MJ Sim, H Whisstock, JC Devenish, RJ Ralph, SJ
Citation: Mj. De Veer et al., IFI60/ISG60/IFIT4, a new member of the human IFI54/IFIT2 family of interferon-stimulated genes, GENOMICS, 54(2), 1998, pp. 267-277
Risultati: 1-25 |