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Results: 1-25 | 26-39
Results: 1-25/39
Drug interactions with grapefruit juice: An update
Authors: Greenblatt, DJ Patki, KC von Moltke, LL Shader, RI
Citation: Dj. Greenblatt et al., Drug interactions with grapefruit juice: An update, J CL PSYCH, 21(4), 2001, pp. 357-359
Drug transporters revisited
Authors: von Moltke, LL Greenblatt, DJ
Citation: Ll. Von Moltke et Dj. Greenblatt, Drug transporters revisited, J CL PSYCH, 21(1), 2001, pp. 1-3
Human drug metabolism and the cytochromes P450: Application and relevance of in vitro models
Authors: Venkatakrishnan, K von Moltke, LL Greenblatt, DJ
Citation: K. Venkatakrishnan et al., Human drug metabolism and the cytochromes P450: Application and relevance of in vitro models, J CLIN PHAR, 41(11), 2001, pp. 1149-1179
Relative contribution of CYP3A to amitriptyline clearance in humans: In vitro and in vivo studies
Authors: Venkatakrishnan, K Schmider, J Harmatz, JS Ehrenberg, BL von Moltke, LL Graf, JA Mertzanis, P Corbett, KE Rodriguez, MC Shader, RI Greenblatt, DJ
Citation: K. Venkatakrishnan et al., Relative contribution of CYP3A to amitriptyline clearance in humans: In vitro and in vivo studies, J CLIN PHAR, 41(10), 2001, pp. 1043-1054
Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors
Authors: von Moltke, LL Greenblatt, DJ Granda, BW Giancarlo, GM Duan, SX Daily, JP Harmatz, JS Shader, RI
Citation: Ll. Von Moltke et al., Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors, J CLIN PHAR, 41(1), 2001, pp. 85-91
Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: Potential drug interactions with bupropion
Authors: Hesse, LM von Moltke, LL Shader, RI Greenblatt, DJ
Citation: Lm. Hesse et al., Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: Potential drug interactions with bupropion, DRUG META D, 29(2), 2001, pp. 100-102
Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine
Authors: Giancarlo, GM Venkatakrishnan, K Granda, BW von Moltke, LL Greenblatt, DJ
Citation: Gm. Giancarlo et al., Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine, EUR J CL PH, 57(1), 2001, pp. 31-36
Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line
Authors: Perloff, MD von Moltke, LL Marchand, JE Greenblatt, DJ
Citation: Md. Perloff et al., Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line, J PHARM SCI, 90(11), 2001, pp. 1829-1837
Differential impairment of triazolam and zolpidem clearance by ritonavir
Authors: Greenblatt, DJ von Moltke, LL Harmatz, JS Durol, ALB Daily, JP Graf, JA Mertzanis, P Hoffman, JL Shader, RI
Citation: Dj. Greenblatt et al., Differential impairment of triazolam and zolpidem clearance by ritonavir, J ACQ IMM D, 24(2), 2000, pp. 129-136
Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level
Authors: Cotreau, MM von Moltke, LL Beinfeld, MC Greenblatt, DJ
Citation: Mm. Cotreau et al., Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level, J PHARM TOX, 43(1), 2000, pp. 41-54
Effects of the antifungal agents on oxidative drug metabolism - Clinical relevance
Authors: Venkatakrishnan, K von Moltke, LL Greenblatt, DJ
Citation: K. Venkatakrishnan et al., Effects of the antifungal agents on oxidative drug metabolism - Clinical relevance, CLIN PHARMA, 38(2), 2000, pp. 111-180
Drug transporters in psychopharmacology - Are they important?
Authors: von Moltke, LL Greenblatt, DJ
Citation: Ll. Von Moltke et Dj. Greenblatt, Drug transporters in psychopharmacology - Are they important?, J CL PSYCH, 20(3), 2000, pp. 291-294
Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture
Authors: Perloff, MD von Moltke, LL Fahey, JM Daily, JP Greenblatt, DJ
Citation: Md. Perloff et al., Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture, AIDS, 14(9), 2000, pp. 1287-1289
Unusually low clearance of two CYP3A substrates, alprazolam and trazodone,in a volunteer subject with wild-type CYP3A4 promoter region
Authors: von Moltke, LL Tran, TH Cotreau, MM Greenblatt, DJ
Citation: Ll. Von Moltke et al., Unusually low clearance of two CYP3A substrates, alprazolam and trazodone,in a volunteer subject with wild-type CYP3A4 promoter region, J CLIN PHAR, 40(2), 2000, pp. 200-204
In vitro biotransformation of sildenafil (Viagra): Identification of humancytochromes and potential drug interactions
Authors: Warrington, JS Shader, RI von Moltke, LL Greenblatt, DJ
Citation: Js. Warrington et al., In vitro biotransformation of sildenafil (Viagra): Identification of humancytochromes and potential drug interactions, DRUG META D, 28(4), 2000, pp. 392-397
Kinetics and dynamics of lorazepam during and after continuous intravenousinfusion
Authors: Greenblatt, DJ von Moltke, LL Ehrenberg, BL Harmatz, JS Corbett, KE Wallace, DW Shader, RI
Citation: Dj. Greenblatt et al., Kinetics and dynamics of lorazepam during and after continuous intravenousinfusion, CRIT CARE M, 28(8), 2000, pp. 2750-2757
Potent mechanism-based inhibition of human CYP3A in vitro by amprenavir and ritonavir: comparison with ketoconazole
Authors: von Moltke, LL Durol, ALB Duan, SX Greenblatt, DJ
Citation: Ll. Von Moltke et al., Potent mechanism-based inhibition of human CYP3A in vitro by amprenavir and ritonavir: comparison with ketoconazole, EUR J CL PH, 56(3), 2000, pp. 259-261
Scaling drug biotransformation data from cDNA-expressed cytochrome P-450 to human liver: A comparison of relative activity factors and human liver abundance in studies of mirtazapine metabolism
Authors: Stormer, ES von Moltke, LL Greenblatt, DJ
Citation: Es. Stormer et al., Scaling drug biotransformation data from cDNA-expressed cytochrome P-450 to human liver: A comparison of relative activity factors and human liver abundance in studies of mirtazapine metabolism, J PHARM EXP, 295(2), 2000, pp. 793-801
Microsomal binding of amitriptyline: Effect on estimation of enzyme kinetic parameters in vitro
Authors: Venkatakrishnan, K von Moltke, LL Obach, RS Greenblatt, DJ
Citation: K. Venkatakrishnan et al., Microsomal binding of amitriptyline: Effect on estimation of enzyme kinetic parameters in vitro, J PHARM EXP, 293(2), 2000, pp. 343-350
Comparative kinetics and response to the benzodiazepine agonists triazolamand zolpidem: Evaluation of sex-dependent differences
Authors: Greenblatt, DJ Harmatz, JS von Moltke, LL Wright, CE Durol, ALB Harrel-Joseph, LM Shader, RI
Citation: Dj. Greenblatt et al., Comparative kinetics and response to the benzodiazepine agonists triazolamand zolpidem: Evaluation of sex-dependent differences, J PHARM EXP, 293(2), 2000, pp. 435-443
Midazolam and triazolam biotransformation in mouse and human liver microsomes: Relative contribution of CYP3A and CYP2C isoforms
Authors: Perloff, MD von Moltke, LL Court, MH Kotegawa, T Shader, RI Greenblatt, DJ
Citation: Md. Perloff et al., Midazolam and triazolam biotransformation in mouse and human liver microsomes: Relative contribution of CYP3A and CYP2C isoforms, J PHARM EXP, 292(2), 2000, pp. 618-628
Alprazolam-ritonavir interaction: Implications for product labeling
Authors: Greenblatt, DJ von Moltke, LL Harmatz, JS Durol, ALB Daily, JP Graf, JA Mertzanis, P Hoffman, JL Shader, RI
Citation: Dj. Greenblatt et al., Alprazolam-ritonavir interaction: Implications for product labeling, CLIN PHARM, 67(4), 2000, pp. 335-341
In vitro metabolism of trazodone by CYP3A: Inhibition by ketoconazole and human immunodeficiency viral protease inhibitors
Authors: Zalma, A von Moltke, LL Granda, BW Harmatz, JS Shader, RI Greenblatt, DJ
Citation: A. Zalma et al., In vitro metabolism of trazodone by CYP3A: Inhibition by ketoconazole and human immunodeficiency viral protease inhibitors, BIOL PSYCHI, 47(7), 2000, pp. 655-661
Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions
Authors: von Moltke, LL Greenblatt, DJ Granda, BW Grassi, JM Schmider, J Harmatz, JS Shader, RI
Citation: Ll. Von Moltke et al., Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions, PSYCHOPHAR, 145(1), 1999, pp. 113-122
O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: Effect of metabolic inhibitors and SSRI antidepressants
Authors: Fogelman, SM Schmider, J Venkatakrishnan, K von Moltke, LL Harmatz, JS Shader, RI Greenblatt, DJ
Citation: Sm. Fogelman et al., O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: Effect of metabolic inhibitors and SSRI antidepressants, NEUROPSYCH, 20(5), 1999, pp. 480-490
Risultati: 1-25 | 26-39