Authors:
Hagen, SE
Domagala, J
Gajda, C
Lovdahl, M
Tait, BD
Wise, E
Holler, T
Hupe, D
Nouhan, C
Urumov, A
Zeikus, G
Zeikus, E
Lunney, EA
Pavlovsky, A
Gracheck, SJ
Saunders, J
VanderRoest, S
Brodfuehrer, J
Citation: Se. Hagen et al., 4-hydroxy-5,6-dihydropyrones as inhibitors of HIV protease: The effect of heterocyclic substituents at C-6 on antiviral potency and pharmacokinetic parameters, J MED CHEM, 44(14), 2001, pp. 2319-2332
Authors:
Boyer, FE
Prasad, JVNV
Domagala, JM
Ellsworth, EL
Gajda, C
Hagen, SE
Markoski, LJ
Tait, BD
Lunney, EA
Palovsky, A
Ferguson, D
Graham, N
Holler, T
Hupe, D
Nouhan, C
Tummino, PJ
Urumov, A
Zeikus, E
Zeikus, G
Gracheck, SJ
Sanders, JM
VanderRoest, S
Brodfuehrer, J
Iyer, K
Sinz, M
Gulnik, SV
Erickson, JW
Citation: Fe. Boyer et al., 5,6-dihydropyran-2-ones possessing various sulfonyl functionalities: Potent nonpeptidic inhibitors of HIV protease, J MED CHEM, 43(5), 2000, pp. 843-858
Authors:
Prasad, JVNV
Boyer, FE
Domagala, JM
Ellsworth, EL
Gajda, C
Hamilton, HW
Hagen, SE
Markoski, LJ
Steinbaugh, BA
Tait, BD
Humblet, C
Lunney, EA
Pavlovsky, A
Rubin, JR
Ferguson, D
Graham, N
Holler, T
Hupe, D
Nouhan, C
Tummino, PJ
Urumov, A
Zeikus, E
Zeikus, G
Gracheck, SJ
Saunders, JM
VanderRoest, S
Brodfuehrer, J
Iyer, K
Sinz, M
Gulnik, SV
Erickson, JW
Citation: Jvnv. Prasad et al., Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390: A lead HIV protease inhibitor, BIO MED CH, 7(12), 1999, pp. 2775-2800
Authors:
Ellsworth, EL
Domagala, J
Prasad, JVNV
Hagen, S
Ferguson, D
Holler, T
Hupe, D
Graham, N
Nouhan, C
Tummino, PJ
Zeikus, G
Lunney, EA
Citation: El. Ellsworth et al., 4-Hydroxy-5,6-dihydro-2H-pyran-2-ones. 3. Bicyclic and heteroaromatic ringsystems as 3-position scaffolds to bind to S-1 ' and S-2 ' of the HIV-1 protease enzyme., BIOORG MED, 9(14), 1999, pp. 2019-2024