The prevalence of Chlamydia trachomatis in the lower genital tract and
amniotic fluid of women with preterm prelabour amniorrhexis was asses
sed by DNA amplification for C. trachomatis performed in cervical swab
s and amniotic fluid obtained by amniocentesis. C. trachomatis was pre
sent in the cervix of 20 (23%) of the cases and in six (30%) of those
the organism was also present in the amniotic fluid. There was no asso
ciation with other pathogens in the lower genital tract or amniotic fl
uid. The presence of C. trachomatis was not associated with a signific
ant decrease in the amniorrhexis to delivery interval or with an incre
ase in perinatal mortality or morbidity.