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Results:
1-8
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Results: 8
Authors:
Chauret, N
Yergey, JA
Brideau, C
Friesen, RW
Mancini, J
Riendeau, D
Silva, J
Styhler, A
Trimble, LA
Nicoll-Griffith, DA
Citation: N. Chauret et al., In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663), BIOORG MED, 11(8), 2001, pp. 1059-1062
In vitro metabolism of the Cox-2 inhibitor DFU, including a novel glutathione adduct rearomatization
Authors:
Yergey, JA
Trimble, LA
Silva, J
Chauret, N
Li, C
Therien, M
Grimm, E
Nicoll-Griffith, DA
Citation: Ja. Yergey et al., In vitro metabolism of the Cox-2 inhibitor DFU, including a novel glutathione adduct rearomatization, DRUG META D, 29(5), 2001, pp. 638-644
Authors:
Li, C
Chauret, N
Trimble, LA
Nicoll-Griffith, DA
Silva, JM
Macdonald, D
Perrier, H
Yergey, JA
Parton, T
Alexander, RP
Warrellow, GJ
Citation: C. Li et al., Investigation of the in vitro metabolism profile of a phosphodiesterase-IVinhibitor, CDP-840: Leading to structural optimization, DRUG META D, 29(3), 2001, pp. 232-241
Authors:
Nicoll-Griffith, DA
Silva, JM
Chauret, N
Day, S
Leblanc, Y
Roy, P
Yergey, JA
Dixit, R
Patrick, D
Citation: Da. Nicoll-griffith et al., Application of rat hepatocyte culture to predict in vivo metabolic auto-induction: Studies with DFP, a cyclooxygenase-2 inhibitor, DRUG META D, 29(2), 2001, pp. 159-165
Authors:
Nicoll-Griffith, DA
Yergey, JA
Trimble, LA
Silva, JM
Li, C
Chauret, N
Gauthier, JY
Grimm, E
Leger, S
Roy, P
Therien, M
Wang, ZY
Prasit, P
Zamboni, R
Young, RN
Brideau, C
Chan, CC
Mancini, J
Riendeau, D
Citation: Da. Nicoll-griffith et al., Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx (TM)), BIOORG MED, 10(23), 2000, pp. 2683-2686
Authors:
Li, C
McClory, A
Wong, E
Yergey, JA
Citation: C. Li et al., Mass spectrometric analysis of arachidonyl-containing phospholipids in human U937 cells, J MASS SPEC, 34(5), 1999, pp. 521-536
Authors:
Nicoll-Griffith, DA
Falgueyret, JP
Silva, JM
Morin, PE
Trimble, L
Chan, CC
Clas, S
Leger, S
Wang, ZY
Yergey, JA
Riendeau, D
Citation: Da. Nicoll-griffith et al., Oxidative bioactivation of the lactol prodrug of a lactone cyclooxygenase-2 inhibitor, DRUG META D, 27(3), 1999, pp. 403-409
Authors:
Chauret, N
Tremblay, N
Lackman, RL
Gauthier, JY
Silva, JM
Marois, J
Yergey, JA
Nicoll-Griffith, DA
Citation: N. Chauret et al., Description of a 96-well plate assay to measure cytochrome P4503A inhibition in human liver microsomes using a selective fluorescent probe, ANALYT BIOC, 276(2), 1999, pp. 215-226
Risultati:
1-8
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