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Results: 1-14 |
Results: 14
X-ray crystal structures of Candida albicans dihydrofolate reductase: Highresolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor
Authors: Whitlow, M Howard, AJ Stewart, D Hardman, KD Chan, JH Baccanari, DP Tansik, RL Hong, JS Kuyper, LF
Citation: M. Whitlow et al., X-ray crystal structures of Candida albicans dihydrofolate reductase: Highresolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor, J MED CHEM, 44(18), 2001, pp. 2928-2932
Design, synthesis, and in vitro biological activity of indole-based factorXa inhibitors
Authors: Arnaiz, DO Zhao, ZS Liang, A Trinh, L Whitlow, M Koovakkat, SK Shaw, KJ
Citation: Do. Arnaiz et al., Design, synthesis, and in vitro biological activity of indole-based factorXa inhibitors, BIOORG MED, 10(9), 2000, pp. 957-961
Design, synthesis, and in vitro biological activity of benzimidazole basedfactor Xa inhibitors
Authors: Zhao, ZS Arnaiz, DO Griedel, B Sakata, S Dallas, JL Whitlow, M Trinh, L Post, J Liang, A Morrissey, MM Shaw, KJ
Citation: Zs. Zhao et al., Design, synthesis, and in vitro biological activity of benzimidazole basedfactor Xa inhibitors, BIOORG MED, 10(9), 2000, pp. 963-966
Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry
Authors: McMillan, K Adler, M Auld, DS Baldwin, JJ Blasko, E Browne, LJ Chelsky, D Davey, D Dolle, RE Eagen, KA Erickson, S Feldman, RI Glaser, CB Mallari, C Morrissey, MM Ohlmeyer, MHJ Pan, CH Parkinson, JF Phillips, GB Polokoff, MA Sigal, NH Vergona, R Whitlow, M Young, TA Devlin, JJ
Citation: K. Mcmillan et al., Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry, P NAS US, 97(4), 2000, pp. 1506-1511
Preparation, characterization, and the crystal structure of the inhibitor ZK-807834 (CI-1031) complexed with factor Xa
Authors: Adler, M Davey, DD Phillips, GB Kim, SH Jancarik, J Rumennik, G Light, DR Whitlow, M
Citation: M. Adler et al., Preparation, characterization, and the crystal structure of the inhibitor ZK-807834 (CI-1031) complexed with factor Xa, BIOCHEM, 39(41), 2000, pp. 12534-12542
Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: A comparison of conjugation chemistries and compounds
Authors: Lee, LS Conover, C Shi, C Whitlow, M Filpula, D
Citation: Ls. Lee et al., Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: A comparison of conjugation chemistries and compounds, BIOCONJ CHE, 10(6), 1999, pp. 973-981
Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin
Authors: Whitlow, M Arnaiz, DO Buckman, BO Davey, DD Griedel, B Guilford, WJ Koovakkat, SK Liang, A Mohan, R Phillips, GB Seto, M Shaw, KJ Xu, W Zhao, ZC Light, DR Morrissey, MM
Citation: M. Whitlow et al., Crystallographic analysis of potent and selective factor Xa inhibitors complexed to bovine trypsin, ACT CRYST D, 55, 1999, pp. 1395-1404
Protein fold analysis of the B30.2-like domain
Authors: Seto, MH Liu, HLC Zajchowski, DA Whitlow, M
Citation: Mh. Seto et al., Protein fold analysis of the B30.2-like domain, PROTEINS, 35(2), 1999, pp. 235-249
Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors
Authors: Guilford, WJ Shaw, KJ Dallas, JL Koovakkat, S Lee, W Liang, A Light, DR McCarrick, MA Whitlow, M Ye, B Morrissey, MM
Citation: Wj. Guilford et al., Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors, J MED CHEM, 42(26), 1999, pp. 5415-5425
Conformations of trypsin-bound amidine inhibitors of blood coagulant factor Xa by double REDOR NMR and MD simulations
Authors: McDowell, LM McCarrick, MA Studelska, DR Guilford, WJ Arnaiz, D Dallas, JL Light, DR Whitlow, M Schaefer, J
Citation: Lm. Mcdowell et al., Conformations of trypsin-bound amidine inhibitors of blood coagulant factor Xa by double REDOR NMR and MD simulations, J MED CHEM, 42(19), 1999, pp. 3910-3918
Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xainhibitors
Authors: Phillips, G Davey, DD Eagen, KA Koovakkat, SE Liang, A Ng, HP Pinkerton, M Trinh, L Whitlow, M Beatty, AM Morrissey, MM
Citation: G. Phillips et al., Design, synthesis, and activity of 2,6-diphenoxypyridine-derived factor Xainhibitors, J MED CHEM, 42(10), 1999, pp. 1749-1756
Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase - Implications for dimer stability and comparison with endothelial nitric-oxide synthase
Authors: Li, HY Raman, CS Glaser, CB Blasko, E Young, TA Parkinson, JF Whitlow, M Poulos, TL
Citation: Hy. Li et al., Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase - Implications for dimer stability and comparison with endothelial nitric-oxide synthase, J BIOL CHEM, 274(30), 1999, pp. 21276-21284
Interaction between terminal complement proteins C5b-7 and anionic phospholipids
Authors: Liu, C Marshall, P Schreibman, I Vu, A Gai, WM Whitlow, M
Citation: C. Liu et al., Interaction between terminal complement proteins C5b-7 and anionic phospholipids, BLOOD, 93(7), 1999, pp. 2297-2301
Single-chain Fv with manifold N-glycans as bifunctional scaffolds for immunomolecules
Authors: Wang, ML Lee, LS Nepomich, A Yang, JD Conover, C Whitlow, M Filpula, D
Citation: Ml. Wang et al., Single-chain Fv with manifold N-glycans as bifunctional scaffolds for immunomolecules, PROTEIN ENG, 11(12), 1998, pp. 1277-1283
Risultati: 1-14 |