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Results: 1-9 |
Results: 9
The role of human O-6-alkylguanine-DNA alkyltransferase in promoting 1,2-dibromoethane-induced genotoxicity in Escherichia coli
Authors: Liu, H Xu-Welliver, M Pegg, AE
Citation: H. Liu et al., The role of human O-6-alkylguanine-DNA alkyltransferase in promoting 1,2-dibromoethane-induced genotoxicity in Escherichia coli, MUT RES-F M, 452(1), 2000, pp. 1-10
Point mutations at multiple sites including highly conserved amino acids maintain activity, but render O-6-alkylguanine-DNA alkyltransferase insensitive to O-6-benzylguanine
Authors: Xu-Welliver, M Pegg, AE
Citation: M. Xu-welliver et Ae. Pegg, Point mutations at multiple sites including highly conserved amino acids maintain activity, but render O-6-alkylguanine-DNA alkyltransferase insensitive to O-6-benzylguanine, BIOCHEM J, 347, 2000, pp. 519-526
Conserved residue lysine(165) is essential for the ability of O-6-alkylguanine-DNA alkyltransferase to react with O-6-benzylguanine
Authors: Xu-Welliver, M Kanugula, S Loktionova, NA Crone, TM Pegg, AE
Citation: M. Xu-welliver et al., Conserved residue lysine(165) is essential for the ability of O-6-alkylguanine-DNA alkyltransferase to react with O-6-benzylguanine, BIOCHEM J, 347, 2000, pp. 527-534
Effect of O-6-benzylguanine on alkylating agent-induced toxicity and mutagenicity in Chinese hamster ovary cells expressing wild-type and mutant O-6-alkylguanine-DNA alkyltransferases
Authors: Cai, YN Wu, MH Xu-Welliver, M Pegg, AE Ludeman, SM Dolan, ME
Citation: Yn. Cai et al., Effect of O-6-benzylguanine on alkylating agent-induced toxicity and mutagenicity in Chinese hamster ovary cells expressing wild-type and mutant O-6-alkylguanine-DNA alkyltransferases, CANCER RES, 60(19), 2000, pp. 5464-5469
Direct reversal of DNA damage by mutant methyltransferase protein protectsmice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells
Authors: Ragg, S Xu-Welliver, M Bailey, J D'Souza, M Cooper, R Chandra, S Seshadri, R Pegg, AE Williams, DA
Citation: S. Ragg et al., Direct reversal of DNA damage by mutant methyltransferase protein protectsmice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells, CANCER RES, 60(18), 2000, pp. 5187-5195
Characterization of the P140K, PVP(138-140)MLK, and G156A O-6-methylguanine-DNA methyltransferase mutants: Implications for drug resistance gene therapy
Authors: Davis, BM Roth, JC Liu, LL Xu-Welliver, M Pegg, AE Gerson, SL
Citation: Bm. Davis et al., Characterization of the P140K, PVP(138-140)MLK, and G156A O-6-methylguanine-DNA methyltransferase mutants: Implications for drug resistance gene therapy, HUM GENE TH, 10(17), 1999, pp. 2769-2778
Alteration of the conserved residue tyrosine-158 to histidine renders human O-6-alkylguanine-DNA alkyltransferase insensitive to the inhibitor O-6-benzylguanine
Authors: Xu-Welliver, M Leitao, J Kanugula, S Pegg, AE
Citation: M. Xu-welliver et al., Alteration of the conserved residue tyrosine-158 to histidine renders human O-6-alkylguanine-DNA alkyltransferase insensitive to the inhibitor O-6-benzylguanine, CANCER RES, 59(7), 1999, pp. 1514-1519
Role of codon 160 in the sensitivity of human O-6-alkylguanine-DNA a alkyltransferase to O-6-benzylguanine
Authors: Xu-Welliver, M Leitao, J Kanugula, S Meehan, WJ Pegg, AE
Citation: M. Xu-welliver et al., Role of codon 160 in the sensitivity of human O-6-alkylguanine-DNA a alkyltransferase to O-6-benzylguanine, BIOCH PHARM, 58(8), 1999, pp. 1279-1285
Protection of CHO cells by mutant forms of O(6-)alkylguanine-DNA alkyltransferase from killing by 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) plus O-6-benzylguanine or O-6-benzyl-8-oxoguanine
Authors: Loktionova, NA Xu-Welliver, M Crone, TM Kanugula, S Pegg, AE
Citation: Na. Loktionova et al., Protection of CHO cells by mutant forms of O(6-)alkylguanine-DNA alkyltransferase from killing by 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) plus O-6-benzylguanine or O-6-benzyl-8-oxoguanine, BIOCH PHARM, 58(2), 1999, pp. 237-244
Risultati: 1-9 |