D. Melliere et al., THE TREATMENT OF PATIENTS WITH CAROTID ST ENOSIS IN 1993 - INDICATIONS AND LONG-TERM RESULTS OF SURGERY, Annales de cardiologie et d'angeiologie, 43(5), 1994, pp. 282-285
Cerebrosvascular accidents (CVAs) are the third commonest cause of dea
th in France. Approximately 15 % of them are due to stenosis of the ex
tracranial internal carotid. The fact that a third of CVAs are followe
d by death and another third by major handicaps leads to the need for
careful prevention. This has three aspects: 1) Correction of risk fact
ors: hypertension, smoking hyperglycemia, hyperlipidemia, obesity, alc
ohol abuse, hematological abnormalities and oral contraception; 2) the
prescription of one of two platelet anti-aggregants, the efficacy of
which has been proved: acetylsalicylic acid or ticlopidine; 3) surgica
l elimination of tight carotid stenoses. The following require surgery
: 1) more than 70 % stenosis following cerebral or ocular TIA or minor
CVA; 2) more than 75 % stenosis in asymptomatic patients or with epis
odes of VBI as well as 70 % in case of thrombosis of the contralateral
internal carotid; 3) following a CVA leaving serious sequelae: tight
stenosis when it is reasonable to assume that a further CVA could lead
to clinical worsening or to a loss of independence; 4) symptomatic an
d/or more than 80 % restenosis. The decision should be made only after
confirmation of the diagnosis and of the degree Of stenosis and verif
ication of the absence of any local or systemic contra-indication. The
surgical team must have a low cumulative mortality and perioperative
CVA rate. These patients require ongoing medical monitoring, particula
rly from a cardiological standpoint.