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Results: 26-47/47
Authors:
Wittinghofer, A
Citation: A. Wittinghofer, The functioning of molecular switches in three dimensions, FR MOLEC B, 24, 2000, pp. 244-310
Authors:
Hillig, RC
Renault, L
Vetter, IR
Drell, T
Wittinghofer, A
Becker, J
Citation: Rc. Hillig et al., The crystal structure of rna1p: A new fold for a GTPase-activating protein, MOL CELL, 3(6), 1999, pp. 781-791
Authors:
Scheffzek, K
Ahmadian, MR
Wiesmuller, L
Lautwein, A
Kabsch, W
Schmitz, F
Wittinghofer, A
Citation: K. Scheffzek et al., The Ras-RasGAP complex: How to complement an inefficient active site, PHOSPHOR SU, 146, 1999, pp. 741-744
Authors:
Rudolph, MG
Wittinghofer, A
Vetter, IR
Citation: Mg. Rudolph et al., Nucleotide binding to the G12V-mutant of Cdc42 investigated by x-ray diffraction and fluorescence spectroscopy: Two different nucleotide states in one crystal, PROTEIN SCI, 8(4), 1999, pp. 778-787
Authors:
Schelhaas, M
Nagele, E
Kuder, N
Bader, B
Kuhlmann, J
Wittinghofer, A
Waldmann, H
Citation: M. Schelhaas et al., Chemoenzymatic synthesis of biotinylated Ras peptides and their use in membrane binding studies of lipidated model proteins by surface plasmon resonance, CHEM-EUR J, 5(4), 1999, pp. 1239-1252
Authors:
Renault, L
Nassar, N
Wittinghofer, A
Roth, M
Vetter, IR
Citation: L. Renault et al., Crystallization and preliminary X-ray analysis of human RCC1, the regulator of chromosome condensation, ACT CRYST D, 55, 1999, pp. 272-275
Authors:
Ostermann, N
Ahmadian, MR
Wittinghofer, A
Goody, RS
Citation: N. Ostermann et al., New N-2-labelled fluorescent derivatives of guanosine nucleotides and their interaction with GTP-binding proteins, NUCLEOS NUC, 18(2), 1999, pp. 245-262
Authors:
Cool, RH
Schmidt, G
Lenzen, CU
Prinz, H
Vogt, D
Wittinghofer, A
Citation: Rh. Cool et al., The Ras mutant D119N is both dominant negative and activated, MOL CELL B, 19(9), 1999, pp. 6297-6305
Authors:
Herter, P
Kuhnen, C
Muller, KM
Wittinghofer, A
Muller, O
Citation: P. Herter et al., Intracellular distribution of beta-catenin in colorectal adenomas, carcinomas and Peutz-Jeghers polyps, J CANC RES, 125(5), 1999, pp. 297-304
Authors:
Vetter, IR
Arndt, A
Kutay, U
Gorlich, D
Wittinghofer, A
Citation: Ir. Vetter et al., Structural view of the Ran-importin beta interaction at 2.3 angstrom resolution, CELL, 97(5), 1999, pp. 635-646
Authors:
Vetter, IR
Wittinghofer, A
Citation: Ir. Vetter et A. Wittinghofer, Nucleoside triphosphate-binding proteins: different scaffolds to achieve phosphoryl transfer, Q REV BIOPH, 32(1), 1999, pp. 1-56
Authors:
Vetter, IR
Nowak, C
Nishimoto, T
Kuhlmann, J
Wittinghofer, A
Citation: Ir. Vetter et al., Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport, NATURE, 398(6722), 1999, pp. 39-46
Authors:
Ahmadian, MR
Zor, T
Vogt, D
Kabsch, W
Selinger, Z
Wittinghofer, A
Scheffzek, K
Citation: Mr. Ahmadian et al., Guanosine triphosphatase stimulation of oncogenic Ras mutants, P NAS US, 96(12), 1999, pp. 7065-7070
Authors:
Azuma, Y
Renault, L
Garcia-Ranea, JA
Valencia, A
Nishimoto, T
Wittinghofer, A
Citation: Y. Azuma et al., Model of the Ran-RCC1 interaction using biochemical and docking experiments, J MOL BIOL, 289(4), 1999, pp. 1119-1130
Authors:
de Rooij, J
Boenink, NM
van Triest, M
Cool, RH
Wittinghofer, A
Bos, JL
Citation: J. De Rooij et al., PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2, J BIOL CHEM, 274(53), 1999, pp. 38125-38130
Authors:
Bauer, B
Mirey, G
Vetter, IR
Garcia-Ranea, JA
Valencia, A
Wittinghofer, A
Camonis, JH
Cool, RH
Citation: B. Bauer et al., Effector recognition by the small GTP-binding proteins Ras and Ral, J BIOL CHEM, 274(25), 1999, pp. 17763-17770
Authors:
Linnemann, T
Geyer, M
Jaitner, BK
Block, C
Kalbitzer, HR
Wittinghofer, A
Herrmann, C
Citation: T. Linnemann et al., Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily, J BIOL CHEM, 274(19), 1999, pp. 13556-13562
Authors:
van den Berghe, N
Cool, RH
Wittinghofer, A
Citation: N. Van Den Berghe et al., Discriminatory residues in Ras and Rap for guanine nucleotide exchange factor recognition, J BIOL CHEM, 274(16), 1999, pp. 11078-11085
Authors:
Horn, IR
Wittinghofer, A
de Bruine, AP
Hoogenboom, HR
Citation: Ir. Horn et al., Selection of phage-displayed Fab antibodies on the active conformation of Ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras, FEBS LETTER, 463(1-2), 1999, pp. 115-120
Authors:
Vetter, IR
Linnemann, T
Wohlgemuth, S
Geyer, M
Kalbitzer, HR
Herrmann, C
Wittinghofer, A
Citation: Ir. Vetter et al., Structural and biochemical analysis of Ras-effector signaling via RalGDS, FEBS LETTER, 451(2), 1999, pp. 175-180
Authors:
Geyer, M
Assheuer, R
Klebe, C
Kuhlmann, J
Becker, J
Wittinghofer, A
Kalbitzer, HR
Citation: M. Geyer et al., Conformational states of the nuclear GTP-binding protein Ran and its complexes with the exchange factor RCC1 and the effector protein RanBP1, BIOCHEM, 38(35), 1999, pp. 11250-11260
Authors:
de Rooij, J
Zwartkruis, FJT
Verheijen, MHG
Cool, RH
Nijman, SMB
Wittinghofer, A
Bos, JL
Citation: J. De Rooij et al., Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP, NATURE, 396(6710), 1998, pp. 474-477