Authors: Perrin, D Gras, S van Hille, B Hill, BT

Citation: D. Perrin et al., Expression in yeast and purification of functional recombinant human poly(ADP-ribose)polymerase (PARP). Comparative pharmacological profile with thatof the rat enzyme, J ENZ INHIB, 15(5), 2000, pp. 461-469

Authors: van Hille, B Etievant, C Barret, JM Kruczynski, A Hill, BT

Citation: B. Van Hille et al., Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action, ANTI-CANC D, 11(10), 2000, pp. 829-841

Authors: Etievant, C Kruczynski, A Barret, JM Perrin, D van Hille, B Guminski, Y Hill, BT

Citation: C. Etievant et al., F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103, CANC CHEMOT, 46(2), 2000, pp. 101-113

Authors: Perrin, D van Hille, B Barret, JM Kruczynski, A Etievant, C Imbert, T Hill, BT

Citation: D. Perrin et al., F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action, BIOCH PHARM, 59(7), 2000, pp. 807-819

Authors: van Hille, B Perrin, D Hill, BT

Citation: B. Van Hille et al., Differential in vitro interactions of a series of clinically useful topoisomerase-interacting compounds with the cleavage/religation activity of the human topoisomerase II alpha and II beta isoforms, ANTI-CANC D, 10(6), 1999, pp. 551-560

Authors: van Hille, B Clerc, X Creighton, AM Hill, BT

Citation: B. Van Hille et al., Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds, BR J CANC, 81(5), 1999, pp. 800-807