In 1990, the Pediatric Hemotherapy Committee of the American Associati
on of Blood Banks developed and distributed a questionnaire addressing
neonatal blood transfusion practices. The same questionnaire was subs
equently sent to Canadian university-affiliated hospitals (n=92). This
report describes the results of the Canadian survey. Seventy-two perc
ent (n=66) of institutions contacted responded. Of these 42% (n=28) ha
d sufficient experience with neonatal transfusions and provided suffic
ient data for analysis. Although the majority of stated practices did
follow published guidelines, several areas of variability and/or subop
timal practices were identified. With respect to component selection a
nd preparation, suboptimal practices included excessive pretransfusion
testing, unnecessary routine washing of RBC concentrates for small-vo
lume transfusions, routine volume reduction of platelet concentrates a
nd the use of suboptimal granulocyte preparations. With respect to tra
nsfusion practices, a disturbingly high percentage of respondents indi
cated that frozen plasma would be given in situations generally consid
ered inappropriate. There was a great deal of variability in the provi
sion of blood components at low risk for CMV, in the use of gamma irra
diation and in the platelet count used for prophylactic platelet trans
fusions. The data collected in this survey provide information concern
ing practices that require improvement, identify areas where further r
esearch is desirable and provide a basis for comparison with current a
nd future neonatal blood transfusion practices. (C) 1997 Elsevier Scie
nce Ltd.