LEWIS-ACID CATALYSIS IN AQUEOUS-MEDIA - COPPER(II)-CATALYZED ALDOL AND ALLYLATION REACTIONS IN A WATER-ETHANOL-TOLUENE SOLUTION

Authors
KOBAYASHI S NAGAYAMA S BUSUJIMA T
Citation
S. Kobayashi et al., LEWIS-ACID CATALYSIS IN AQUEOUS-MEDIA - COPPER(II)-CATALYZED ALDOL AND ALLYLATION REACTIONS IN A WATER-ETHANOL-TOLUENE SOLUTION, Chemistry Letters, (9), 1997, pp. 959-960
Citations number
33
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
9
Year of publication
1997
Pages
959 - 960
Database
ISI
SICI code
0366-7022(1997):9<959:LCIA-C>2.0.ZU;2-M
Abstract
Cu(OTf)(2) was found to be a stable Lewis acid in aqueous media and to activate carbonyl compounds effectively. Aldol reactions of silyl eno l ethers with aldehydes and allylation reactions of tetraallyltin with carbonyl compounds proceeded smoothly in aqueous media, to afford the corresponding adducts in high yields. In addition, the catalyst could be easily recovered quantitatively after the reaction was completed a nd could be reused.