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Results: 1-25 | 26-33
Results: 1-25/33
ADDITIVE EFFECTS OF PS1 AND APP MUTATIONS ON SECRETION OF THE 42-RESIDUE AMYLOID BETA-PROTEIN
Authors: CITRON M ECKMAN CB DIEHL TS CORCORAN C OSTASZEWSKI BL XIA WM LEVESQUE G HYSLOP PS YOUNKIN SG SELKOE DJ
Citation: M. Citron et al., ADDITIVE EFFECTS OF PS1 AND APP MUTATIONS ON SECRETION OF THE 42-RESIDUE AMYLOID BETA-PROTEIN, Neurobiology of disease, 5(2), 1998, pp. 107-116
THE ROLE OF A-BETA-42 IN ALZHEIMERS-DISEASE
Authors: YOUNKIN SG
Citation: Sg. Younkin, THE ROLE OF A-BETA-42 IN ALZHEIMERS-DISEASE, J PHYSL-PAR, 92(3-4), 1998, pp. 289-292
HOT PAPERS - ALZHEIMERS-DISEASE - SECRETED AMYLOID BETA-PROTEIN SIMILAR TO THAT IN THE SENILE PLAQUES OF ALZHEIMERS-DISEASE IS INCREASED IN-VIVO BY THE PRESENILIN-1 AND PRESENILIN-2 AND APP MUTATIONS LINKED TOFAMILIAL ALZHEIMERS-DISEASE BY SCHEUNER,D., ECKMAN,C., JENSEN,M., SONG,X., CITRON,M., SUZUKI,N., BIRD,T.D., HARDY,J., HUTTON,M., KUKULL,W.,LARSON,E., LEVYLAHAD,E., VIITANEN,M., PESKIND,E., POORKAJ,P., SCHELLENBERG,G., TANZI,R., WASCO,W., LANNFELT,L.,
Authors: YOUNKIN SG
Citation: Sg. Younkin, HOT PAPERS - ALZHEIMERS-DISEASE - SECRETED AMYLOID BETA-PROTEIN SIMILAR TO THAT IN THE SENILE PLAQUES OF ALZHEIMERS-DISEASE IS INCREASED IN-VIVO BY THE PRESENILIN-1 AND PRESENILIN-2 AND APP MUTATIONS LINKED TOFAMILIAL ALZHEIMERS-DISEASE BY SCHEUNER,D., ECKMAN,C., JENSEN,M., SONG,X., CITRON,M., SUZUKI,N., BIRD,T.D., HARDY,J., HUTTON,M., KUKULL,W.,LARSON,E., LEVYLAHAD,E., VIITANEN,M., PESKIND,E., POORKAJ,P., SCHELLENBERG,G., TANZI,R., WASCO,W., LANNFELT,L.,, The Scientist, 12(19), 1998, pp. 11-11
PLASMA AMYLOID (A-BETA) LEVELS IN RELATIVES OF ALZHEIMERS-DISEASE PATIENTS
Authors: GRAFFRADFORD NR ECKMAN C HUTTON ML OBRIEN PC PEREZTUR J YOUNKIN SG
Citation: Nr. Graffradford et al., PLASMA AMYLOID (A-BETA) LEVELS IN RELATIVES OF ALZHEIMERS-DISEASE PATIENTS, Neurology, 50(4), 1998, pp. 33005-33005
ALTERED METABOLISM OF FAMILIAL ALZHEIMERS-DISEASE-LINKED AMYLOID PRECURSOR PROTEIN VARIANTS IN YEAST ARTIFICIAL CHROMOSOME TRANSGENIC MICE
Authors: LAMB BT CALL LM SLUNT HH BARDEL KA LAWLER AM ECKMAN CB YOUNKIN SG HOLTZ G WAGNER SL PRICE DL SISODIA SS GEARHART JD
Citation: Bt. Lamb et al., ALTERED METABOLISM OF FAMILIAL ALZHEIMERS-DISEASE-LINKED AMYLOID PRECURSOR PROTEIN VARIANTS IN YEAST ARTIFICIAL CHROMOSOME TRANSGENIC MICE, Human molecular genetics, 6(9), 1997, pp. 1535-1541
A NEW PATHOGENIC MUTATION IN THE APP GENE (1716V) INCREASES THE RELATIVE PROPORTION OF A-BETA-42(43)
Authors: ECKMAN CB MEHTA ND CROOK R PEREZTUR J PRIHAR G PFEIFFER E GRAFFRADFORD N HINDER P YAGER D ZENK B REFOLO LM PRADA CM YOUNKIN SG HUTTON M HARDY J
Citation: Cb. Eckman et al., A NEW PATHOGENIC MUTATION IN THE APP GENE (1716V) INCREASES THE RELATIVE PROPORTION OF A-BETA-42(43), Human molecular genetics, 6(12), 1997, pp. 2087-2089
GENETIC-MODIFICATION OF THE PHENOTYPES PRODUCED BY AMYLOID PRECURSOR PROTEIN OVEREXPRESSION IN TRANSGENIC MICE
Authors: CARLSON GA BORCHELT DR DAKE A TURNER S DANIELSON V COFFIN JD ECKMAN C MEINERS J NILSEN SP YOUNKIN SG HSIAO KK
Citation: Ga. Carlson et al., GENETIC-MODIFICATION OF THE PHENOTYPES PRODUCED BY AMYLOID PRECURSOR PROTEIN OVEREXPRESSION IN TRANSGENIC MICE, Human molecular genetics, 6(11), 1997, pp. 1951-1959
PLASMA AMYLOID-BETA PROTEIN (A-BETA) IN DOWNS-SYNDROME (DS) - IMPLICATIONS FOR ALZHEIMERS-DISEASE (AD)
Authors: GRAFFRADFORD NR ECKMAN CB OBRIEN PC YOUNKIN SG
Citation: Nr. Graffradford et al., PLASMA AMYLOID-BETA PROTEIN (A-BETA) IN DOWNS-SYNDROME (DS) - IMPLICATIONS FOR ALZHEIMERS-DISEASE (AD), Neurology, 48(3), 1997, pp. 63005-63005
METABOLISM AND FUNCTION OF PRESENILIN-1
Authors: SISODIA SS THINAKARAN G BORCHELT DR LEE MK DOAN A WONG P ZHENG H ECKMAN C SLUNT HH VANDERPLOEG LHT YOUNKIN SG JENKINS NA COPELAND NG PRICE DL
Citation: Ss. Sisodia et al., METABOLISM AND FUNCTION OF PRESENILIN-1, Journal of neurochemistry, 69, 1997, pp. 5-5
NEURONAL EXPRESSION OF BETA-AMYLOID PRECURSOR PROTEIN ALZHEIMER MUTATIONS CAUSES INTRACELLULAR ACCUMULATION OF A C-TERMINAL FRAGMENT CONTAINING BOTH THE AMYLOID-BETA AND CYTOPLASMIC DOMAINS
Authors: MCPHIE DL LEE RKK ECKMAN CB OLSTEIN DH DURHAM SP YAGER D YOUNKIN SG WURTMAN RJ NEVE RL
Citation: Dl. Mcphie et al., NEURONAL EXPRESSION OF BETA-AMYLOID PRECURSOR PROTEIN ALZHEIMER MUTATIONS CAUSES INTRACELLULAR ACCUMULATION OF A C-TERMINAL FRAGMENT CONTAINING BOTH THE AMYLOID-BETA AND CYTOPLASMIC DOMAINS, The Journal of biological chemistry, 272(40), 1997, pp. 24743-24746
FAMILIAL ALZHEIMERS-DISEASE-LINKED PRESENILIN-1 VARIANTS ELEVATE A-BETA-1-42 1-40 RATIO IN-VITRO AND IN-VIVO/
Authors: BORCHELT DR THINAKARAN G ECKMAN CB LEE MK DAVENPORT F RATOVITSKY T PRADA CM KIM G SEEKINS S YAGER D SLUNT HH WANG R SEEGER M LEVEY AI GANDY SE COPELAND NG JENKINS NA PRICE DL YOUNKIN SG
Citation: Dr. Borchelt et al., FAMILIAL ALZHEIMERS-DISEASE-LINKED PRESENILIN-1 VARIANTS ELEVATE A-BETA-1-42 1-40 RATIO IN-VITRO AND IN-VIVO/, Neuron, 17(5), 1996, pp. 1005-1013
ACCUMULATION OF BETA-AMYLOID FIBRILS IN PANCREAS OF TRANSGENIC MICE (VOL 17, PG 215, 1996)
Authors: KAWARABAYASHI T SHOJI M SATO M SASAKI A HO L ECKMAN CB PRADA CM YOUNKIN SG KOBAYASHI T TADA N MATSUBARA E IIZUKA T HARIGAYA Y KASAI K HIRAI S
Citation: T. Kawarabayashi et al., ACCUMULATION OF BETA-AMYLOID FIBRILS IN PANCREAS OF TRANSGENIC MICE (VOL 17, PG 215, 1996), Neurobiology of aging, 17(4), 1996, pp. 667-667
ACCUMULATION OF BETA-AMYLOID FIBRILS IN PANCREAS OF TRANSGENIC MICE
Authors: KAWARABAYASHI T SHOJI M SATO M SASAKI A HO LB ECKMAN CB PRADA CM YOUNKIN SG KOBAYASHI T TADA N MATSUBARA E IIZUKA T HARIGAYA Y KASAI K HIRAI S
Citation: T. Kawarabayashi et al., ACCUMULATION OF BETA-AMYLOID FIBRILS IN PANCREAS OF TRANSGENIC MICE, Neurobiology of aging, 17(2), 1996, pp. 215-222
AMYLOID-BETA PROTEIN IN PLASMA OF ALZHEIMERS-DISEASE PATIENTS AND CONTROLS
Authors: GRAFFRADFORD NR ECKMAN CB YOUNKIN SG
Citation: Nr. Graffradford et al., AMYLOID-BETA PROTEIN IN PLASMA OF ALZHEIMERS-DISEASE PATIENTS AND CONTROLS, Neurology, 46(2), 1996, pp. 5002-5002
THE ALTERNATIVELY SPLICED KUNITZ PROTEASE INHIBITOR DOMAIN ALTERS AMYLOID-BETA PROTEIN-PRECURSOR PROCESSING AND AMYLOID-BETA PROTEIN-PRODUCTION IN CULTURED-CELLS
Authors: HO LB FUKUCHI K YOUNKIN SG
Citation: Lb. Ho et al., THE ALTERNATIVELY SPLICED KUNITZ PROTEASE INHIBITOR DOMAIN ALTERS AMYLOID-BETA PROTEIN-PRECURSOR PROCESSING AND AMYLOID-BETA PROTEIN-PRODUCTION IN CULTURED-CELLS, The Journal of biological chemistry, 271(48), 1996, pp. 30929-30934
AMYLOIDS BETA(40) AND BETA(42) ARE GENERATED INTRACELLULARLY IN CULTURED HUMAN NEURONS AND THEIR SECRETION INCREASES WITH MATURATION
Authors: TURNER RS SUZUKI N CHYUNG ASC YOUNKIN SG LEE VMY
Citation: Rs. Turner et al., AMYLOIDS BETA(40) AND BETA(42) ARE GENERATED INTRACELLULARLY IN CULTURED HUMAN NEURONS AND THEIR SECRETION INCREASES WITH MATURATION, The Journal of biological chemistry, 271(15), 1996, pp. 8966-8970
THE EFFECT OF AMYLOID PRECURSOR PROTEIN AND PRESENILIN MUTATIONS ON AMYLOID-BETA PROTEIN
Authors: YOUNKIN SG SONG XH SCHEUNER D ECKMAN C PRADA CM JENSEN J LANNFELT L HARDY J TANZI R SCHELLENBERG G SELKOE D SUZUKI N
Citation: Sg. Younkin et al., THE EFFECT OF AMYLOID PRECURSOR PROTEIN AND PRESENILIN MUTATIONS ON AMYLOID-BETA PROTEIN, Biological psychiatry, 39(7), 1996, pp. 216-216
HIGH-LEVELS OF CIRCULATING BETA-AMYLOID PEPTIDE DO NOT CAUSE CEREBRALBETA-AMYLOIDOSIS IN TRANSGENIC MICE
Authors: FUKUCHI K HO LB YOUNKIN SG KUNKEL DD OGBURN CE LEBOEUF RC FURLONG CE DEEB SS NOCHLIN D WEGIEL J WISNIEWSKI HM MARTIN GM
Citation: K. Fukuchi et al., HIGH-LEVELS OF CIRCULATING BETA-AMYLOID PEPTIDE DO NOT CAUSE CEREBRALBETA-AMYLOIDOSIS IN TRANSGENIC MICE, The American journal of pathology, 149(1), 1996, pp. 219-227
EVIDENCE THAT A-BETA-42 IS THE REAL CULPRIT IN ALZHEIMERS-DISEASE
Authors: YOUNKIN SG
Citation: Sg. Younkin, EVIDENCE THAT A-BETA-42 IS THE REAL CULPRIT IN ALZHEIMERS-DISEASE, Annals of neurology, 37(3), 1995, pp. 287-288
AMYLOID-BETA PROTEIN (A-BETA) REMOVAL BY NEUROGLIAL CELLS IN CULTURE
Authors: SHAFFER LM DORITY MD GUPTABANSAL R FREDERICKSON RCA YOUNKIN SG BRUNDEN KR
Citation: Lm. Shaffer et al., AMYLOID-BETA PROTEIN (A-BETA) REMOVAL BY NEUROGLIAL CELLS IN CULTURE, Neurobiology of aging, 16(5), 1995, pp. 737-745
THE DELTA-NL ALZHEIMER MUTATION (SWEDISH) INCREASES PLASMA AMYLOID-BETA PROTEIN-CONCENTRATION
Authors: SONG XH JENSEN M SUZUKI N LANNFELT L YOUNKIN SG
Citation: Xh. Song et al., THE DELTA-NL ALZHEIMER MUTATION (SWEDISH) INCREASES PLASMA AMYLOID-BETA PROTEIN-CONCENTRATION, Journal of neuropathology and experimental neurology, 54(3), 1995, pp. 412-412
THE DELTA-NL ALZHEIMER MUTATION (SWEDISH) INCREASES PLASMA AMYLOID-BETA PROTEIN-CONCENTRATION
Authors: JENSEN M SONG XH SUZUKI N LANNFELT L YOUNKIN SG
Citation: M. Jensen et al., THE DELTA-NL ALZHEIMER MUTATION (SWEDISH) INCREASES PLASMA AMYLOID-BETA PROTEIN-CONCENTRATION, Journal of neurochemistry, 65, 1995, pp. 136-136
AMYLOID-BETA PROTEIN (A-BETA) IN ALZHEIMERS-DISEASE BRAIN - BIOCHEMICAL AND IMMUNOCYTOCHEMICAL ANALYSIS WITH ANTIBODIES SPECIFIC FOR FORMS ENDING AT A-BETA-40 OR A-BETA-42(43)
Authors: GRAVINA SA HO LB ECKMAN CB LONG KE OTVOS L YOUNKIN LH SUZUKI N YOUNKIN SG
Citation: Sa. Gravina et al., AMYLOID-BETA PROTEIN (A-BETA) IN ALZHEIMERS-DISEASE BRAIN - BIOCHEMICAL AND IMMUNOCYTOCHEMICAL ANALYSIS WITH ANTIBODIES SPECIFIC FOR FORMS ENDING AT A-BETA-40 OR A-BETA-42(43), The Journal of biological chemistry, 270(13), 1995, pp. 7013-7016
PROCESSING OF THE ALZHEIMER AMYLOID PROTEIN PRECURSORS
Authors: GOLDE TE CAI XD CHEUNG TT YOUNKIN SG
Citation: Te. Golde et al., PROCESSING OF THE ALZHEIMER AMYLOID PROTEIN PRECURSORS, Journal of cellular biochemistry, 1994, pp. 126-126
AMYLOID-BETA PROTEIN-LEVELS IN CEREBROSPINAL-FLUID ARE ELEVATED IN EARLY-ONSET ALZHEIMERS-DISEASE
Authors: NAKAMURA T SHOJI M HARIGAYA Y WATANABE M HOSODA K CHEUNG TT SHAFFER LM GOLDE TE YOUNKIN LH YOUNKIN SG HIRAI S
Citation: T. Nakamura et al., AMYLOID-BETA PROTEIN-LEVELS IN CEREBROSPINAL-FLUID ARE ELEVATED IN EARLY-ONSET ALZHEIMERS-DISEASE, Annals of neurology, 36(6), 1994, pp. 903-911
Risultati: 1-25 | 26-33