XYLITOL PRODUCTION IN REPEATED FED-BATCH CULTIVATION

The ability of Candida parapsilosis to produce xylitol was tested usin g successive substrate supplies, and the importance of the amount of v iable cells in enhancing the conversion rate was demonstrated The suit ability of this yeast for the production of xylitol was investigated i n repeated fed-batch cultivation, using pure xylose or mixtures of xyl ose and glucose. The use of this process increased productivity by abo ut 40% compared with simple batch cultivation without loss of yield of product on substrate. The presence of glucose in the culture medium s eemed to stimulate the specific growth rate, but had no influence over other fermentative parameters.