Bd. Lebowitz et al., DIAGNOSIS AND TREATMENT OF DEPRESSION IN LATE-LIFE - CONSENSUS STATEMENT UPDATE, JAMA, the journal of the American Medical Association, 278(14), 1997, pp. 1186-1190
Objective.-To reexamine the conclusions of the 1991 National Institute
s of Health Consensus Panel on Diagnosis and Treatment of Depression i
n Late Life in light of current scientific evidence, Participants.-Par
ticipants included National institutes of Health staff and experts dra
wn from the Planning Committee and presenters of the 1991 Consensus De
velopment Conference, Evidence.-Participants summarized relevant data
from the world scientific literature on the original questions posed f
or tile conference. Process.-Participants reviewed the original consen
sus statement and identified areas for update, The list of issues was
circulated to all participants and amended to reflect group agreement,
Selected participants prepared first drafts of the consensus update f
or each issue, All drafts were read by all participants and were amend
ed and edited to reflect group consensus, Conclusions.-The review conc
luded that, although the initial consensus statement still holds, ther
e is important new information in a number of areas, These areas inclu
de the onset and course of late-life depression; comorbidity and disab
ility; sex and hormonal issues; newer medications, psychotherapies, an
d approaches to long-term treatment; impact of depression on health se
rvices and health care resource use; late-life depression as a risk fa
ctor for suicide; and the importance of the heterogeneous forms of dep
ression, Depression in older people remains a significant public healt
h problem. The burden of unrecognized or inadequately treated depressi
on is substantial, Efficacious treatments are available. Aggressive ap
proaches to recognition, diagnosis, and treatment are warranted to min
imize suffering, improve overall functioning and quality of life, and
limit inappropriate use of health care resources.