Objective: To compare biopsychologic profiles of women with dyspareuni
a with a matched no-pain control sample, and to determine whether dysp
areunia subtypes based on physical findings have different psychosocia
l profiles from matched controls. Methods: One hundred and five women
with dyspareunia and 105 matched no-pain control women underwent stand
ard gynecologic examination, endovaginal ultrasound, and colposcopy. T
hey also completed a structured interview inquiring about pain other t
han dyspareunia, sexual function, and history of abuse, the Brief Symp
tom Inventory, the Sexual Opinion Survey, and the Locke-Wallace Marita
l Adjustment Scale. Results: In comparison with women who do not exper
ience pain with intercourse, the dyspareunia sample was found to have
more physical pathology on examination, and they reported more psychol
ogic symptomatology, more negative attitudes toward sexuality, higher
levels of impairment in sexual function, and lower levels of marital a
djustment. They did not report more current or past physical or sexual
abuse. However, when the undifferentiated dyspareunia sample was divi
ded into subtypes based on physical findings from the gynecologic exam
inations, the pattern of significant differences from controls varied
according to dyspareunia subtype. Elevated psychologic symptomatology
and relationship maladjustment were confined to the subtype with no di
scernible physical findings who reported levels of sexual function not
significantly different from matched controls. The vulvar vestibuliti
s subtype suffered the highest levels of sexual impairment, although t
his subtype was not characterized by higher levels of psychologic symp
toms than controls. Conclusion: As an undifferentiated group, women wi
th dyspareunia have more physical pathology, psychologic distress, sex
ual dysfunction, and relationship problems. However, this pattern of d
ifferences appears to vary depending on the presence and type of physi
cal findings evident on examination. Dyspareunia is a heterogeneous di
sorder requiring comprehensive gynecologic and psychosocial assessment
to determine differentiated treatment strategies. (C) 1997 by The Ame
rican College of Obstetricians and Gynecologists.