SOL-GEL CARBON COMPOSITE ELECTRODE AS AN AMPEROMETRIC DETECTOR FOR LIQUID-CHROMATOGRAPHY

The performance characteristics of an electrochemical detector for liq uid chromatography based on a sol-gel carbon composite working electro de in a wall-jet configuration are described. The new detector combine s the versatility of sol-gel processes with several favorable characte ristics, including fast electron-transfer kinetics, mechanical rigidit y and renewability. Factors influencing the amperometric response are explored and optimized. Detection limits of 58-170 pg are reported for various neurotransmitters. Repetitive injections yield peak heights w ith relative standard deviations of 2.6-3.7%, The prospects of using s ol-gel derived electrochemical detectors are discussed. (C) 1997 Elsev ier Science B.V.