OBJECTIVE - To determine whether perceived risk and other health belie
fs held by individuals at high risk for developing NIDDM predict weigh
t loss and behavior change during a behavioral weight loss program to
reduce the risk of NIDDM. RESEARCH DESIGN AND METHODS - Health beliefs
and objective risk factors for diabetes were examined in 154 overweig
ht men and women with a family history of NIDDM. The effects of these
factors on adherence, dietary intake, weight. loss, and changes in glu
cose levels were examined in a subset of 79 of these subjects who part
icipated in a 2-year behavioral weight control program. RESULTS - Thos
e subjects who perceived themselves at highest risk of developing diab
etes had a stronger family history of the disease and were more likely
to be women than subjects considering themselves at more moderate ris
k. These participants also rated diabetes as a more serious disease, b
ut were less likely to believe that weight loss would lower their risk
. None of these health beliefs were related to attendance at meetings,
dietary intake, weight loss, or fasting glucose, but higher perceived
seriousness predicted larger reductions in BMI at 1 year. Of the obje
ctive risk factors for NIDDM, higher baseline BMI predicted larger wei
ght losses throughout the program, and a stronger family history of di
abetes was related to greater weight regain after an initial weight lo
ss. CONCLUSIONS - Perceived risk of developing diabetes and other heal
th beliefs did not predict performance in a behavioral weight loss pro
gram. These data suggest that efforts to modify health beliefs by educ
ating high-risk individuals about their risk and benefits of weight lo
ss may not be effective in improving long-term weight loss results.