ASPECTS OF THE ELUTION ORDER INVERSION BY PRESSURE CHANGES IN PROGRAMMED-TEMPERATURE GAS-CHROMATOGRAPHY

Citation
Fr. Gonzalez et Am. Nardillo, ASPECTS OF THE ELUTION ORDER INVERSION BY PRESSURE CHANGES IN PROGRAMMED-TEMPERATURE GAS-CHROMATOGRAPHY, Journal of chromatography, 779(1-2), 1997, pp. 263-274
Citations number
14
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Volume
779
Issue
1-2
Year of publication
1997
Pages
263 - 274
Database
ISI
SICI code
Abstract
The phenomenon of elution order inversion in programmed-temperature ga s chromatography, as a result of only changing the head pressure of th e column while retaining the same temperature program, is known to be experimentally detectable. In this paper we analyze some theoretical a spects of this phenomenon. These aspects concern the dependence of the separation on the pressure program for st couple of analytes presenti ng a retention reversal in isothermal gas chromatography (GC). In the theoretical context, the reason why the pressure program will not have a uniform effect on the separation of all crossing-over couples from a mixture, and why it is not possible to obtain a simple correlation f or the separation of a given couple under different pressure condition s is visualized. A complete simulation of the process is required to e valuate the effect of the chosen head pressure-temperature program on the separation of the solutes. (C) 1997 Elsevier Science B.V.