MULTIPLE GRANULAR-CELL TUMOR - A CASE-REPORT AND REVIEW OF THE LITERATURE

Background. Granular cell tumor was first described by Abrikossoff in 1926. It is rare and usually presents as a benign solitary lesion. Mul tifocal and malignant forms are known to occur. Methods. This presenta tion illustrates an additional case of granular cell tumor. Clinical a nd histological features to distinguish malignant and benign forms are presented. Results. Tumor can develop years after therapy for the pri mary lesion. Treatment recommendations are presented. Conclusions. Pat ients diagnosed with granular cell tumor require close follow-up. Radi ographic evaluation for the presence of metastatic disease is necessar y if a malignant Variant is suspected. (C) 1997 John Wiley & Sons, Inc .