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Results: 1-25/26
Authors:
Naimi, E
Duan, WL
Wiebe, LI
Knaus, EE
Citation: E. Naimi et al., Synthesis of unnatural 7-substituted-1-(2-deoxy-beta-D-ribofuranosyl)isocarbostyrils: "Thymine replacement" analogs of deoxythymidine for evaluation as antiviral and anticancer agents, NUCLEOS NUC, 20(8), 2001, pp. 1533-1553
Authors:
Wang, ZX
Duan, WL
Wiebe, LI
Balzarini, J
De Clercq, E
Knaus, EE
Citation: Zx. Wang et al., Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzene thymidine mimics, some related alpha-anomers, and their evaluation as antiviral and anticancer agents, NUCLEOS NUC, 20(1-2), 2001, pp. 11-40
Authors:
Wang, ZX
Duan, WL
Wiebe, LI
Balzarini, J
De Clercq, E
Knaus, EE
Citation: Zx. Wang et al., Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzenes: "Thymine replacement" analogs of thymidine for evaluation as anticancer and antiviral agents, NUCLEOS NUC, 20(1-2), 2001, pp. 41-58
Authors:
Machulla, HJ
Wiebe, LI
Mercer, JR
McQuarrie, SA
Citation: Hj. Machulla et al., Proceedings from the International Radiopharmaceutical Education Consortium Workshop - Buhl, Germany, 20-22 July 2000, J PHARM P S, 4(2), 2001, pp. 52-75
Authors:
Naimi, E
Wiebe, LI
Balzarini, J
De Clercq, E
Knaus, EE
Citation: E. Naimi et al., Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-(2-halo-1-hydroxyethyl)benzenes and related derivatives: "Thymine replacement" analogs of deoxythymidine for evaluation as antiviral and anticancer agents, DRUG DEV R, 52(3), 2001, pp. 492-499
Authors:
Stypinski, D
McQuarrie, SA
Wiebe, LI
Tam, YK
Mercer, JR
McEwan, AJB
Citation: D. Stypinski et al., Dosimetry estimations for I-123-IAZA in healthy volunteers, J NUCL MED, 42(9), 2001, pp. 1418-1423
Authors:
Wiebe, LI
Citation: Li. Wiebe, FDG metabolism: Quaecumque sunt vera ... Invited commentary, J NUCL MED, 42(11), 2001, pp. 1679-1681
Authors:
Mark, BL
Parrish, JC
Wang, ZX
Wiebe, LI
Knaus, EE
James, MNG
Citation: Bl. Mark et al., (E)-1-(2 '-Deoxy-beta-D-ribofuranosyl)2,4-difluoro-5-(2-iodovinyl)benzene, ACT CRYST C, 57, 2001, pp. 758-760
Authors:
Kumar, P
Wiebe, LI
Atrazheva, E
Tandon, M
Citation: P. Kumar et al., An improved synthesis of alpha-AZA, alpha-AZP and alpha-AZG, the precursors to clinical markers of tissue hypoxia, TETRAHEDR L, 42(11), 2001, pp. 2077-2078
Authors:
Wang, ZX
Duan, WL
Wiebe, LI
De Clercq, E
Balzarini, J
Knaus, EE
Citation: Zx. Wang et al., Syntheses of 1-[(2-hydroxyethoxy)methyl]- and 1-[(1,3-dihydroxy-2-propoxy)methyl]-derivatives of 5-substituted-2,4-difluorobenzene: Unnatural acyclo thymidine mimics for evaluation as anticancer and antiviral agents, NUCLEOS NUC, 19(9), 2000, pp. 1397-1411
Authors:
Zuo, Z
Kwon, G
Stevenson, B
Diakur, J
Wiebe, LI
Citation: Z. Zuo et al., Flutamide - Hydroxypropyl-beta-cyclodextrin complex: Formulation, physicalcharacterization, and absorption studies using the Caco-2 in vitro model, J PHARM P S, 3(2), 2000, pp. 220-227
Authors:
Lee, HC
Kumar, P
McEwan, AJ
Wiebe, LI
Mercer, JR
Citation: Hc. Lee et al., Synthesis, radiolabeling, and biodistribution of putative metabolites of iodoazomycin arabinoside, NUCL MED BI, 27(1), 2000, pp. 61-68
Authors:
Parang, K
Wiebe, LI
Knaus, EE
Citation: K. Parang et al., Novel approaches for designing 5 '-O-ester prodrugs of 3'-azido-2 ',3 '-dideoxythymidine (AZT), CURR MED CH, 7(10), 2000, pp. 995-1039
Authors:
Morin, KW
Knaus, EE
Wiebe, LI
Xia, H
McEwan, AJB
Citation: Kw. Morin et al., Reporter gene imaging: Effects of ganciclovir treatment on nucleoside uptake, hypoxia and perfusion in a murine gene therapy tumour model that expresses herpes simplex type-1 thymidine kinase, NUCL MED C, 21(2), 2000, pp. 129-137
Authors:
Wang, ZX
Wiebe, LI
Balzarini, J
De Clercq, E
Knaus, EE
Citation: Zx. Wang et al., Chiral synthesis of 4-[1-(2-deoxy-beta-L-ribofuranosyl)] derivatives of 2-substituted 5-fluoroaniline: "Cytosine replacement" analogues of deoxy-beta-L-cytidine, J ORG CHEM, 65(26), 2000, pp. 9214-9219
Authors:
Wang, ZX
Wiebe, LI
De Clercq, E
Balzarini, J
Knaus, EE
Citation: Zx. Wang et al., Syntheses of 4-[1-(2-deoxy-beta-D-ribofuranosyl)]-derivatives of 2-substituted-5-fluoroaniline: '' cytosine replacement '' analogs of deoxycytidine for evaluation as anticancer and antihuman immunodeficiency virus (anti-HIV)agents, CAN J CHEM, 78(8), 2000, pp. 1081-1088
Authors:
Stypinski, D
Wiebe, LI
Tam, YK
Mercer, JR
McEwan, AJB
Citation: D. Stypinski et al., Effects of methoxyflurane anesthesia on the pharmacokinetics of I-125-IAZAin Sprague-Dawley rats, NUCL MED BI, 26(8), 1999, pp. 959-965
Authors:
Lee, HC
Kumar, P
Wiebe, LI
McDonald, R
Mercer, JR
Ohkura, K
Seki, K
Citation: Hc. Lee et al., Synthesis of iodoaminoimidazole arabinoside (IAIA): A potential reductive metabolite of the spect imaging agent, iodoazomycin arabinoside (IAZA), NUCLEOS NUC, 18(9), 1999, pp. 1995-2016
Authors:
Wiebe, LI
Knaus, EE
Morin, KW
Citation: Li. Wiebe et al., Radiolabelled pyrimidine nucleosides to monitor the expression of HSV-1 thymidine kinase in gene therapy, NUCLEOS NUC, 18(4-5), 1999, pp. 1065-1066
Authors:
Diakur, J
Zuo, Z
Wiebe, LI
Citation: J. Diakur et al., Synthesis and drug complexation studies with beta-cyclodextrins fluorinated on the primary face, J CARB CHEM, 18(2), 1999, pp. 209-223
Authors:
Xia, ZP
Wiebe, LI
Miller, GG
Knaus, EE
Citation: Zp. Xia et al., Synthesis and biological evaluation of butanoate, retinoate, and bis(2,2,2-trichloroethyl)phosphate derivatives of 5-fluoro-2 '-deoxyuridine and 2 ',5-difluoro-2 '-deoxyuridine as potential dual action anticancer prodrugs, ARCH PHARM, 332(8), 1999, pp. 286-294
Authors:
Vinjamuri, S
O'Driscoll, K
Maltby, P
McEwan, AJ
Wiebe, LI
Critchley, M
Citation: S. Vinjamuri et al., Identification of hypoxic regions in traumatic brain injury, CLIN NUCL M, 24(11), 1999, pp. 891-892
Authors:
Kumar, P
Stypinski, D
Xia, H
McEwan, AJB
Machulla, HJ
Wiebe, LI
Citation: P. Kumar et al., Fluoroazomycin arabinoside (FAZA): Synthesis, H-2 and H-3-labelling and preliminary biological evaluation of a novel 2-nitroimidazole marker of tissue hypoxia., J LABEL C R, 42(1), 1999, pp. 3-16
Authors:
Wiebe, LI
Knaus, EE
Citation: Li. Wiebe et Ee. Knaus, Concepts for the design of anti-HIV nucleoside prodrugs for treating cephalic HIV infection, ADV DRUG DE, 39(1-3), 1999, pp. 63-80
Authors:
Stypinski, D
Wiebe, LI
McEwan, AJ
Schmidt, RP
Tam, YK
Mercer, JR
Citation: D. Stypinski et al., Clinical pharmacokinetics of I-123-IAZA in healthy volunteers, NUCL MED C, 20(6), 1999, pp. 559-567